Arsenal have no new injury concerns arising from their Europa League draw at Benfica on Thursday.

Kieran Tierney could start after returning from a month-long injury as a substitute during that game, but Thomas Partey remains a fitness doubt.

Manchester City's Premier League top scorer Ilkay Gundogan has returned to training after missing the win at Everton with a groin issue.

Nathan Ake is their only other absentee.

Mark Lawrenson
BBC football expert

West Ham are flying and are up in fifth place, while Tottenham have been pretty ordinary, or worse, recently.

On form you would have to go with the Hammers every time but Harry Kane is back for Spurs now and a moment or two of quality from him could make all the difference - they really need it too.

Prediction: 1-2

Lawro's full predictions v Architects frontman Sam Carter

Jadon Sancho and Erling Braut Haaland both scored as Borussia Dortmund claimed an emphatic derby win at Bundesliga strugglers Schalke yesterday.

The result marks a return to form for Dortmund, who had won just one of their previous six matches in the German top flight.

England winger Sancho opened the scoring and Haaland doubled the visitors' lead before half-time.

Read the report here.

Image source, Getty Images

West Ham have lost just once in 10 Premier League matches, winning six and drawing three.

Their tally of 42 points is their best after 24 games of a top-flight season since they recorded 48 in 1985-86 and eventually finished third.

Meanwhile, Tottenham have lost four of their past five league games, as many as in their previous 28, and have won just once in seven top-flight away fixtures (D3, L3).

Spurs have also conceded eight goals in their past two games...

Image source, BBC Sport

Manchester United will assess the fitness of Edinson Cavani and Donnie van de Beek, who were both left out of the Europa League squad on Thursday with muscular injuries.

Scott McTominay is a doubt after he was substituted at Real Sociedad, while Paul Pogba remains out.

Newcastle United defender Federico Fernandez is back in training and could feature against Wolves next weekend.

Jeff Hendrick returns from suspension but Callum Wilson is still sidelined.

Simon Stone
BBC Sport reporter

Nicky Butt and Mark Dempsey will join Ole Gunnar Solskjaer on the bench this evening for Manchester United's game at home to Newcastle United due to some of the coaching staff having to self isolate.

Another goal or assist later today for Leicester's Jamie Vardy would ensure he became only the sixth player to be directly involved in 100 Premier League goals since turning 30 years old. He has 81 goals and 18 assists.

Image source, Getty Images

Aston Villa full-back Matty Cash has a hamstring strain which will keep him out for at least three weeks.

Ahmed Elmohamady will most likely deputise in only his second league start of the season.

Timothy Castagne is fit for Leicester after a five-match absence with a hamstring problem but Ayoze Perez is sidelined with a knee injury.

Wes Morgan remains out, along with long-term absentees James Justin, Dennis Praet and Wesley Fofana.

Phil McNulty
BBC Sport chief football writer

As Everton enjoyed a long-awaited victory on the turf of their great rivals Liverpool yesterday, manager Carlo Ancelotti beamed broadly and grabbed his players in bear hugs.

Twenty-two years have passed since their last win at Anfield. In that period, Ancelotti has won the Champions League three times, the Fifa Club World Cup twice, and league titles in Italy, England, France and Germany.

There was no silverware on offer at Anfield on Saturday, but his reaction at the final whistle showed he knew just how big a cause for Everton celebration this was.

Read more here.

West Ham v Tottenham (12:00 GMT)

Aston Villa v Leicester City (14:05 GMT)

Arsenal v Manchester City (16:30 GMT)

Manchester United v Newcastle (19:00 GMT)

West Ham boss David Moyes makes two changes from the 3-0 win over Sheffield United.

Pablo Fornals and Michail Antonio return to the side, replacing Ben Johnson and Manuel Lanzini.

Fabian Balbuena is on the bench after recovering from a calf injury.

West Ham XI: Fabianski, Cresswell, Coufal, Lingard, Dawson, Fornals, Bowen, Diop, Soucek, Antonio, Rice

Image source, BBC Sport

Jose Mourinho makes seven changes to the Tottenham side who recorded a win over Wolfsberger in Thursday's Europa League.

Sergio Reguilon starts despite being a doubt with a muscle injury.

Davinson Sanchez, Pierre-Emile Hojbjerg, Harry Kane, Erik Lamela, Japhet Tanganga and Tanguy Ndombele all return to the starting XI.

Gareth Bale, Harry Winks, Dele Alli and Moussa Sissoko are among those to drop to the bench.

Tottenham XI: Lloris, Reguilon, Hojbjerg, Sanchez, Son, Kane, Lamela, Dier, Tanganga, Moura, Ndombele

Image source, BBC Sport

Morning!

We've got a busy day in the Premier League. There are four matches taking place - the first kicking off in an hour.

Four of the teams in the top five are in action, as well as a tasty fixture between Arsenal and Manchester City later this afternoon.

Image source, Getty Images