Watford XI: Gomes, Nyom, Prodl, Cathcart, Holebas, Capoue, Behrami, Anya, Ighalo, Jurado, Deeney.
Southampton XI: Stekelenburg, Yoshida, Fonte, Caulker, Targett, Wanyama, Romeu, Soares, Mane, S Davis, Pelle.
Watford v Southampton (16:00 BST)
In the last season that these two sides met (2011-12), Southampton won both home and away without conceding a goal in either match.
The next goal scored at Vicarage Road will be the 100th Premier League goal scored at the home of Watford.
Watford tally of 58 interceptions after the first two matches of the Premier League was more than any other side.
Watford v Southampton (16:00 BST)
Quote MessageSouthampton cannot afford to let any players go. Once you have got your squad together you should close the transfer window. It does distract players, whatever people say.
Former Southampton manager Dave Merrington
Watford v Southampton (16:00 BST)
Southampton have had clubs beating down their door and trying to sign the club's players so often it appears manager Ronald Koeman has had enough.
Sadio Mane is the latest of the south coast side's players to be courting admiring glances, with Manchester United rumoured to be targeting the attacking midfielder.
"We know we still have the transfer deadline on 1 September that we have to deal with," Koeman told BBC Radio Solent. "It’s not nice, it’s sometimes difficult, but everybody knows that we don’t sell any more players.
"If they are interested, then maybe they come back next year."
Image source, Getty ImagesWatford v Southampton (16:00 BST)
Image source, Getty ImagesWatford boss Quique Sanchez Flores: "We want to get our first win. We are ready to get off the mark.
"Southampton play with the ball, they try to play well with quick, fast players on the counter-attack. They sometimes mix their play, so we will need to think about these things."
Watford v Southampton (16:00 BST)
One of the eagle-eyed officials at Vicarage Road noticed a crossbar wasn't straight. It had to be sorted before referee Andre Marriner then made sure Hawk-eye was working properly in some early action before the game.
Image source, Getty ImagesWatford v Southampton (16:00 BST)
Image source, .Watford v Southampton (16:00 BST)
Image source, .Watford v Southampton (16:00 BST)
Watford v Southampton (16:00 BST)
Let's get straight into the team news. Watford make one change from their draw with West Brom last time out as defender Jose Holebas comes in for Miguel Layun.
Watford XI: Gomes, Nyom, Prodl, Cathcart, Holebas, Capoue, Behrami, Anya, Ighalo, Jurado, Deeney.
Southampton make two changes from their midweek Europa League outing as defender Cedric Soares and midfielder Steven Davis replace James Ward-Prowse and Jay Rodriguez.
Southampton XI: Stekelenburg, Yoshida, Fonte, Caulker, Targett, Wanyama, Romeu, Cedric Soares, Mane, Steven Davis, Pelle.
Watford v Southampton (16:00 BST)
Image source, .How do you think this game will go? Whatever you think the score will be why don't you check out our Premier League predictor? You can guess the score between Watford and Southampton as well as every single Premier League result this season.
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Watford v Southampton (16:00 BST)
Watford and Southampton - based on the expectation on them - have both had differing starts to the season as they go into this game searching for their first league win of the season.
The Hornets have looked good in their opening two top flight outings as they have drawn with Everton and West Brom.
Southampton were last season's surprise package but followed up a draw at Newcastle with defeat by Everton. They have also played three Europa League qualifiers - the latest seeing them held 1-1 by FC Midtjylland at home.
Game on at Vicarage Road then.
Image source, Getty Images