Postpublished at 21:48 British Summer Time 21 September 2021
Advantage Leeds after the first set of penalties at Craven Cottage. Rodrigo scores before Josh Onomah hits the bar for the home side. 0-1
QPR beat Premier League Everton on penalties after match ends 2-2
Championship Stoke beat Premier League Watford 3-1
Leeds beat Fulham on penalties after goalless draw
Holders Man City thrash Wycombe 6-1 - De Bruyne, Mahrez (2), Foden, Torres & Palmer
Minamino (2) & Origi give Liverpool 3-0 win at Norwich, Canaries miss penalty
Southampton beat Sheff Utd on penalties after game ends 2-2
Burnley beat Rochdale 4-1 after falling behind - Rodriguez scores all four
Brentford hit seven past Oldham
Phil Dawkes, Shamoon Hafez and Emlyn Begley
Advantage Leeds after the first set of penalties at Craven Cottage. Rodrigo scores before Josh Onomah hits the bar for the home side. 0-1
Ben Godfrey...MISSES for Everton! Seny Dieng saves it but WAIT!!
The goalkeeper is adjudged to be off his line and it has to be retaken.
Southampton lead Sheffield United 2-1 after Rhian Brewster's kick is saved by Fraser Forster.
Sub Stephen Duke-McKenna steps up for QPR...and scores!
What a penalty from Abdoulaye Doucoure, into the top corner.
QPR 5-6 Everton
QPR 5-5 Everton.
Anthony Gordon's take is levelled up by Albert Adomah.
Sudden death!
Southampton and Sheffield United score their first penalties, James Ward-Prowse and Oliver Norwood.
QPR 4-4 Everton on penalties now, Chris Willock squeezes in via the post.
The pressure pens now.
QPR 3-3 Everton on penalties now.
Demarai Gray steps up and the in-form winger confidently converts.
QPR and Everton are level after two penalties each.
Preston 4-1 Cheltenham
A comfortable win in the end for Championship Preston against League One Cheltenham.
Fulham 0-0 Leeds
Penalties it is then.
Fulham 0-0 Leeds
Late chances!
Charlie Cresswell wins a big header in the box from a free-kick for Leeds to send the ball back across goal and Rodrigo is inches from making contact with a header of his own.
Fulham are quickly down the other end and Rodrigo Muniz volleys over from a cross from the right.
Emil Riis Jakobsen (90+3 mins)
Emil Riis Jakobsen bags a fourth for Preston in injury time.
Sheffield Utd 2-2 Southampton
This goes to penalties as well.
Watford 1-3 Stoke
The big shock of the night!
Championship side Stoke score twice in the last 10 minutes to send out Premier League Watford.
Fulham 0-0 Leeds
Into four minutes of added time. Michael Hector looks to inflict the killer blow but fires his effort wide from an angle.
Burnley 4-1 Rochdale
Jay Rodriguez 4-1 Rochdale
Wigan 0-2 Sunderland
The Black Cats go through after sending out their fellow League One side.
Brentford 7-0 Oldham
Marcus Forss got four as Premier League Brentford battered the EFL's bottom club Oldham.