A reminder of the teams...published at 17:58 British Summer Time 11 May 2021
Man Utd v Leicester (18:00 BST)
Man City win Premier League title
Man Utd 1-2 Leicester: Teenager Thomas gives Foxes lead with stunning volley, Greenwood's tidy finish levels, Soyuncu heads in to restore lead
Foxes will strengthen top-four place with win
Southampton 3-1 Crystal Palace: Benteke scrambles home early opener, Ings turn and finish to level
Forster saves Milivojevic penalty, Adams strikes for Saints lead & Ings adds his second
Alex Bysouth
Man Utd v Leicester (18:00 BST)
Man Utd v Leicester (18:00 BST)
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Man Utd v Leicester (18:00BST)
Simon Stone
BBC Sport at Old Trafford
Anthony Elanga has been tipped for big things since he first joined Manchester United's academy in 2018.
He is the reigning United academy player of the year and a Sweden Under-19 international.
Be interesting how he adapts to this sudden elevation.
Man Utd v Leicester (18:00 BST)
Things are looking bright at Old Trafford...
With their Champions League place confirmed, this the first time the Red Devils have recorded consecutive top-four finishes in the Premier League since Sir Alex Ferguson retired as manager.
Ole Gunnar Solskjaer's side are also aiming to win five Premier League home games in a row for the first time since March 2018 under Jose Mourinho.
Man Utd v Leicester (18:00 BST)
Mark Lawrenson
BBC football expert
I wonder how the Leicester players reacted when they found out how Manchester United will line-up tonight?
I know what Lawro thought - he changed his prediction from a 2-0 United win to a 1-1 draw when he saw the side Ole Gunnar Solskjaer has picked.
Man Utd v Leicester (18:00 BST)
Brendan Rodgers' outfit could become only the fourth side in Premier League history to win away at Manchester United and Manchester City in a single season after Everton in 1992-93, Middlesbrough in 2003-04 and Liverpool in the 2008-09 campaign.
Man Utd v Leicester (18:00 BST)
Man Utd v Leicester (18:00 BST)
Leicester City
Leicester boss Brendan Rodgers: "Playing against the big teams you have to have a big energy and big attitude in the game. You have to be able to press, run.
"It doesn't matter what team you put out there is always a pressure to win. Ole has the right to pick whatever team he wants to pick - they have qualified for Champions League and are in the Europa League final."
Man Utd v Leicester (18:00 BST)
Relegation is sorted, the league is almost won, so the only thing to really play for - apart from pride - is a place in the top four. Here's a nice indicator of how the race for a Champions League spot is going...
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Man Utd v Leicester (18:00 BST)
This lad is in some serious form at the moment... Kelechi Iheanacho has scored 15 goals in his past 16 appearances in all competitions, and could help former side Manchester City out by continuing that streak this evening.
Man Utd v Leicester (18:00 BST)
Man Utd v Leicester (18:00 BST)
Manchester United
More from Solskjaer, on Anthony Elanga making his debut: "He is a good boy, has a had a couple of injuries that has probably delayed this debut, he is one I am looking forward to seeing - he has pace, is direct and is a goal threat."
Man Utd v Leicester (18:00BST)
Simon Stone
BBC Sport
Manchester United manager Ole Gunnar Solskjaer has provided an update on Harry Maguire, who suffered an ankle injury at Aston Villa on Sunday and misses his first Premier League game of the season tonight.
The news is good - or at least not as bad as it could be.
"There's no fracture," said Solskjaer. "There is ligament damage but hopefully we'll see him again this season and hopefully he will be ready for the final."
That is also good news for England boss Gareth Southgate.
United play Villarreal in the Europa League final in Gdansk on 26 May.
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Tom Lawrence: Klopp got absolutely slated for playing kids against Aston Villa in the League Cup when we had a game less than 24 hours later on another continent... Where's that energy for Ole tonight?
Harrison Short: Ole fielding a weak team to let Leicester win so Liverpool don’t get Top 4 is legendary behaviour
Daniel Quirk: Is it bad that I wouldn’t care if we got beat tonight? Sorry Liverpool
Man Utd v Leicester (18:00 BST)
Leicester have only won two of their 29 Premier League fixtures against Manchester United.
The Foxes' solitary win in their past 22 top-flight visits to Old Trafford came on 31 January 1998, when Tony Cottee scored the only goal.
The Red Devils have scored in the subsequent 23 league matches between the sides since that defeat, which is their longest Premier League scoring streak against a single opponent.
Man Utd v Leicester (18:00 BST)
Man Utd v Leicester (18:00 BST)
Speaking to former colleagues and coaches of Dean Henderson, one word comes up over and over again: confidence. Throughout his loan spells, from Stockport County to Sheffield United, he never doubted he was destined to play at the highest level.
The self-belief needed to be a top goalkeeper typically comes with experience, but the Manchester United and England man relished defying expectations. His first taste of senior football was with Stockport in the National League North as a little-known 18-year-old.
"He fitted in really well. He came across as a confident goalkeeper without being arrogant. He fully believed in his own ability," remembers John Marsden, who was a forward at Stockport at the time. "From very early on, he was always saying he would one day be Manchester United's first-choice goalkeeper."
Telling a dressing room full of established players he would follow in the footsteps of legends like Peter Schmeichel and Edwin van der Sar was a bold strategy. Henderson's irrepressible ambition risked alienating his new team-mates, but they admired him for it.
Sean Cole looks into the man battling with David de Gea for the number one spot at Old Trafford.
Man Utd v Leicester (18:00BST)
Simon Stone
BBC Sport at Old Trafford
David de Gea starts his first Premier League game since he returned to Spain for the birth of his first child and lost his spot as number one to Dean Henderson.
I have been told Manchester United are trying to persuade Tom Heaton to return to the club where he started his career.
That, in theory, is as a replacement for Sergio Romero and Lee Grant, although as neither of those two actually play, the feeling is it is a sign De Gea will be leaving in the summer.
If that is the case, his final appearance could come against Villarreal in the Europa League final on 26 May.
Man Utd v Leicester (18:00 BST)
There was a great interview in the Guardian on Monday, external with Sir Alex Ferguson talking to Donald McRae, in which he talks about his tough start to life as Manchester United boss. The Scot believes the fans were the reason he managed to turn things around...
"I just needed a break. But, the whole of December 1989, I never won a game. We lost every game or drew. So the FA Cup [third round] draw comes out. Nottingham Forest, away. God! Arguably the best cup team in the country under Brian Clough," said the former United boss.
“We went there and supporters today would find it hard to name the team because we had so many injuries. But you know who won the game? The fans. Their defiance was unbelievable. Right through the game they chanted and urged us on and we won. It changed everything.”
Man Utd v Leicester (18:00BST)
Simon Stone
BBC Sport at Old Trafford
I was here 10 days ago when there were lots of protesters and not much in the way of security and police.
Now the situation has been reversed.
There were hardly any fans outside the front of the stadium an hour ago and none at the back when I drove into the car park.
Huge numbers of police vans are parked up, security staff are manning fences before fences and there are more photographers than people to keep out.
It should at least mean we get a trouble-free game and the only people on the pitch will be players.