Vitolo tries to dribble into the Barcelona box but he's surrounded by about four defenders, who combine to get the ball off him.

Ten-man Barca, who have lost a 59-goal striker, are on the ropes here.

Sevilla have midfielder Sebastian Cristoforo, winger Yevhen Konoplyanka and striker Fernando Llorente warming up on the touchline. Is boss Unai Emery going to go for the kill?

It is less than two weeks before the Copa America starts. Luis Suarez is Uruguay's star man.

Better news for Barcelona is that Lionel Messi is able to continue after getting a whack to the head a few minutes ago.

It looks like Luis Suarez hurt himself while stretching for the ball. He is limping really badly and is replaced by attacking midfielder Rafinha. You get the impression a striker would have replaced him if they had 11 men.

Image source, Reuters

A stretcher comes on for Luis Suarez, who is the in-form player on the planet. The Uruguayan star had scored 14 goals in his last five games. And he's coming off.

Image source, AP

And now Luis Suarez goes down to the ground. What's happening to Barcelona's front line?

Barcelona star Lionel Messi, who has been quiet today, is down on the ground in pain after getting a clattering from Daniel Carrico, who headed clear a cross into the box.

He's getting treatment...

Image source, AP

Laurent Nkunda: Even if they lose this game Sevilla had more successful season than Barcelona. 

Sam Gachohi: Vicente Calderon must be the venue of nightmares for Barca..isn't this where their European dreams went up in smoke?

Gerard Pique, whose intervention there probably denied Sevilla the opener, then slides Kevin Gameiro to get the ball out for a corner.

Is he going to be crucial to Barcelona's hopes here?

Sevilla are desperately unlucky not to be ahead in the 2016 Copa del Rey final. 

Ever Banega fires in a shot from 20 yards, Gerard Pique gets a leg onto it and it hits the post, then rolls across the line behind Barca keeper Marc-Andre ter Stegen, who was beaten.

Sevilla make nothing of the corner. And a minute later Neymar is behind their defence but he's flagged offside. But he was onside...

A let-off there for the 11 men of Sevilla.

The second half is under way and Sevilla already have a corner. Ever Banega's shot from outside the box is deflected wide by Gerard Pique.

Barcelona boss Luis Enrique makes a change, with Jeremy Mathieu coming on at centre-back. Ivan Rakitic, the former Sevilla midfielder, is the man to come off.

Remember they had defender Javier Mascherano sent off in the first half.

Javier Mascherano's red card is the first time a Barcelona player has been sent off in the first half since August 2014, when he saw red against Elche.

Javier Mascherano is the only Barcelona player to have been sent off twice this season.

Image source, Getty Images

Bazainez: Quarter-final of Champions League: not successful lost in league vs Valencia and Real Sociedad. No, it has been an awful season 

Cyrus Katabula: That's how high Barca has set the bar. You win it all again, but if you miss out on the Champions League trophy, you are considered a failure.  

Seth Gogo Egoeh: Sevilla seems more fresher than Barcelona and that's incredible considering they had few days to recuperate. 

The half-time whistle goes. A lot of whistles from Barcelona fans, presumably at Javier Mascherano being sent off. But it was the right decision.