Image source, Rex Features

Harlequins are unchanged from their Challenge Cup win over Timisoara Saracens, after Chris Robshaw failed a late fitness test earlier today.

England prop Joe Marler makes his 100th Premiership appearance for Quins.

Harlequins: Brown; Yarde, Marchant, Roberts, Visser; Jackson, Care (capt); Marler, Buchanan, Sinckler, Merrick, Matthews, Chisholm, Wallace, Clifford.

Replacements: Ward, Evans, Collier, South, Naoupu, Dickson, Swiel, Alofa.

Image source, Rex

These two sides drew 39-39 in the corresponding fixture last season, sharing 10 tries in a genuine classic.

There was drama right to the end, as Nick Evans missed a last-minute drop-goal that would have won it for Quins.

If we get half as good a game as that today, we'll be in for a real treat!

Image source, Getty Images

Good afternoon! My word, are you in for a treat this afternoon.

We've got festive Premiership rugby from Twickenham to bring you, with some 70,000 people expected at the home of rugby!

And there is plenty at stake in the top-flight standings, with two teams both trying to get back into the top six and close the gap between themselves and the teams in the play-off places.

Kick-off between Harlequins and the visitors Gloucester is coming up at 16:00 GMT.