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Bristol centre Jack Tovey and wing Charlie Amesbury will make their first starts of the season against Saracens.

Samoa prop Anthony Perenise comes in, as the third of Andy Robinson's three changes from his side's loss to Exeter.

Bristol are without nine injured first-team squad players, including scrum-half Martin Roberts (dislocated elbow) and versatile back Gavin Henson (dead leg).

Saracens make six changes from the 17-10 loss at Harlequins, as England lock George Kruis returns from a back injury and Ben Spencer comes in at scrum-half.

Matt Gallagher makes his debut on the wing, while Jamie George and Schalk Burger are named in the forward pack.

Full-back Alex Goode has a knee injury and is not risked, while fly-half Owen Farrell (back) is still out and winger Chris Ashton is banned until 19 December.

Bristol: Williams; Edwards, Tovey, Hurrell, Amesbury; T Pisi, Cliff; Traynor, McMillan, Perenise, Phillips, Sorenson, Fisher, Lam (capt), Crane.

Replacements: Crumpton, Bevington, Cortes, Joyce, Eadie, Williams, Jarvis, Wallace.

Saracens: Wyles; Ellery, Tompkins, Barritt (capt), Gallagher; Lozowski, Spencer; M Vunipola, George, De Plessis, Itoje, Kruis, Wray, Burger, B Vunipola.

Replacements: Spurling, Barrington, Figallo, Hamilton, Rhodes, Wigglesworth, Bosch, Perkins.

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England flanker Calum Clark is set to make his first Premiership appearance since May 2015 for Northampton following a shoulder injury.

Scrum-half Lee Dickson misses out through injury.

England winger Jack Nowell features on the Exeter bench for the first time this season after thumb surgery.

Ollie Devoto returns at centre in place of Sam Hill as one of five changes, while Ben Moon and Jack Yeandle start in the front row.

Geoff Parling is preferred at lock to Damian Welch and Kai Horstmann starts at flanker.

Northampton: Foden (capt); K Pisi, G Pisi, Mallinder, North; Myler, Groom; Waller, Haywood, Brookes, Lawes, Paterson, Gibson, Clark, Picamoles.

Replacements: Clare, Ma'afu, Hill, Dickinson, Harrison, Kessell, Hutchinson, Tuala.

Exeter: Turner; Woodburn, Devoto, Slade, Whitten; Steenson, Chudley; Mood, Yeandle (capt), Holmes, Lees, Parling, Dennis, Horstmann, Waldrom.

Replacements: Cowan-Dickie, Hepburn, Williams, Welch, White, Lewis, Hill, Nowell.

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As far as this evening's agenda goes, here's what we've got to look forward to...

(Both 19:45 kick-off) 

• Bristol v Saracens 
• Northampton v Exeter

And we'll have full live text and local radio commentary on both on this very page, so don't you move a muscle.

Now then, let's run through some team news...

After a frantic fourth round of Premiership fixtures packed full of surprises, it definitely sort of feels like the English rugby union season is cranking into gear at last.

We have our early-season pacesetters, Wasps.

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We have our slowly-adapting - but still winless - strugglers, Bristol.

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And we have a whole heap of intrigue in between, too - the end of the champions' unbeaten start, for instance.

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The question, now, is what will we have next?