George Lloyd goes down under Oscar Wallin's challenge and a chance for the visitors to level.

Dilan Markanday gets away the first shot of the game for Leyton Orient after intercepting a loose pass.

He drives towards goal but his effort is deflected behind.

Striker Charlie Kelman almost gets through on goal for Leyton Orient but Lloyd Jones comes in with a strong challenge to thwart his run.

Orient lost two on the bounce for the first time since October coming into this, having previously won 12 of their 15 games before then.

Bottom-side Cambridge, who are looking to record consecutive wins for the first time since October, almost take the lead!

Kell Watts sets himself on the edge of the box and curls in a half-volley but it goes narrowly wide.

The official timing of the John Marquis dismissal for Shrewsbury is 13 seconds.

Shrews boss Gareth Ainsworth said before kick-off his side need seven wins from their final 13 games - if they get one today they'll have pulled it out of the fire.

Charlton's Luke Berry tries to get on the end of a teasing ball into the box but Jayden Sweeney does brilliant in the Orient backline to head it away.

Sixth v seventh in the hunt for a play-off spot at Brisbane Road this afternoon.

Awful start for the visitors.

Inside the first minute the Shrewsbury captain John Marquis has led with his arm in an aerial challenge.

Referee Martin Woods is straight out with the red card.

An early sight of goal within 40 second for Crawley as Kami Doyle drills an effort just wide of the target.

Off we go in 19 games in League One and League Two.

Image source, @Getty Images

Walsall seem to have shaken their turbulent form in recent weeks and are unbeaten in three games.

A dramatic draw with Cheltenham, when the Saddlers conceded twice in added time, will want to be forgotten by boss Mat Sadler.

Despite this they remain top of the league, and with Bradford snatching a last minute winner at Salford they will want to keep their healthy seven-point lead at the top of the division in tact.

Swindon have the slight chance of a late play-off push, and beating the league leaders would give the Robins a glimmer of hope.

Leyton Orient make two changes from their 2-0 defeat at Birmingham on Tuesday night.

Jayden Sweeney and Sonny Perkins come in as Dan Agyei drops to the bench, while Jack Currie is suspended after being sent off in midweek.

Charlton remain unchanged from their 3-0 win over Exeter last time out.

Crawley make three changes from the 3-1 defeat at Blackpool as Armando Quitirna, Rory Feely and Bradley Ibrahim come into the side.

Ben Radcliffe, Max Anderson and Will Swan all drop to the bench.

Neil Harris sticks with the same Cambridge line-up from their 2-0 win over Stockport last weekend.

The Peterborough boss Darren Ferguson has made one change from the league win at Huddersfield last weekend.

Forward Bradley Ihionvien, who started the comeback in the EFL Trophy win at Wrexham in midweek, comes in for just his second league start to replace Ricky Jade-Jones who is on the bench.

Shrewsbury bring in Funso Ojo and Taylor Perry for Alex Gilliead and Vadaine Oliver who are among the substitutes.

Image source, Rex Features

Both Leyton Orient and Charlton Athletic have been on impressive runs to propel themselves into play-off contention, and they go into their clash at Brisbane Road level on 53 points.

The O's had won 12 of 15 before defeats by Bolton and Birmingham halted their progress in the past week.

As for the Addicks, who are seventh and only behind Orient on goal difference, their impressive 3-0 victory over Exeter City last Saturday made it six wins from their past eight games.

Victory for either today will guarantee they end the weekend in one of the play-off spots.

Image source, Rex Features

When is a six-pointer not a six-pointer?

When Shrewsbury Town boss Gareth Ainsworth is managing one of the clubs.

Ainsworth is refusing to see today's match at fellow strugglers Peterborough United as anything other than three points at stake.

But this is a huge fortnight for Shrewsbury with games to come against Bristol Rovers, Exeter City and Burton Albion after the trip to London Road.

There is a seven-point gap to bridge to the safety of 20th place - currently occupied by today's opponents - and when you have lost 20 league games for the fourth successive season there aren't too many pundits giving them a hope of remaining in League One.

As for Peterborough, given their horror of a run which has produced two league wins since 20 December, they've had a good week with a vital victory at Huddersfield Town followed by booking a return to Wembley to defend their EFL Trophy title with a win at Wrexham on Wednesday.

"Wembley is a massive bonus and it's wonderful to be there again," said Posh's goalkeeper Jed Steer after the win at Wrexham.

"But we have to put that to one side and focus on Saturday. It's a big game for both teams. But we simply have to start winning more league matches."

This is big for both teams but remember, it's not a six-pointer...

Image source, Getty Images

Relegation-battling Crawley Town welcome bottom-club Cambridge United to Broadfield Stadium for a vital match between two teams whose hopes of survival will hinge on days like today.

The Red Devils are 22nd and five points adrift of safety following a run of two wins in their past 14 games.

Meanwhile, the U's faint hopes of getting out of danger were boosted with an excellent 2-0 win over promotion-chasing Stockport County last time out in Neil Harris' first game in charge, bringing them within eight points of Peterborough United in 20th.

A repeat of that scoreline today for Cambridge would move them above Crawley and off the foot of the table.

We have plenty more to come from 15:00 (GMT) in League Two, including the leaders Walsall trying to hold the chasing pack at bay.

League Two

• AFC Wimbledon v Bromley
• Cheltenham Town v Grimsby Town
• Chesterfield v Crewe Alexandra
• Doncaster Rovers v Newport County
• Fleetwood Town v Notts County
• Gillingham v Morecambe
• Harrogate Town v Accrington Stanley
• MK Dons v Colchester United
• Walsall v Swindon Town

The top three have finished their work for the day in League One, so now it's over to the rest of the hopefuls and some big games at the bottom from 15:00 (GMT).

League One

• Barnsley v Lincoln City
• Bristol Rovers v Rotherham United
• Burton Albion v Mansfield Town
• Crawley Town v Cambridge United
• Exeter City v Northampton Town
• Leyton Orient v Charlton Athletic
• Peterborough United v Shrewsbury Town
• Stevenage v Huddersfield Town
• Stockport County v Blackpool
• Wigan Athletic v Reading