Sutton's predictions: Leyton Orient v Man Citypublished at 18:32 7 February
Manchester City boss Pep Guardiola will probably make some changes with his side's Champions League tie against Real Madrid coming up on Tuesday, but he won't just field a load of kids.
Instead it will probably be Kevin de Bruyne and Jack Grealish who come into the side, so City are hardly going to be lacking experience.
Leyton Orient have already been one of the stories of this season's FA Cup, thanks to goalkeeper Josh Keeley, who went up for a stoppage-time corner in their second-round win over Oldham and scored a 99th-minute equaliser to force extra time, then Dan Agyei got their winner in the 121st minute.
Orient went on to knock out Championship side Derby County on penalties in round three to earn this tie, but I feel a bit sorry for them because they won't be at full strength here.
They had a good January in terms of making signings but lots of the new players won't be eligible here, and they have some injuries to contend with too.
Saturday's loss at home to Stockport County was their first defeat in 13 games and while they have been in excellent form, they have lost a bit of momentum.
Their manager Richie Wellens is a boyhood Manchester United fan who started his career with the Reds and would love to get one over City, but I don't see it happening for him.
City won't get as many as they did against Salford City in round three, but they are going through. Orient will get a goal, but that's all.
Sutton's prediction: 1-3