Alan: Looking at the Man Utd team, Mourinho clearly wants the sack before Xmas to spend some quality time with his family. Dear oh dear. We will lose tonight and quite badly. Please grant him his wish. These are sad times.

Guy Mowbray
Match of the Day commentator

On 7 November, Manchester United won at Juventus. It was yet another win from behind that poured water on the fire of speculation about Jose Mourinho's future.

Four Wednesdays - and three Premier League games without a win - later, that fire is raging once more, amid stories of Mourinho's own rage after another comeback from defeat at Southampton.

Now, in a game that used to mean so much to both sides, United must start well for a change against a team for whom change looks to have been a good thing.

There's something more, well, 'Arsenal' about Arsenal again, and they'll fancy their chances of a first league win at Old Trafford for over 12 years.

Simon Stone
BBC Sport

In his programme notes tonight, Jose Mourinho says his players 'have to remember the saying simplicity is genius'.

Yesterday Mourinho refused to say whether he had called Paul Pogba 'a virus' after Saturday's draw at Southampton.

He did say after the match that his midfield was poor though - and with Pogba dropped to the bench tonight, it is not hard to identify who Mourinho views as being the main culprit.

Image source, .

Yes, Manchester United are dealing with a few injuries, but it just seems like chaos, doesn't it?

Does anyone know what their best XI is? Jose could pick his team out of a hat at the moment.

Big changes for Manchester United. Paul Pogba drops to the bench along with striker Romelu Lukaku. Jesse Lingard and Anthony Martial start in their places.

Elsewhere manager Jose Mourinho has rejigged the defence in the wake of the 2-2 draw with Southampton. Eric Bailly and Chris Smalling have recovered from injuries to make the starting XI alongside Marcos Rojo, who is promoted from the bench. Matteo Darmian comes in for Luke Shaw at left-back with Diogo Dalot making his first Premier League start in place of the suspended Ashley Young on the other flank.

Summer signing Fred is not in the matchday squad. Marouane Fellaini is on the bench with Nemanja Matic moving up into midfield after being deployed as a makeshift centre-back at St Marys.

Arsenal make two changes from the derby win over Tottenhan with Aaron Ramsey coming in for Henrikh Mkhitaryan and Matteo Guendouzi replacing the suspended Granit Xhaka in midfield.

Striker Alexandre Lacazette, who came off the bench to score against Spurs at the weekend, is among the substitutes once more.

Adam: Despite our league position Liverpool have hardly been setting the world alight of late. Few lads will be fresh, full of running and glad of the minutes. Given the fixture congestion I think it makes sense!

Tottenham defenders Kieran Trippier and Toby Alderweireld return to the starting XI, as manager Mauricio Pochettino makes five changes to the side that lost 4-2 to Arsenal last weekend.

Trippier has been missing since early November with a groin injury, and replaces Serge Aurier. Alderweireld comes in for suspended centre-back Jan Vertonghen, and Danny Rose is in for Ben Davies.

Midfielders Harry Winks and Lucas Moura come in for Moussa Sissoko and Dele Alli, who starts from the bench.

Tottenham XI: Lloris, Trippier, Foyth, Alderweireld, Rose, Dier, Winks, Lucas Moura, Eriksen, Son, Kane.

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Southampton interim boss Kelvin Davis makes four changes to the XI that started in the 2-2 draw against Manchester United.

Steven Davis, James Ward-Prowse, Manolo Gabbiadini and Matt Targett replace Jannik Vestergaard, Yan Valery, Mario Lemina (suspended) and Michael Obafemi (injury).

Southampton XI: McCarthy, Cedric, Yoshida, Stephens, Targett, Hojbjerg, Davis, Redmond, Ward-Prowse, Armstrong, Gabbiadini.

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A quick internet check confirms that this actually happened...

Kyle: When the head of the Kuwait FA came onto the pitch and demanded that a France goal was disallowed due to a whistle in the crowd and after a while the referee agreed. That's absolutely bonkers.

Phil McNulty
BBC Sport chief football writer at Old Trafford

No Paul Pogba or Romelu Lukaku in the Manchester United team. A big story even before kick-off and a high-risk selection from Jose Mourinho.

John: Why do I get the feeling this is going to backfire? When you’re up against a team battling for survival, you need to be as ruthless as possible because the opposition have nothing to lose

Plenty of changes. Paul Pogba and Romelu Lukaku dropped. Manchester United full-back Diogo Dalot makes his first Premier League start, with Eric Bailly playing for the first time in two months.

Aaron Ramsey captains Arsenal with Matteo Guendouzi replacing Granit Xhaka.

Kieran Tripper returns for Spurs, with Southampton's caretaker boss making four changes.

Chelsea boss Maurizio Sarri is asked by BBC Sport's Jonathan Pearce if he made changes with Saturday's game against Manchester City in mind.

"No. I think we need to think only of this match. I changed it only because we have to play 11 matches in 35 days so somebody has to rest. It will be very difficult.

"Ruben Loftus-Cheek has a very great physical impact. He's improving from the tactical point of view. He can do everything on the pitch and give us a lot.

"Manchester City are in another category. We just have to think about the top four. At the moment we are not able to fight with Manchester City."

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Eighteen-year-old midfielder Morgan Gibbs-White starts a Premier League match for the first time as he is one of three Wolves changes from the side that began the 2-1 loss to Cardiff City on Friday.

There are also recalls for Ryan Bennett and Diogo Jota; Helder Costa and Adama Traore drop to the bench, while Ruben Neves is suspended.

Wolves: Rui Patricio, Bennett, Coady, Boly, Doherty, Joao Moutinho, Saiss, Ruben Vinagre, Gibbs-White, Jota, Jimenez.

Substitutes: Ivan Cavaleiro, Helder Costa, John Ruddy, Hause, Dendoncker, Leo Bonatini, Traore.

Image source, .

Maurizio Sarri makes five changes to the Chelsea side that started the 2-0 win over Fulham on Sunday, with Cesc Fabregas, Ruben Loftus-Cheek and Andreas Christensen all starting in the Premier League for the first time this season.

Elsewhere, Alvaro Morata starts in place of Olivier Giroud up front, while Pedro, who scored in that win at the weekend, drops to the bench with Willian starting.

Chelsea: Arrizabalaga, Azpilicueta, Rudiger, Christensen, Alonso, Kante, Fabregas, Loftus-Cheek, Willian, Morata, Hazard.

Substitutes: Jorginho, Pedro, Caballero, Kovacic, Giroud, Zappacosta, Luiz.

Image source, .

Just the 12 changes between the two teams...

Burnley make five from the side that started the 2-0 defeat at Crystal Palace on Saturday.

Defenders James Tarkowski and Phil Bardley, forward Ashley Barnes and midfielders Robbie Brady and Ashley Westwood all start. Matthew Lowton, Kevin Long, Jeff Hendrick, Steven Defour and Aaron Lennon drop out.

Burnley XI: Hart, Bardsley, Tarkowski, Mee, Taylor, Gudmundsson, Westwood, Cork, Brady, Barnes, Wood.

Substitutes: Heaton, Lowton, Vokes, Hendrick, Lennon, Vydra, Long

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SEVEN changes for Liverpool from the side that started the 1-0 win over Everton on Sunday.

The only survivors are keeper Alisson, defenders Joe Gomez and Virgil van Dijk, and Xherdan Shaqiri.

Sadio Mane, who suffered a foot injury on Sunday, is not in the 18, while Mohamed Salah and Roberto Firmino are among those on the bench.

Liverpool XI: Alisson, Gomez, Matip, van Dijk, Moreno, Milner, Henderson, Keita, Shaqiri, Sturridge, Origi.

Substitutes: Fabinho, Firmino, Salah, Lallana, Mignolet, Alexander-Arnold, Camacho.

Everton make three changes to the side that was beaten 1-0 in the Merseyside derby at Anfield on Sunday.

Kurt Zouma replaces Michael Keane, while Cenk Tosun and Ademola Lookman are in for Bernard and Theo Walcott.

Everton: Pickford, Zouma, André Gomes, Sigurdsson, Digne, Mina, Tosun, Gueye, Coleman, Richarlison, Lookman

Replacements: Stekelenburg, Baines, Keane, Walcott, Bernard, Davies, Calvert-Lewin

Image source, BBC Sport

Rafael Benitez has also made three changes to his Newcastle side that were comfortably beaten 3-0 at home to West Ham at the weekend.

There is no room for Kenedy or Matt Ritchie in the squad, while Ayoze Perez drops to the bench.

Jamaal Lascelles returns to skipper the side as Christian Atsu and Jacob Murphy start.

Newcastle: Dubravka, Sung-yueng, Schar, Lascelles, Murphy, Rondon, Diame, Fernandez, Manquillo, Yedlin, Atsu

Replacements: Woodman, Clark, Shelvey, Muto, Perez, Joselu, Longstaff

Image source, BBC Sport

Image source, BBC Sport

Fulham manager Claudio Ranieri makes two changes to the team that lost at Chelsea on Sunday. Argentine midfielder Luciano Vietto and forward Aboubakar Kamara start with Tom Cairney and Stefan Johansen dropping out.

Fulham XI: Rico, Christie, Mawson, Chambers, Odoi, Le Marchand, Seri, Vietto, Sessegnon, Mitrovic, Kamara

Subs: Bettinelli, Kebano, Cairney, Ream, Schurrle, Bryan, Zambo

Image source, BBC Sport

Leicester City manager Claude Puel makes four changes to the side that defeated Watford on Saturday.

The most noticeable omission is Jamie Vardy, who has suffered a recurrence of a groin injury in training. Jonny Evans, Ricardo Pereira and Demarai Gray also drop out with Caglar Soyuncu, Kelechi Iheanacho and Fousseni Diabate coming in.

Leicester City XI: Schmeichel, Simpson,, Morgan, Soyuncu, Chilwell, Albrighton, Mendy, Ndidi, Diabate, Maddison, Iheanacho

Subs: Ward, Gray, Pereira, Okazaki, Iborra, Fuchs, Knight

Matt Wilkinson: Do not like the Liverpool team that’s selected tonight. Moreno is a liability and just think Sturridge is not mobile enough. Can see Burnley causing problems here!

RegularJon: What are these managers playing at? Really have it in for my fantasy team don’t they?! Have some consideration men!

Image source, Reuters

Not long ago, Charlton Athletic fans threw packets of crisps on to the pitch and Luis Figo was once infamously the subject of a pig's head.

There must be loads of strange disruptions in the amateur game.

This one will take some beating, though. Yakubu tries to remove a chicken from Ewood Park during the height of the protests against Venky's.

You don't hear much about Venky's these days, do you?

Image source, Getty Images