Craig Dawson's first touch could be a goal as he gets into the area ready for a free kick, but Hendrik Van Crombrugge plucks the ball out of the air ahead of the defender.

Emma Sanders
BBC Sport at Old Trafford

The two biggest chances so far have fallen to Marcus Rashford, who scored twice against Omonia last week. He is making all the right runs but that was a huge opportunity to put United 1-0 up. He just hit it straight at the keeper. Half of the stadium were on their feet as it was played through expecting a goal.

Marcus Rashford is played in by Cristiano Ronaldo and only has goalkeeper Francis Uzoho to beat.

Rashford strikes with his left foot, but Uzoho had sped off his line, closed the angle down well and produces another fine save to keep it 0-0.

Image source, Getty Images

Yep, here comes that change with David Moyes unwilling to take any risks. Craig Dawson is on for Angelo Ogbonna, who is able to walk off, so hopefully nothing too serious.

Antony tries to use his pace to get around the outside of his marker, but can't get a cross in.

United keep the move alive with Casemiro finding Tyrell Malacia and his delivery is aimed towards Bruno Fernandes but the ball sails over his head.

Image source, Getty Images

David Moyes looked concerned because Angelo Ogbonna is down on the ground and receiving treatment. Craig Dawson is warming up and looks to me like he is going to have to come on.

Wales international right-back Adam Matthews, who lists Cardiff, Celtic, Sunderland, Bristol City and Charlton among his previous clubs, gets some space down the right flank for Omonia.

There isn't much support up with him, but Matthews' cross from the right is a disappointing one anyway and United easily clear.

Emma Sanders
BBC Sport at Old Trafford

Neil Lennon has just waved his arms in the air in frustration. United are winning every second ball in midfield at the moment.

Simon Stone
BBC Sport at the London Stadium

West Ham had a free-kick a few minutes ago, which Aaron Cresswell and Said Benrahma stood over. Cresswell took it and it went over the bar.

The same two players stood over that one and Cresswell was the decoy run.

I'm not sure the Anderlecht wall or the keeper covered themselves in glory but it was a decent enough hit from the Algerian.

West Ham edging towards the knockout round - and possibly straight into the last 16 - with two games to spare.

Image source, Getty Images

Anderlecht look to respond as Fabio Silva, who is on loan from Wolves, sees a gap between West Ham's centre-backs and lets fly but it is straight at Alphonse Areola.

Bruno Fernandes, close to the right touchline, plays a low cross first time into a dangerous area, but it is just ahead of his Portugal team-mate Cristiano Ronaldo.

Omonia Nicosia, as manager Neil Lennon probably expected, hanging on a bit already.

Image source, Getty Images

Lovely footwork by Said Benrahma draws a foul and West Ham have a free kick in a dangerous position, quite central and 25 yards from goal...

Manchester United hogging the ball...and hogging the stats. Still goalless though.

Image source, .

Jarrod Bowen is fouled by Kristian Arnstad, who picks up the first booking of a game that has been pretty quiet so far.

Cristiano Ronaldo, whose last goal was his 700th in club football, gets a chance on his left foot and he goes for the near post but can only hit the side netting.

The net ripples and those on the opposite side of the ground think it's gone in, but it hasn't.

Image source, Getty Images

Emma Sanders
BBC Sport at Old Trafford

United, as expected, are controlling things at the moment and Fred has been heavily involved. It's a good opportunity for him tonight alongside Casemiro to show what they can do as a midfield pairing. Marcus Rashford is also looking very sharp.

Simon Stone
BBC Sport at the London Stadium

There was an impressive light show before kick-off.

Now it is up to West Ham's players to light up the London Stadium.

Lucas Paqueta is playing in a false nine role, with Said Benrahma and Jarrod Bowen at either side.

Vladimir Coufal and Emerson are supplying with from the wing-back slots.

Backed by a boisterous home crowd, West Ham are dominating possession in these early stages.

Anderlecht are playing with four at the back to try and nullify the Hammers' attacking players, and there's not many spaces for the likes of Jarrod Bowen and Said Benrahma to cause problems just yet.