Eeek! Jorginho is at fault in midfield as Sporting win possession then break.

Pedro Goncalves cuts inside onto his right foot and has space but he curls it well wide. He falls to the ground in frustration. What a chance!

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First attack from Arsenal. Reiss Nelson chips it in from the left but Gabriel Martinelli is stretching as his header drops kindly for the keeper.

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Gabriel Martinelli's pass is a little loose in the middle but Oleksandr Zinchenko wins it back immediately.

Sporting have settled into an organised shape, Arsenal are already controlling things.

A first touch for Arsenal debutant Jakub Kiwior as they pass it around the back before Ben White tries to catch out Sporting with a ball over the top for Bukayo Saka. He's overcooked it though.

Image source, Reuters

Off we go in Portugal as Arsenal get their last-16 tie under way, while West Ham are also kicking off in Cyprus.

AEK Larnaca XI: Piric, Tomovic, Casas, Milicevic, Englezou,, Sanjurjo, Ledes, Rosales, Jakolis, Mamas, Lopes.

West Ham XI: Areola, Kehrer, Zouma, Aguerd, Cresswell, Downes, Rice, Benrahma, Lanzini, Fornals, Antonio.

Arsenal XI: Turner, Zinchenko, Kiwior, Saliba, White, Xhaka, Jorginho, Vieira, Nelson, Martinelli, Saka.

Sporting Lisbon XI: Adan, Inacio, Coates, St. Juste, Reis, Pote, Morita, Esgaio, Edwards, Trincao, Paulinho.

Arsenal

Arsenal manager Mikel Arteta speaking to BT Sport: "Emotionally it was really intense [after the Bournemouth win], it gave us a big boost to win and now it is a different competition. We prepared really well but it is a tough opponent."

On what he told the squad after Saturday's win: "They made a lot of people happy and experience a very different end of the game that we expected two seconds before the final whistle."

On whether it is realistic to compete in Europe and the league: "That is our aim in every competition. At a club like Arsenal, you have to aim to win it and be your best every day.

"We made six changes because we have lot of issues with players that we have missed. Some of them aren't even here but that is why we have built a good squad."

On starting Jakub Kiwior: "Hopefully he will take it he has been training really well, and he has to start eventually. I have full faith in him.

On whether Gabriel Martinelli will start through the middle: "We will see."

West Ham United

West Ham manager David Moyes speaking to BT Sport: "Being in Europe after Christmas time was always a positive. Last year we did it and got to the semi-finals and I am hoping we can go one step further.

"Tonight we are in a small stadium, we played in Seville last year, we played in Lyon, it is a big thrill coming to any European game. It is a big thing for managers and players. This is a competition we have been really looking forward to."

Former England goalkeeper Rachel Brown-Finnis on BT Sport: "I think Mikel Arteta has been patient with Gabriel Martinelli and it is paying off.

Playing off the left-hand side, he scores goals. His movement and understanding between other players at just 21 is top quality.

BBC Radio 5 Live

There's full radio commentary from Old Trafford for Manchester United's match later, with build-up kicking off from 19:00 GMT.

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Sporting Lisbon, who sit fourth Portugal's Primeira Liga, are gunning for a north London double.

Their European campaign actually started in the Champions League and although they failed to make it through to the knockout stage, they beat Tottenham 2-0 in Lisbon on 13 September.

In fact Ruben Amorim's side took four points off Spurs in two group games after a 1-1 draw at Tottenham Hotspur Stadium on 26 October.

Reiss Nelson has only featured once for Arsenal since November...

But he scored that dramatic late winner against Bournemouth at the weekend. Will he have another impact tonight?

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Former Arsenal defender Martin Keown on BT Sport: "I think Mikel Arteta has picked a really good team tonight. There is enough strength in there, even with the six changes. They still look strong."

Image source, Getty Images

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Paris St-Germain's 11th consecutive attempt at winning the Champions League ended in more misery - so is it time for them to "rip it all up" and start again?

Bayern Munich dumped them out in the first knockout round 3-0 on aggregate, with Wednesday's 2-0 win in Germany sealing the victory.

A team with the two most expensive players of all time - Neymar, who was injured for the second leg, and Kylian Mbappe - as well as arguably the greatest player in the history of football, Lionel Messi, failed to score over 180 minutes.

Read more here.

West Ham United

West Ham finished the group stages with a perfect record but have struggled in the Premier League this season and are currently just one point above the relegation zone.

David Moyes believes the Europa Conference League is an important competition however, citing Roma's success under manager Jose Mourinho last year.

"To try to win any trophy as a football manager, or a player - very few get that big opportunity to do so," he added.

"Jose Mourinho showed you how much it mattered to him and he is a serial winner.

"We wanted desperately to win the Europa League but we couldn't quite get past the semi-finals."

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West Ham are backing manager David Moyes but it is hoped results "will keep on improving", says vice-chair Karren Brady.

"I can't put any pressure on David Moyes because he puts enough on himself," Brady told BBC Radio London.

"The really important thing is for everyone to stick together to be really focused, understand what the issues are.

"It's been a disappointing season. After two great seasons and the success we had in Europe, things haven't gone the way we wanted.

"We spent an extraordinarily large amount of money in the summer. Undoubtedly, it takes people time to settle in and create a new way of playing with such a lot of new players."

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Arsenal have kept a clean sheet in four of their last five games in the Europa League.

However, each of the last five goals they have conceded in the competition have come in away games.

Phil McNulty
BBC Sport chief football writer

When the final whistle sounded in the goalless draw that confirmed Tottenham exit at the last-16 stage of the Champions League, every sight and sound screamed the beginning of the end of manager Antonio Conte's 16-month reign.

Spurs fans reacted furiously, the body language reflected a broken team, the empty seats illustrated the brutal reality of the discontent that bubbled beneath the surface throughout what should have been a full-blooded and furious attempt to rescue their European aspirations against AC Milan.

The ramifications of this defeat over two legs may be felt far and wide at Spurs, but it was the manner of the performance that will bring justifiable criticism down on Conte's head, his eventual exit now surely a formality, whether it comes at the end of the season or before.

There is no indication he is willing to renew a contract that expires at the end of this campaign, and just as significantly no sign that Spurs are desperate for him to sign one.

It just seems a matter of time before Conte leaves.

Read more here.

Image source, BBC Sport/Getty Images

Image source, Getty Images

Sporting have progressed from each of their previous six ties against English sides in the knockout stages of the Europa League, with all six coming against different teams.

Arsenal, meanwhile, are unbeaten in six previous meetings with Portuguese opponents in the Europa League.