Postpublished at 19:16 British Summer Time 28 June 2022
Williams v Tan
Big sister Venus is sat alongside mum Oracene in Serena's support box.
In fact, speaking of Venus...
Harmony Tan beats Serena Williams 7-5 1-6 7-6 (10-7) in tie-break decider
Rafael Nadal defeats Francisco Cerundolo 6-4 6-3 3-6 6-4
Britain's Liam Broady wins 4-6 6-3 7-5 6-7 (2-7) 6-3 against Lukas Klein
Alastair Gray, Jack Draper and Ryan Peniston through; Dan Evans out and Paul Jubb loses in five sets to Nick Kyrgios
GB's Katie Boulter beats Clara Burel 7-5 6-3; Heather Watson also into round two; Swan, Clarke & Kartal out
Women's number one seed Iga Swiatek beats Jana Fett 6-0 6-3
Alex Bysouth, Matt Gault and Ros Satar
Williams v Tan
Big sister Venus is sat alongside mum Oracene in Serena's support box.
In fact, speaking of Venus...
Williams v Tan
France's Harmony Tan's best result at a Grand Slam was reaching the second round at Roland Garros last year and this year's Australian Open.
She saved a match point against 15th seed Elina Svitolina in Melbourne before her comeback was halted by a leg injury and she was taken off court in a wheelchair.
Her biggest win this year was in Guadalajara, where she beat second seed Madison Keys in three sets.
Williams v Tan
Serena Williams is a seven-time singles champion at Wimbledon, winning the last of her titles at the All England Club in 2016.
She has reached the final twice since her return from maternity leave, but lost to Angelique Kerber and Simona Halep in straight sets in 2018 and 2019 respectively.
Broady 4-6 6-3 7-5 Klein
Britain's Liam Broady was a set down, now he's 2-1 ahead, taking the third set 7-5 against Slovakia's Lukas Klein.
Williams v Tan
Sonia Oxley
BBC Sport at Wimbledon
It is not just fans who are getting excited about the return of Serena Williams to Centre Court today.
Fifth seed Maria Sakkari can't wait to see the American great: "I think it's great that we have her back. It's great for women's tennis. Serena is Serena.
"For me she's the best female athlete - not tennis player - athlete in the Open Era. What she has achieved is enormous. I have a lot of respect for her. She's a great role model for all of us. She's just very special and unique. So I'm looking forward to see her playing again."
Williams v Tan
There's huge cheers for Serena as she comes out to warm up.
The coin toss has gone her way and she'll serve to start the match very shortly.
Williams v Tan
A year ago, Serena Williams left Centre Court in tears after slipping and injuring her ankle in her first-round match.
This will be the American great's first singles match since then, after the 23-time Grand Slam champion took an extended break from the Tour.
She made her return at Eastbourne last week, partnering Ons Jabeur in the women's doubles and reaching the semi-finals, before they withdrew following an injury to Jabeur.
Williams v Tan
She's back.
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Nadal 6-4 6-3 3-6 6-4 Cerundolo
BBC Sport
Let's hear from Rafael Nadal, talking after his victory: "First of all all the credit to Francisco, I think he started to play great and was a very tough opponent.
"Three years without being here on this amazing surface, it is amazing to be back and I can't thank [people] enough for the support.
"It is not a surface that we play very often especially in my case in the last three years I didn't put any foot on the grass. Every day is a test and I am at the beginning of the tournament and the difficult circumstances [under which] I arrived here.
"When you play well in Roland Garros it's not much time between. I used to remember all beautiful days I finished the final in Roland Garros and was playing on the grass at Queens but by body is not allowing me."
For me the most important thing is that I am in Wimbledon 2022 and I won the first match."
*Evans 1-6 2-4 Kubler
Harry Poole
BBC Sport at Wimbledon
Not quite the packed house on court two for British number two Dan Evans, who has a sizeable task on his hands against Jason Kubler.
The Australian world number 99 leads by a set and a break, having just consolidated his latest breakthrough for a 4-2 advantage in the second set.
Work to be done.
Nadal 6-4 6-3 3-6 6-4 Cerundolo
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Nadal 6-4 6-3 3-6 6-4 Cerundolo
Zip top on, new cap, Rafa's ready for his post-match duties. Just the small matter of Serena Williams up next...
Nadal 6-4 6-3 3-6 6-4 Cerundolo
Three hours and 33 minutes - probably longer than Rafa Nadal was expecting to spend on Centre Court today. He's finished just in time for The One Show.
Nadal 6-4 6-3 3-6 6-4 Cerundolo
And there it is!
Rafael Nadal has been made to work for it by Francisco Cerundolo, but as the Argentine cups a forehand into the tramlines, it's game, set and match for the second seed. What a contest!
Nadal 6-4 6-3 3-6 5-4 Cerundolo*
Big, big forehand from Rafael Nadal and Francisco Cerundolo can only punch it long in response.
Nadal's return off the next clips the tape and dies at the Argentine's feet. It's match point.
Auger-Aliassime 7-6 (7-5) 4-6 6-6 Cressy
We are into a tie-break, for the second time in three sets, in the match between Felix Auger-Aliassime and Maxime Cressy. They've already been playing for two hours 48 minutes and are still only in the third set.
Nadal 6-4 6-3 3-6 5-4 Cerundolo*
Nadal digs it out with a scrambling forehand and Cerundolo can only coax an effort of his own well wide. It's a good hustle from the Argentine though as he creeps into the net to make it 30-15.
Nadal 6-4 6-3 3-6 5-4 Cerundolo*
Rafael Nadal sprints to the baseline to receive serve. The pressure is on Francisco Cerundolo to serve to stay in the championships now.
Gray 6-3 6-3 7-6 (7-3) Tseng
Alastair Gray is the latest Briton into the second round, having just finished off Tseng Chun-hsin in a third-set tie-break.
Nadal 6-4 6-3 3-6 5-4 Cerundolo*
John Inverdale
BBC Sport at Wimbledon
Nadal is like a steam train now. Three games in a row, and he has Cerundolo on the ropes.
He somehow has to regroup and rediscover what he had for the past hour and a half.