Postpublished at 16:09 British Summer Time 4 June 2021
*Williams 5-4 Collins
Ooh, a double fault from Serena Williams.
And another!
0-30 from out of nowhere.
Greece's Stefanos Tsitsipas beats American John Isner 5-7 6-3 7-6 6-1 to reach round four
Use audio icon at top of page to listen to Radio 5 Live commentary (UK only)
Serena Williams beats fellow American Danielle Collins 6-4 6-4 to reach fourth round
Men's second seed Daniil Medvedev joins Alexander Zverev in fourth round
Michael Beardmore
*Williams 5-4 Collins
Ooh, a double fault from Serena Williams.
And another!
0-30 from out of nowhere.
Medvedev 6-4 6-2 Opelka*
Meanwhile, plenty for Reilly Opelka to ponder as Daniil Medvedev swiftly wraps up the second set 6-2 on Court Suzanne-Lenglen.
Remember - before this week the Russian had never got past the first round at Roland Garros. Welcome to the second week?
Laura Robson
Former British number one
Danielle Collins is such a good competitor and she gets so fired up.
You see her fist-pumping right at her opponents - I love it!
Williams 5-4 Collins*
A nice backhand into an empty court saves the set point and now Collins has advantage after Serena Williams hits the net.
Collins is beginning to get pumped up now and she pulls out an ace to make Serena serve for the set.
Williams 5-3 Collins*
But a Collins forehand goes long on the next point...
Williams 5-3 Collins*
An unbelievable backhand down the line keeps Danielle Collins from falling 0-40 down on serve.
Serena Williams is looking and looking at the line. But it was in.
Another similar shot brings Collins level at 30-30.
*Williams 5-3 Collins
Collins battles back to 40-30 but a lovely serve-and-volley point from Serena Williams puts her within a game of the opening set.
*Williams 4-3 Collins
Five aces already for Serena Williams and while Danielle Collins is battling and competing, she's struggling to make an impact against serve.
Russell Fuller
BBC tennis correspondent at Roland Garros
Williams has found the corner of the court and she does have the break. She had been threatening it - and now she has it.
*Williams 4-3 Collins
What a point that was.
Danielle Collins saved two break points earlier in the set but not this time.
A fantastic rally featuring baseline bombs and drop shots ends with Serena Williams improvising at the net to direct a volley just inside the tramlines.
Williams 3-3 Collins*
Two break points for Serena...
Laura Robson
Former British number one
In this match so far it's 'which American player can get the first huge hit in?' They're both playing so aggressively...
The stats right now are looking really equal.
Williams 3-3 Collins*
Danielle Collins hits a forehand long after an improvised return from Serena Williams.
But she levels up at 15-15 with an exquisite lob that lands just inside the back of the court.
*Williams 3-3 Collins
Serena Williams puts down three real service bombs that Danielle Collins either can't return or can't return very well.
A dominant service game from the 23-time Grand Slam champ.
Russell Fuller
BBC tennis correspondent on BBC Radio 5 Live Sports Extra
Williams has said she feels she is getting a lot of bad bounces.
Isn't that just 'welcome to the world of clay'?
Williams 2-3 Collins*
A service game to love from Danielle Collins.
That will be a relief after being taken to deuce in her opening two service games.
Medvedev 6-4 Opelka
The man mountain that is Reilly Opelka - almost seven foot tall of him - is just not quite at the races at the moment and the new king of clay Daniil Medvedev takes a one set lead over on Court Suzanne-Lenglen.
Let's take in a bit of news from the men's draw...
*Williams 2-2 Collins
Danielle Collins had that aforementioned surgery only eight weeks ago.
And here she is in the last 32 of a Grand Slam. Unbelievable.
She's unable to make much of an impact on Serena Williams' next service game, though, and we're level again.
Russell Fuller
BBC tennis correspondent on BBC Radio 5 Live Sports Extra
The game is Collins', the comeback is complete from this woman who had surgery for endometriosis in April.