Arsenal make two changes to the XI that started in the 2-0 loss against Leicester.

Left-back Kieran Tierney and central defender Sokratis replace Rob Holding and Sead Kolasinac.

There were reports Granit Xhaka might return to the matchday squad, but he is absent for the fifth game.

Arsenal XI: Leno, Chambers, Papastathopoulos, Luiz, Bellerin, Torreira, Guendouzi, Tierney, Ozil, Lacazette, Aubameyang

Subs: Maitland-Niles, Pepe, Mustafi, Nelson, Martinez, Willock, Martinelli.

Image source, BBC Sport

Southampton make three changes to the line-up that started in the 2-1 defeat against Everton.

Michael Obafemi, Ryan Bertrand and Pierre-Emile Hojbjerg come into the XI - Jannik Vestergaard, Oriol Romeu and Moussa Djenepo are out.

Southampton XI: McCarthy, Cedric, Bednarek, Stephens, Bertrand, Ward-Prowse, Hojbjerg, Armstrong, Obafemi, Ings, Redmond.

Subs: Yoshida, Long, Djenepo, Romeu, Boufal, Gunn, Valery.

Image source, BBC Sport