Postpublished at 19:53 British Summer Time 11 October 2018
Wales 0-0 Spain
Danny Gabbidon
Former Wales defender on BBC Radio 5 Live
The fans will be looking for Wales to come out of the blocks fast and let Spain know they are in a game.
Alcacer scores twice and Ramos - booed by home crowd - heads in
Sub Bartra adds fourth in second half
Vokes heads in late consolation for Wales
First Wales game at Principality Stadium since 2011
Bale misses match with groin injury
Wolves' Jonny comes on for Spain debut
Live commentary on BBC Radio 5 live
Emma Sanders
Wales 0-0 Spain
Danny Gabbidon
Former Wales defender on BBC Radio 5 Live
The fans will be looking for Wales to come out of the blocks fast and let Spain know they are in a game.
Wales 0-0 Spain
Spain try to feed it through for Suso down the right-hand side but it's cut-out by Ben Davies.
The visitors keep the ball though, but have to send it all the way back to David de Gea and go again.
Wales 0-0 Spain
Dafydd Pritchard
BBC Sport Wales at the Principality Stadium
Boos for Sergio Ramos as soon as he touches the ball just a few seconds after kick-off.
Spain's captain is known as a pantomime villain for his aggressive - and occasionally theatrical - approach, and he also happens to be one of the world's best centre-backs.
It will be a different challenge for the serial Champions League winner tonight, though, with burly Burnley striker Sam Vokes leading the Welsh attack.
Wales 0-0 Spain
Aaron Ramsey puts pressure on the Spanish defence before Ethan Ampadu wins a free-kick in the middle of the park.
Wales with the possession now.
Wales 0-0 Spain
And we're off.
Wales v Spain (19:45 BST)
A minute's silence is being held before kick-off as victims of the Majorca floods are remembered.
The flash flood on the Spanish island killed at least 10 people this week. Tennis legend Rafael Nadal is among those from the sporting world to show his support.
Wales v Spain (19:45 BST)
The Welsh national anthem is roared around the stadium. The players look pumped.
Goosebumps!
Wales v Spain (19:45 BST)
Ryan Giggs speaking to Sky Sports: "I think we have real strength in depth at the moment. A few players are missing - Gareth Bale is obviously a special player and any team would miss him - but it gives others a chance to step up.
"Just driving in here brings back fond memories. Some players have never been here before. I told them to embrace it and enjoy it.
"We will have to play well. Individually, [the Spanish players] are all at big clubs and have played at the highest level but we are looking forward to the challenge.
Wales v Spain (19:45 BST)
The players are coming out of the tunnel and we're now just minutes away from kick-off.
Score predictions? I'm going for goals in each half.
#bbcfootball
Dave: All of them on the international stage, a great group of youngsters.
Wales v Spain (19:45 BST)
Wales have won one, drawn two and lost two of their five matches against Spain.
Ryan Giggs has lost two of his first five matches in charge - as many defeats as Wales suffered in 12 games prior to his appointment.
Wales have failed to score in three of their past four games in all competitions, as many instances as in their previous 13 matches.
Spain have not lost inside 90 minutes since they were beaten by Italy at Euro 2016 - 26 matches ago.
Their only defeat of any sort since then was a penalty shootout loss to Russia in the second round of the 2018 World Cup.
Wales v Spain (19:45 BST)
Wales captain Ashley Williams: "This is the strongest squad that I've seen since I've been playing for Wales.
"It does give us, the older ones, a bit of a push and you know you have to be playing well for your club team, playing every game.
"And when you come here you have to do well, which is what it should be like.
"In every position, we've got at least one or two players who are ready to go straight into the starting XI."
#bbcfootball
Mr Lobby: Wilson. Woodburn should have stayed at Liverpool - he needs to be playing.
Pete Crowther: Ampadu without doubt.
Wales v Spain (19:45 BST)
Spain have looked good since their shock exit from the World Cup following defeat by hosts Russia in the last 16.
They travelled to Wembley to take on an England side who had surpassed expectations by reaching the World Cup semi-final, and won 2-1.
In their last game, they thrashed World Cup finalists Croatia 6-0 thanks to five different goalscorers and an own goal.
Spain's two wins out of two in the Nations League see them top Group 4A with six points and they will be hoping to carry that momentum into tonight's friendly.
Wales v Spain (19:45 BST)
Here's at bit of nostalgia...
Wales claimed a historic 3-0 victory over Euro 1984 runners-up Spain in Wrexham in 1985.
Ian Rush opened the scoring at the Racecourse with a first-half tap-in before Mark Hughes produced this memorable scissor-kick goal which sent the fans into raptures.
Wales won that match comfortably but failed to qualify for the 1986 World Cup just a year later.
#bbcfootball
Liam Griffin: Never mind Connor Roberts, Tyler Roberts is the future. Guna be some player that kid.
Tommy G: Amps...classy.
Wales v Spain (19:45 BST)
John Southall
BBC Radio 5 live football reporter
It’s a pleasure to be back at the Principality Stadium. I know some fans don’t like Wales playing football here but on a night like tonight against Spain it looks a good decision.
We should have a crowd of 50,000+ and with the roof shut it should be lively. Wales haven’t played here since 2011 and they haven’t played Spain since 1985 when Mark Hughes scored a Mark Hughes goal (scissor kick!).
Wales are playing three at the back and it’s not the familiar Spain side but there’s still the likes of de Gea, Azpilicueta, Ramos, Saul, Suso, Morata and a very strong bench, so an interesting test for Wales.
Wales v Spain (19:45 BST)
Brentford and Wales defender Chris Mepham reflects on his rise from North Greenford reserves to the international stage.
The 20-year-old has now won four caps for Wales since making his debut against China in March 2018.
Wales v Spain (19:45 BST)
The decision to switch venues has been supported manager Ryan Giggs, who is looking forward to returning to where he played for Wales on several occasions.
"It's exciting. It's a new stage, a new venue and, like always, I want them to express themselves," said Giggs.
"We're up against quality opposition so they'll have to be on top of their game.
"All the young players and the older players are excited as well - a lot of them have played there before."
Wales v Spain
Dafydd Pritchard
BBC Sport Wales at the Principality Stadium
This is the first time Wales have played at the Principality Stadium since they lost 2-0 to England here in 2011, and their return to the 74,500-capacity home of Welsh rugby has split opinion among followers of the national football team.
In the intervening seven years, fans have packed the smaller Cardiff City Stadium to create a fervent atmosphere - in stark contrast to the dwindling crowds of Wales' latter years at the Principality Stadium, then known as the Millennium Stadium.
The huge arena was full when it first hosted Wales matches, with capacity crowds watching Mark Hughes' side beat Germany and Italy among others in the early noughties.
And it is another glamour tie, tonight's friendly against Spain, which has convinced the Football Association of Wales to move the team back here, albeit just for tonight.
Almost 50,000 tickets have been sold already, so the FAW is hoping a sizeable crowd and a lively atmosphere will justify the switch.