Good, strong effort by Marco Asensio but Antaolii Trubin pushes away the danger.

The 19-year-old goalkeeper has done well on his Champions League bow, although he hasn't been massively troubled. I doubt he was expecting that when he was told he would be playing against the Spanish giants.

Image source, BBC Sport

Nice and simple from the champions as they make just one change from the team who won 4-1 on league duty at the weekend. Joshua Kimmich comes in for Serge Gnabry.

Atleti make six changes as we are deprived of the feisty duo of Luis Suarez and Diego Costa up front. Suarez starts but is partnered by Joao Felix.

Chris Bevan
BBC Sport at Etihad Stadium

Manchester City make two changes from the side that beat Arsenal on Saturday. Nathan Ake is not fully fit so is replaced by Eric Garcia at the back, and Ilkay Gundoghan makes his first start of the season, coming in for Phil Foden in midfield.

Sergio Aguero continues up front after playing his first 65 minutes of the season against the Gunners.

Foden is among the substitutes, along with John Stones, Fernandinho and the fit again Oleg Zinchenko but Guardiola appears short of numbers as he also has two goalkeepers - Zack Steffen and Scott Carson - on the bench.

Man City XI: Ederson, Walker, Dias, Garcia, Cancelo, Rodri, Gundogan, Bernardo, Mahrez, Sterling, Aguero

Image source, BBC Sport

New City centre-half Ruben Dias comes up against his partner for Portugal at the back tonight, in the shape of the vastly experienced Pepe.

The 37-year-old, a three-time Champions League winner with Real Madrid, is joined in the Porto defence by Malang Sarr, who is on a season-long loan from Chelsea. Felipe Anderson and Marko Grujic, who also joined recently from West Ham and Liverpool on identical deals, are on the bench

Porto XI: Marchesin, Pepe, Diaz, Uribe, Marega, Sanusi, Corona, Mbemba, Oliveira, Sarr, Vieira

Image source, BBC Sport

Karim Benzema is on for Real Madrid, tasked with helping kick start the comeback. He replaces Rodrygo.

Back under way.

BIG performance needed by Real Madrid.

Meanwhile, Manchester City make two changes for the visit of Porto with Ilkay Gundogan and Eric Garcia coming in for Phil Foden and Nathan Ake.

Full team news to follow.

Image source, Getty Images

Ajax manager Erik Ten Hag says Virgil van Dijk's absence won't change how his side approach tonight's game.

"At the end of the day it is about who is still playing. It's not going to be a different Liverpool, they always play the same," said the Dutchman.

"The quality of Man A can switch to Man B, the whole team won't change because Virgil Van Dijk isn't present.

"They are currently the best team in the world, if you win the Champions League and Premier League within two years you are a strong contender for the Champions League title."

Liverpool begin life without centre-back Virgil van Dijk, and with Joel Matip also ruled out, versatile Brazilian Fabinho starts in defence alongside Joe Gomez.

Teenager Curtis Jones is handed a Champions League debut in midfield, alongside James Milner, making his first start since July.

Captain Jordan Henderson misses out, while Georginio Wijnaldum comes in for the injured Thiago Alcantara.

Liverpool XI: Adrian, Alexander-Arnold, Gomez, Fabinho, Robertson, Milner, Wijnaldum, Jones, Salah, Firmino, Mane

Subs: Kelleher, Jaros, Henderson, Minamino, Jota, Shaqiri, Origi, R Williams, Cain, N Williams

Image source, BBC Sport

Former Manchester United defender Daley Blind starts for Ajax, alongside ex-Southampton midfielder Dusan Tadic.

Ajax XI: Onana, Schuurs, Klaassen, Neres, Gravenberch, Tadic, Mazraoui, Blind, Kudus, Martinez, Tagliafico

Denise Hardy: Real Madrid need to channel their inner West Ham in the 2nd half.

Pieter: I can't believe this.

Elsewhere, Salzburg struck just before the break through Dominik Szoboszlai.

All square in that one.

A bit of late pressure from Real Madrid as they try and claw something back but the visitors hold them at bay before the whistle goes for half time.

An incredible first half.

Yes, you are reading that scoreline correctly. Real Madrid, the 13-times European champions - are losing 3-0 at home to Shaktar.

It's not even half time.

Casemiro nods a ball down into the middle of the Shakhtar box, he's looking for Rodrygo but the visitors defend well again.

Dodo cuts out a ball down the flank aimed at Marco Asensio and there is applause from the Shakhtar bench. The visitors are defending well as they look to get to half time with a two-goal lead.

Frustration is etched on Zinedine Zidane's face as his side continue to struggle to get into this game.

Dennis Ethan: Real Madrid are missing Gareth Bale so massively, who is golfing right now.

The underdog tag is certainly working for Shakhtar because every player is giving their all to upset the odds. A goal ahead and they are on the attack again looking for more.