Postpublished at 15:31 Greenwich Mean Time 8 January 2022
Leicester 2-1 Watford
The first of Leicester's two goals so far - from the spot by Youri Tielemans.
Everton, Southampton and Plymouth through after extra time in day's late games
League One Cambridge Utd stun Newcastle - arguably day's biggest shock
National League North Kidderminster bridge four-division gap to beat Reading
National League Boreham Wood beat AFC Wimbledon
Championship side Huddersfield win 2-1 at Burnley
Every goal across the weekend available on BBC Sport app
Michael Emons, Gary Rose and Harry Poole
Leicester 2-1 Watford
The first of Leicester's two goals so far - from the spot by Youri Tielemans.
Paul Coutts (29 mins, pen - Bristol Rovers)
Bristol Rovers were only behind for 10 minutes and have now equalised thanks to Paul Coutts' penalty against his former side.
It came after home goalkeeper David Cornell had brought down Antony Evans in the penalty area and Coutts kept his cool to send Cornell the wrong way and the visitors are level.
West Brom 0-0 Brighton
Danny Welbeck's chance for Brighton still the best of the half so far.
But the visitors are forced into an early change here. Enock Mwepu is replaced by Alexis Mac Allister.
Peterborough 1-0 Bristol Rovers
Mads Andersen
Barnsley lead!
And it's the skipper.
Mads Andersen gets up to meet Callum Styles' free-kick delievery and heads into the corner.
Joao Pedro (26 mins)
Oh, hello!
Literally seconds after Leicester make it 2-0, Joao Pedro comes back with an immediate response from Watford.
Leicester's defence are all over the shop. Pedro bundles through in the box and coolly dinks it over Danny Ward. Great finish!
Game on.
Marcus Forss (26 mins)
The Premier League side have the breakthrough!
Marcus Forss completes a swift counter attack with a cool finish, following a driving run through the middle by Mads Bidstrup.
Brentford have been much better in the last few minutes.
Newcastle 0-0 Cambridge
Good save!
Allan Saint-Maximin strides into the Cambridge half, drives at the defence and then picks out Jacob Murphy.
He looks to feed one into the bottom corner, but goalkeeper Dimitar Mitov gets down well.
Kidderminster Harriers 0-0 Reading
Kidderminster are more than holding their own against their Championship opponents although they are yet to manage a shot on target. Sam Austin has had a shot blocked, but that's about it so far for the home side. The hosts are looking lively, however.
James Maddison (25 mins)
It's a simple, but effective goal from Leicester, who have doubled their lead at the King Power.
It's played into Ademola Lookman. He takes a touch, turns and slides it through to James Maddison, who makes a good run in behind the centre-back.
Maddison slips it first time past Daniel Bachmann and into the bottom left corner.
Port Vale 0-0 Brentford
Tom Conlon whips a free-kick into the Brentford box from the left, but the Bees defence deal with it.
The danger hasn't gone, but a cross back in from the right fails to find a team-mate. Vale Park is bouncing!
Newcastle 0-0 Cambridge
Jonathan Woodgate
Former England defender on BBC Radio 5 Live
Technically, Cambridge are very good footballers.
Newcastle are working on each side of the pitch but I'm concerned about them on the counter attack. They are leaving some gaps open and they haven't really created anything yet.
Leicester City 1-0 Watford
Harvey Barnes gets in behind the Watford defence on the left but nobody is there to get on the end of his cut-back across the six-yard area.
West Brom 0-0 Brighton
Big chance for Danny Welbeck.
He's played through and only has the keeper to beat but David Button pulls off a decent save.
Newcastle 0-0 Cambridge
Slick football from Newcastle as they cut through the Cambridge defence with some neat, quick passing but Joelinton's low ball across the six-yard box just evades Allan Saint-Maximin.
Port Vale 0-0 Brentford
Brentford should be ahead!
Port Vale fail to deal with a long throw into the box and Marcus Forss' shot is knocked on by Yoanne Wissa - but Vale goalkeeper Aidan Stone is able to get down to it just in time.
Sammie Szmodics (19 mins)
The Championship side take the lead. Oliver Norburn is involved in the build-up with a fine pass forwards.
But it is a big error from away goalkeeper James Belshaw, who had rushed out of his penalty area and tried to clear it, but completely missed the ball and that enabled Sammie Szmodics a simple task to tap the ball into an unguarded net.
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Christopher: VAR should be at all 32 ties or at none, it's not fair that the Premier League grounds can use it but no one else can.
Leicester City 1-0 Watford
Jannik Vestergaard gives it away and Watford suddenly have a two-on-one break. Joao Pedro has it on the right but he can't pick out Ashley Fletcher in the middle.
From the corner, Moussa Sissoko's shot is over the bar.
Boreham Wood 1-0 AFC Wimbledon
It has been a dream start for Boreham Wood but they are having some defending to do at the moment with AFC Wimbledon pressing for an equaliser.