Postpublished at 20:07 Greenwich Mean Time 26 February 2015
Two goals from midfielder Vitolo helped defending champions Sevilla secure a 3-2 away win at Borussia Monchengladbach and book a place in the last 16 with a 4-2 aggregate victory.
Dutch champions Ajax cruised into the next round as Arkadiusz Milik, who also scored in the first leg at the Amsterdam ArenA, bagged a brace in a 3-0 win at Legia Warsaw to secure a 4-0 aggregate win.
Spanish side Villarreal - semi-finalists in 2011 - were made to work by FC Red Bull in Salzburg but two goals for Luciano Vietto and a late strike from Giovani Dos Santos eventually secured a 3-1 away win - 4-2 on aggregate.