Bo Nix finally has a big play as he sends a ball down the left sideline for Troy Franklin to take in a 35-yard catch - the biggest play of the game so far.

Maybe we'll finally see a touchdown?

Every time the Cardinals seem to be buiding some momentum, something negative happens.

Jacoby Brissett was motoring, with two big completions to Michael Wilson driving his side to the San Fran 27-yard line.

But then he sets off out of the pocket, tries to force the pass and Deommodore Lenoir picks him off.

The 49ers man then produces a sensational weaving return run to take the ball 63 yards and put his side well inside Cardinals territory.

Patrick Mahomes is picked off by the Denver defence after a mad scramble on third down when he tries to float a pass over Ja'Quan McMillian only for the cornerback to leap up and grab the ball, before taking off on a nice return, where he actually fumbles the ball and Mahomes almost dives on it but it bobbles out of bounds.

It's all happening on this play as flags fly in from all angles, one against the Denver sideline as head coach Sean Payton was stood on the white paint and one of the refs ran into him and was sent flying.

That's why some coaches have a guy whose only job is literally to grab the coach to keep him off that sideline paint.

What a crazy few moments. In short - Denver have the ball back!

Field goal - 49erspublished at 23:16 GMT 16 November

23:16 GMT 16 November

San Francisco 49ers 28-10 Arizona Cardinals

A decent enough start to the second half for the 49ers. No touchdown, but a drive that ate up five minutes of clock and resulted in another Eddy Pineiro field goal.

They lead by 18.

ICYMI, here's a reminder of what Shedeur Sanders' famous father Deion Sanders said on the Kelce brothers' New Heights podcast towards the end of September, when asked what advice he'd give the Browns' back-up quarterback after his dramatic draft slide.

"You got to be ready when it's time, but when it's time, you're going to know," said Deion, a two-time Super Bowl winner.

"And it's coming up. I got a prediction. I ain't telling nobody. I got a feeling when it's going to go down. But it's going to go down this year. He's going to get a shot."

He's getting that shot right now, so was he predicting week 11 against Baltimore?

Image source, Reuters

A promising start for Sanders - he completed two passes - but an offensive holding penalty left him chasing yards and the drive ended when he was sacked by Kyle Hamilton.

He also fumbled but it was recovered by a Cleveland player. The Browns punt,

Patrick Mahomes gets Kansas City driving, mainly thanks to pass after pass to Travis Kelce, but when he throws ti Kareem Hunt down at the two-yard line, it's called back for a penalty on lineman Jawaan Taylor.

That offensive line hasn't helped Mahomes.

Sanders' first NFL pass is a five-yard completion to Cedric Tillman.

Dillon Gabriel has not come out after half-time as he is being evaluated for a concussion.

That means Shedeur Sanders will be in at QB for the Browns.

Field goal - Seahawkspublished at 23:02 GMT 16 November

23:02 GMT 16 November

Seattle Seahawks 12-14 Los Angeles Rams

Slowly but surely the Seahawks are creeping back into the game - Jason Myers has to hit his fourth field goal of the game as Sam Darnold can't get them into the end zone, but the Seattle defence is starting to dominate the Rams offence so if this keeps going you'd expect the home defence to tire a bit down the stretch.

P.S - the angle does him no favours but how small does Jason Myers look below? They're big dudes in the NFL so kickers are often the smallest guys on the team, but still....

Image source, Getty Images

The Cardinals have committed so many penalties tonight and another one - offensive holding - nulifies a storming 60-yard touchdown run from Bam Knight.

Image source, Getty Images

The first half ends aptly enough with Patrick Mahomes getting sacked for the second time today - apt as defences have been well on top in their opening 30 minutes, so only right that the final play is a defensive success.

Bo Nix has also been sacked twice and managed just 80 yaards passing to Mahomes' 125, with both quarterbacks being hit four times.

The Chiefs have managed double the first downs Denver have (10-5) but it's all tied up on the scoreboard due to the red zone defence on show, with both sides making two trips each but having to settle for field goals every time.

Work to do for the offensive coordinators at half-time.

Both teams are struggling here, it's a bit of a war of attrition.

Lamar Jackson needs to find a way to get past this super Browns defence.

Dillon Gabriel just needs to get something going to drown out the boos from his own fans.

An instant reply by the Seahawks defence as the Rams, who are already in scoring position, cough up possession thanks to a first fumble of the season by Puka Nacua.

That's a collector's item but shows just how big this game is and how good the Seattle defence can be. Big momentum shift here.

Field goal - Brownspublished at 22:43 GMT 16 November

22:43 GMT 16 November

Baltimore Ravens 10-16 Cleveland Browns

A big mistake from the Ravens extends this Browns drive just before half-time - defensive offside on a punt results in a first down.

The problem is that Dillon Gabriel is really struggling under centre - he's completed just seven passes for 68 yards tonight.

Inevitably, this drive ends in an Andre Szmyt field goal. The Browns are winning but the boos ring out in Cleveland from the home fans.

Shedeur Sanders time?

Patrick Mahomes goes down on a third-and-1 deep in his own territory and the Chiefs are forced to punt it away. Bo Nix has just under two minutes to finish the half with some points.

Right in cue, it's the Rams looking more contender and Seahawks pretender as Sam Darnold throws his second interception of the day right at the start of the second half.

The throw was just behind his receiver as the pass rush got through and into his face, as LA grab a quick turnover in a perfect start to the half.

Eddy Pineiro put those two missed extra points behind him with a 48-yard field goal just before half-time to make it a 12-point lead for the 49ers.

They then picked off Jacoby Brissett with 36 seconds left as the Cardinals looked for a late score.

That gave the 49ers time to get Eddy Pineiro within range of a 62-yard field goal try.

That was blocked by Calais Campbell, but he was called for a personal foul and a 15-yard penalty.

From 47 yards, Pineiro had no issues.

We've seen the Buffalo Bills and Green Bay Packers in action already tonight, now we're watching the Rams, Seahawks, Broncos and Chiefs all playing - but who are Super Bowl contenders and who are just pretenders?

Take a look at who the Whole 10 Yards panel are backing and let us know your picks via the feedback form above.