Image source, Getty ImagesThis is the 10th time that Tottenham have lost a Premier League game in which they led by 2 or more goals - Spurs are the first club to hit double figures for this and have done so at least three more times than any other side.
Were you at the game or following from elsewhere?
Have your say on Brighton's performance, external
What did you make of Tottenham’s display?, external
Come back to this page on Monday to find a selection of your replies
There are three matches in the Premier League on Sunday and we will bring you every moment.
Aston Villa v Man Utd - 14:00 (listen live on BBC Radio 5 Live)
Chelsea v Nottingham Forest - 14:00
Brighton v Tottenham - 16:30 (listen live on BBC Radio 5 Live)
All kick-off times BST
Chris Sutton is making predictions for all 380 Premier League matches this season, against a variety of guests.
For week seven, he takes on Will Champion and Jonny Buckland from Coldplay, whose latest album, Moon Music, came out on Friday.
Sutton's prediction: 3-3
I love watching Spurs and the same applies to Brighton at the moment.
This should be known as the high-line derby, with the way both teams set up. It will be a great game for the neutral and there should be plenty of chances at both ends.
Brighton lost for the first time under new manager Fabian Hurzeler last week, so this is about how they respond. Can they cause Tottenham problems? Absolutely.
For Tottenham, it is about showing consistency after they put in an outstanding performance to beat Manchester United.
James Maddison was so integral to what they did at Old Trafford, as were the Spurs centre-halves.
As I’ve said many times, Micky van de Ven and Cristian Romero have to be their best players because they get left exposed, but they can handle that.
As I said this on this week's Monday Night Club on Radio 5 Live, while everyone talks about the quality of Arsenal's centre-halves, they always have the full-backs next to them. It is very different for the Spurs duo, because they leave the door open by playing the way they do.
So I am expecting goals, but I actually think Brighton will get something out of the game.
I have always felt that Spurs will soon give someone one hell of a beating sooner or later, but they are going to have to wait until after the international break because it is not happening here.
Will and Jonny's prediction: 2-3
Read the rest of their predictions, and have your own say here
Brighton prepare to host Tottenham on Sunday in a game that could potentially be defined by both teams' tendency to play with a high defensive line.
While Spurs' high line and pressing saw them claim an impressive 3-0 victory at Manchester United last weekend, Albion's came under scrutiny after they conceded four first-half goals at Chelsea.
Discussing the topic on the latest Planet Premier League podcast, former Chelsea and Arsenal midfielder Cesc Fabregas said teams must find the balance of when use a high-line approach.
"Some teams will not have the capacity to understand it, but once they catch you and they understand your game, you will have a lot of problems, especially against the big teams," he added.
"Why do you want a high line if you are not pressuring the ball? If someone is running at you and you are not running back, you only need the good timing of the striker and the good timing of a little pass or chip behind your backline and the guy will be one-on-one against your goalkeeper. Where is the balance?"
Chris Collinson
BBC Sport statistician
It has been a hectic start to the Premier League season with some clubs making a fast start while others are yet to get going.
But whose boots are made for walking the most so far?
Aston Villa's Ezri Konsa has walked the most after six games, just 0.1 km more than Manchester City striker Erling Haaland.
Interestingly, Haaland and Bournemouth striker Antoine Semenyo walk a lot despite being forwards.
Maybe the reason why Haaland has been able to establish himself as one of the fastest players and why Semenyo has made so many sprints is that they conserve their energy for the biggest moments where they can make the most impact.
Meanwhile, it is not just distance walked that we have tracked.
Wolves’ Matheus Cunha has spent more of his time on the pitch walking than any other player in the Premier League so far.
It is also interesting that both of Tottenham’s centre-backs spend so much of their time walking, given Spurs' high possession, high pressing, style of play.
This might mean Cristiano Romero and Micky van de Ven can conserve energy for when things get a bit chaotic (or they fancy a marauding run)?
This could especially be true for van de Ven who has been the fastest player in the competition so far.
Chris Collinson
BBC Sport statistician
There can often be a lot of focus on distances covered and sprints made by teams, but how much of a difference does it really make to their success?
When it comes to distance covered by teams it is the 'battle of the B's' with Bournemouth, Brighton and Brentford having covered the most ground in the Premier League so far this season.
At the other end of the scale, bottom side Wolves have run the least so far - 5km fewer than any other side.
Initially, I thought this could be due to how difficult their start has been (i.e. sitting deep and not rushing out against top opponents), but they actually rank mid-table in pressing stats (with no players missing via red cards either).
But, it is worth noting that running a lot does not necessarily equal success.
Nottingham Forest, Fulham, Chelsea and Aston Villa have also been the 'laziest' teams so far yet have started the season well.
It is a similar story when it comes to sprints too - some good teams sprint a lot, some good teams sprint little.
Tottenham have made the most sprints in the Premier League this campaign, followed by fellow high-pressers Liverpool and Bournemouth.
But defending champions Manchester City have made the least – 60 fewer than any other team – and yet they have been pretty good so far too.
Looking at which teams have made the most sprints – Spurs, Liverpool, Chelsea – and which the fewest – City, Arsenal, Villa – it suggests that playing style plays a part in how much a team sprints as well as just work rate.
Chris Collinson
BBC Sport statistician
Six games down and players are racking up the mileage in the Premier League. But who has been hitting the top marks so far?
Southampton’s Flynn Downes has put in the biggest shift, covering almost five kilometres more distance than any other player in the Premier League so far.
It is also notable too that striker Kai Havertz is working hard for the Arsenal cause as they challenge for the title once again, while Dwight McNeil is backing up his early goalscoring with some serious work rate.
Already the fastest player in Premier League history after clocking 37.8km/h against Brentford last campaign, it is no real surprise to find that Tottenham centre-back Micky van de Ven has been the fastest over the first six games.
However, it is also notable to see Manchester City's ruthless forward Erling Haaland up there too. Speed just one part of the monstrous physicality that gets him so many chances and goals.
Finally, what about the most sprints?
That goes to Newcastle winger Anthony Gordon who has made the most sprints in the Premier League so far this term.
He is 'running' away with it too, having clocked up 13 more than any other player.
Image source, Getty ImagesTottenham manager Ange Postecoglou says Brighton counterpart Fabian Hurzeler "made a real impression on everyone" when he visited the Spurs training ground last year.
"He spent a day with us," Postecoglou explained. "He asked a lot of questions and I gave him too many answers, for sure.
"I actually palmed him off at one stage because he was asking too many. I passed him to the other coaches.
"He was inquisitive about everything. He was already a senior manager, doing a good job, and the fact that he still wanted to ask questions - he made a real impression on everyone."
Spurs visit Brighton on Sunday and Postecoglou was asked whether he would have extended the invitation to Hurzeler had he known that they would be facing each other this season.
"Yes, I would have done," he said. "There's nothing wrong with being a nice person.
"If somebody comes and knocks on your door and wants a cup of tea as a kindred spirit, you let him in your house. He's not going to take the furniture or steal the cutlery. You kind of trust that."
Image source, Getty ImagesJust one of the 14 Premier League meetings between Brighton and Tottenham has finished as a draw (1-1 in April 2018), with Spurs winning nine to the Seagulls' four.
Katie Stafford
BBC Sport journalist
Tottenham boss Ange Postecoglou has been speaking to the media before Sunday's Premier League game against Brighton (kick-off 16:30 BST).
Here are the key lines from his news conference:
Captain Son Heung-min is "pushing hard" for a return to the matchday squad but is not available for Sunday's game.
He says his side "are tired" from Thursday's Europa League game at Ferencvaros but there are no new injury concerns. Destiny Udogie, who missed that game, is expected to be available.
On James Maddison not being included in Lee Carsley's England squad for the Nations League: "I'm sure he is disappointed. He's playing well, but sometimes that is all you can do."
However, he is not surprised by Dominic Solanke's England call-up and added it "is all down to him as I've only had him for a month".
He says his time at Spurs "has flown by" with the victory at Ferencvaros marking his 50th game in charge of the club: "Hopefully, the next 50 [games] is going to be where there will be a real impact."
On last season's defeat to Albion: "It was a curious one. We started the game really poorly but it could have ended up 4-4. It was kind of indicative of our season but was overshadowed with things we struggled with last season, the consistency of our performances."
On a shift in mood following positive results: "Fourteen days ago, it felt like there was a lot of suffering. There is such a fine line."
Follow all of Friday's Premier League news conferences and the rest of the day's football news
Listen to full commentary of Brighton v Tottenham from 16:30 BST on Sunday on BBC Radio 5 Live
Image source, Getty ImagesBournemouth manager Andoni Iraola says he is not "surprised" Dominic Solanke had been named in his first England squad for seven years, but added the former Cherries striker also "deserved" to be called up last season.
The Cherries boss was asked about the now-Tottenham striker's achievements and said he was delighted for the 27-year-old.
"I'm very happy and pleased," Iraola said. It is not a surprise. I think he was deserving of the call-up even last season. I'm happy that he now has the chance and I'm sure he is going to play well."
Iraola also outlined his belief that national team managers tend to "pay more attention" to players who are playing in European competitions with their clubs.
"I think it happens in every country," the Spanish manager said. "When they see you playing for teams that play in Europe, they pay more attention. It is the same everywhere.
"Last season, I think Dom was incredible for us - not only for the goals he scored but his performances overall were amazing. He probably deserved the call-up before now.
"But I'm very happy for him, even if he isn't our player anymore. We wish him all the best and I was very pleased that he was called up."
Image source, Getty ImagesAfter scoring Brennan Johnson made it five goals in each of his past five appearances for Tottenham, the club has posted a picture, external likening him to Ronaldo.
The post follows team-mate James Maddison sharing the same image on Instagram last Monday after Johnson put Spurs in front for their 3-0 win at Manchester United last weekend.
The Wales international is in great form for the north London side. His five goals already matches his entire goal tally of last season.
Johnson will hope to continue his goalscoring form when Spurs travel to Brighton at the weekend.
Image source, Getty ImagesWe asked for your views after Tottenham continued their winning start to the Europa League with victory over Ferencvaros in Hungary.
Here are some of your comments:
Paul: A good win and performance from a very young and inexperienced team. All of the youngsters were heavily involved throughout and they can all be happy with their contributions. It gave Ange Postecoglou an opportunity to rest some of the squad prior to Brighton. It was good for him to get a good look at Mikey Moore and Will Lankshear, as both will be challenging for more game time.
Len: It was solid enough. Most of the first team were left out or left on the bench, but we always had something in hand. Brennan Johnson scored again - for the fifth consecutive time. It was a good display. Spurs are on the rise.
Joe: Yes it was a win, which is great, but defensively we were an unmitigated disaster. We seemed intent on giving away goals. We gave the ball away so cheaply and so frequently through downright sloppy passing. Also, how often did we look like scoring?
Julian: It was good to see our young players being given a chance. Moore was excellent. Lankshear came close to scoring. Archie Gray had an excellent 60 minutes but then came out of position too often. Lucas Bergvall needs to work on his speed and fitness although he is technically good. I hope they all get more opportunities, especially as Timo Werner seems incapable of scoring.
Paul: Even against lower quality opposition, Werner is having no impact on the game. How much longer is the manager going to persevere with him?
Image source, Getty ImagesTottenham boss Ange Postecoglou speaking about his four teenage starters after Europa League win over Ferencvaros: "The first thing is that they're part of our first team squad, not because I want some young players, it's because they've earned that spot.
"Then it's about how to help them develop and the moments we need to put them in there, the moments we need to hold off. And we can't discount the fact that Archie [Gray] is 18, Lucas [Bergvall] is 18.
"I thought Archie was brilliant. We asked him to play in two different positions and it's incredible how he just adjusts and he's able to bring his game to wherever he put him.
"Lucas worked hard and Will [Lankshear] was unlucky with a couple of moments when we could have got a goal.
"These guys are there because they've earned their spot but they're an important part of our development.
"Whilst we want to be a team that has an impact this year, it's like I said before, it's important we're developing players along the way so that whatever sort of period of potential for success or opportunity for success exists, it's elongated because of the young players you got through."
On Mikey Moore: "I thought Mikey was outstanding. It's brilliant for a 17-year-old to play 90 plus minutes in a European away tie.
"He just handled it superbly, I kind of knew he would and I think it'll help his growth as a footballer once you get through an experience like that.
"I think he'll grow and evolve and I didn't feel like I needed to take him off. He still looked strong at the end and was still contributing.
"If you look at the Premier League, how many 17-year-olds are actually contributing and Mikey is already, which shows that he's got something special but we've just got to be really careful about how we develop that."
Michael Emons
BBC Sport journalist
Image source, Getty ImagesMikey Moore was making his first start after five substitute appearances for the club
It looked risky for Ange Postecoglou to name four teenagers in his starting line-up, but his faith in his young players paid off as Tottenham beat Ferencvaros to record their second win in two Europa League matches.
Postecoglou included winger Mikey Moore, 17, for his first start, midfielder Lucas Bergvall, 18, defender Archie Gray, 18, and 19-year-old striker Will Lankshear, who was making his senior debut.
Moore was heavily involved in Tottenham’s first goal, scored by Pape Sarr, with Moore and Gray also involved in the build-up to what proved the decisive goal from substitute Brennan Johnson as Spurs fought hard to win in the Budapest rain.
"They’re part of our first-team squad, not because I want some young players, it’s because they’ve earned that spot," said Postecoglou. "They’re an important part of our development. While we want to be a team that has an impact this year, it’s important we’re developing players along the way."
But the strongest praise was reserved for Moore, with Postecoglou saying: “I thought Mikey was outstanding. It’s brilliant for a 17-year-old to play 90-plus minutes in a European away tie. He just handled it superbly, I kind of knew he would and I think it’ll help his growth as a footballer."
Spurs fans can expect to see a lot more of the teenage quartet throughout the rest of the season.
Image source, Getty ImagesTottenham midfielder Pape Matar Sarr has registered a goal involvement in each of his past three games in all competitions for the north Londoners (two goals, one assist), after a run of 17 with none.
Meanwhile, forward Brennan Johnson has scored in each of his past five appearances for Spurs in all competitions, with his five goals in that time as many as he managed in his previous 38 games for the club.
Image source, Getty ImagesTottenham made it two victories from their two Europa League games as a youthful side won in Hungary against Ferencvaros thanks to goals from Pape Matar Sarr and Brennan Johnson.
There are three European fixtures on Thursday involving Premier League clubs:
Ferencvaros v Tottenham (17:45) - Europa League
Porto v Man Utd (20:00) - Europa League (listen on BBC Radio 5 Live)
Chelsea v Gent (20:00) - Conference League
All kick-off times BST
Interim England boss Lee Carsley has announced his squad for this month's Nations League games with Greece and Finland.
Tottenham striker Dominic Solanke is the headline inclusion, returning to international contention for the first time in seven years.
The 27-year-old has three goals in six appearances for Spurs since moving from Bournemouth in the summer.
