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Jonathan Jurejko
BBC Sport in Melbourne

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Carlos Alcaraz was knocked out of the Australian Open as Alexander Zverev held off a spirited comeback by the Spaniard to win an absorbing quarter-final at 01:20 local time.

Germany's Zverev was rewarded for a rapid start to win 6-1 6-3 6-7 (2-7) 6-4 against Spanish second seed Alcaraz.

Zverev served for victory at 5-3 in the third set but Alcaraz burst into life.

However, the sixth seed made no mistake the second time around to set up a semi-final with Daniil Medvedev.

Earlier, third seed Medvedev won 7-6 (7-4) 2-6 6-3 5-7 6-4 against Poland's ninth seed Hubert Hurkacz.

"I feel a bit destroyed right now," said Medvedev, who clinched victory in just under four hours.

"He played good, I won't be tough on myself. I just had to try and do whatever I could. If I lose, I lose, it's OK."

The 27-year-old Russian is aiming for a second Grand Slam title after winning the 2021 US Open, while Zverev is searching for a first major triumph.

The pair will meet when the men's semi-finals take place on Friday, with defending champion Novak Djokovic facing Italian fourth seed Jannik Sinner.

The two women's singles semi-finals will take place in the second session tomorrow.

• Coco Gauff (US, 4) v Aryna Sabalenka (Blr, 2) - from 08:30 GMT
• Dayana Yastremska (Ukr) v Zheng Qinwen (Chn, 12)

Tigerblade14: Zverev demonstrated courage

nathDegreat: What is happening to Alcaraz? He’s not been himself in the last two Grand Slams

Sam: A brave effort from Carlos but he left himself to much to do. Zverev was on fire for first two sets, big win for him, big test versus medvedev awaits

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Dayana Yastremska says it is her "mission" to show pride in her home country of Ukraine after becoming the first qualifier since 1978 to reach the Australian Open semi-finals.

Yastremska breezed past Czech teenager Linda Noskova 6-3 6-4 in just 78 minutes and will face China's Zheng Qinwen for a place in Saturday's final.

She wrote a message of support for Ukrainian fighters on the camera lens, amid the ongoing Russian invasion.

"I'm very proud of them," she said.

Both Zheng and Yastremska will be appearing in their first major semi-final, with Zheng having previously reached the US Open quarter-finals last year.

The 12th seed fought back to beat Russia's Anna Kalinskaya 6-7 (4-7) 6-3 6-1 in the night session on Rod Laver Arena.

Yastremska is the second qualifier in the Open era to reach the Melbourne Park last four after Christine Dorey in the 1978 tournament.

She dedicated her win to her country, saying: "I think it's my mission here. I'm just trying to give the signal to Ukraine that I'm really proud of it."

"They really deserve huge respect. I always try to write something for Ukraine, about Ukraine."

Mark Woodforde
17-time Grand Slam doubles champion on BBC Radio 5 Sports Extra and BBC Sounds

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That was some of the best tennis that Alexander Zverev has played over five sets. He was white hot and better than that what everyone else left in the tournament has put out so far.

We know he can play like that but we only see a set of it and then it's like he disappears or something causes him to become distracted and he deviates off. That was one of the most complete matches that I've seen him play and he's got to be able to do that two more times.

John: One of the best matches I’ve ever seen. Well done Zverev!

Akhtar: Oh It took a phenomenal performance to knock Alcaraz out

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Britain's Alfie Hewett and Gordon Reid progressed with wins in the men's wheelchair singles and doubles at the Australian Open on Wednesday.

Singles top seed Hewett beat Chile's Alexander Cataldo 6-0 6-2 in the quarter-finals, while fourth seed Reid beat Dutchman Tom Egberink 7-5 6-2.

The Britons, who could meet in the singles final, later teamed up to reach the doubles semi-finals in Melbourne.

Meanwhile, Andy Lapthorne advanced in the quad doubles but lost in singles.

He was beaten 6-1 6-0 in the singles quarter-finals by Dutch second seed Sam Schroder but won 6-0 6-1 alongside American David Wagner against Turkey's Ali Ataman and Brazil's Ymanitu Silva to reach the doubles semi-finals.

There were also defeats for compatriots Lucy Shuker in the women's wheelchair doubles and Gregory Slade in the quad doubles.

Eight-time Grand Slam singles champion Hewett, who won his only Australian Open title last year, was happy to wrap up his singles quarter-final win in 51 minutes with temperatures reaching 29C.

"It was a good match on my behalf, especially with today's hot conditions. You want to spend as little time on court as possible," said 26-year-old Hewett, who will face Belgium's Joachim Gerard next.

Former Australian Open champion Reid, 32, will face 17-year-old Japanese second seed Tokito Oda in the semi-finals.

Mark Woodforde
17-time Grand Slam doubles champion on BBC Radio 5 Sports Extra and BBC Sounds

I did the same injury as Alexander Zverev. I was out for six months way back when I was playing. Even though I got back within the six month period, in the first tournament I was super excited to be back and did well, but then the next four months I was really struggling.

The fact that you have to pay attention to the ongoing rehab and players are asking about you. It's certainly a burden to go into the training room and get treatment and you lose your confidence.

He had to learn how to move on the court and then you have to go through the rebuilding process with your confidence. It takes a long time.

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More from Zverev.

On coming back from a long time out with injury: "It was a very difficult moment obviously in my career and in my life generally because even if I would've lost that [semi-final] match against Rafael Nadal at the French Open, he's won it 14 billion times, a lot of players have lost to him there.

"Having in the back of my mind that I needed to win one match in the next three months to become world number one, that was the most painful part for me and I had to start over. I had to start from zero. I'm happy to be back in the top 10. I'm happy to be back in major semi-finals and hopefully playing for titles again."

On playing Medvedev in the semi-finals: "Maybe this will be it, this will be the place. I'm counting on all of your guys support. I love playing in Australia. We as players, we always say that New York is the most energetic Slam and the loudest and the craziest but for me the crowd is best in Australia because in my opinion the energy and the noise is just as loud but I feel like the Australian crowd has real tennis knowledge.

"They are the most respectable crowd. It's just the nicest to play in. They know when to be loud and know when to be quiet. I enjoy playing here. I know I'm talking too much. I'm sorry, I'm excited."

Some quotes now from Alexander Zverev.

On winning after serving for the match in the third set: "I'm playing one of the best players in the world especially over the last two years. He's been number one and number two in the world and won two Grand Slams.

"When you're up 6-1 6-3 5-2, you start thinking. I mean we're all human. It's a huge honour to play against guys like him and then when you're so close to winning, obviously your brain starts going and it's not always helpful but I'm happy that I got it in the end.

"I fought back quite well in the fourth set, didn't let go and very happy to finish the match."

On how he's feeling after a lot of time on court: "Well I have a lot of blood under my toenails so that's quite painful. I take them out every single match but then obviously when you're playing and running a lot, they came back.

"You know what, I would much rather feel the way I'm feeling right now with maybe a bit of pain here and there and be in the semi-finals, rather than be at home right now and watching the tournament.

"That's why I'm saying I'm fine. I'm happy to be here and ready to get going."

Image source, Getty Images

Britain's Neal Skupski and American Desirae Krawczyk beat Australian duo Olivia Gadecki and Marc Polmans to reach the final of the mixed doubles at the Australian Open for the first time.

Skupski and Krawczyk won 6-4 6-1 on Margaret Court Arena in Melbourne.

They are aiming for their third Grand Slam title together after twice winning the mixed doubles at Wimbledon.

In Friday's final they will meet the pairing of Taiwanese Hsieh Su-wei and Poland's Jan Zielinski.

Gadecki and Polmans broke Krawczyk's serve in the third game of the match, but second seeds Skupski and Krawczyk fought back from 4-2 down and won four successive games to take the opening set.

The second set was more one sided with breaks of serve in the fourth and sixth games.

Hsieh and Zielinski, the third seeds, defeated the Australian team of Jaimee Fourlis and Andrew Harris 7-6 (10-8) 6-2.

Image source, Getty Images

India's Rohan Bopanna will become the oldest tennis world number one aged 43 after he and Matthew Ebden reached the Australian Open doubles semi-finals.

Bopanna and Australian Ebden beat Argentine pair Maximo Gonzalez and Andres Molteni 6-4 7-6 (7-5).

It is the first time Bopanna has reached the top of the world rankings.

"People all over the world, you know, being 40 and above, I think it's just going to inspire them in a different way," he said.

Bopanna and Ebden will face Tomas Machac and Zhang Zhizhen in the last four in Melbourne.

Bopanna became the oldest ATP Masters 1,000 champion when he and Ebden won the Indian Wells doubles title in March last season.

He turned professional in 2003 and has won one Grand Slam mixed doubles title alongside Canada's Gabriela Dabrowski at the 2017 French Open.

Alexander Zverev has won seven times and lost 11 against Daniil Medvedev. No player has beaten Zverev more times in ATP Tour matches than Medvedev.

Alexander Zverev has registered his first top-five win in a Grand Slam, he was 0-10 before this match.

He has reached his seventh men’s singles semi-final at a Slam, moving past Michael Stich; Zverev only trails Boris Becker (18) for the most among German players in the Open Era.

Zverev is the third German to make the semi-finals of the Australian Open on multiple occasions after Tommy Haas (three) and Boris Becker (two) during the Open Era.

Mark Woodforde
17-time Grand Slam doubles champion on BBC Radio 5 Sports Extra and BBC Sounds

It's pretty special. I'm struggling to think of such a high standard, high calibre level of play that I've seen Alexander Zverev play against this standard, against Carlos Alcaraz, the number two player on the planet.

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A huge scream of celebration and relief from Alexander Zverev as he clinched the winning point.

Match point Zverev for the first time today.

Alcaraz drags Zverev into the net with a drop shot, somehow after more than three hours of tennis, Zverev has enough in the legs to get there only for Alcaraz to sweep away a winner, 30-30.