Davante Adams scores hat-trick for Rams
Six games kicking off at 18:00 BST including Chiefs & Eagles
Packers, Broncos & Cowboys in action from 21:00 BST
Listen Live to Colts @ Chargers on BBC Radio 5 Sports Extra from 21:00 BST
Philadelphia Eagles 14–3 Minnesota Vikings
Giant catch from Justin Jefferson in Minnesota as he snags Carson Wentz's 40-yard pass.
Head coach Kevin O'Connell probably just relieved to see the ball in the hands of someone in a purple jersey after those two interceptions.
New Orleans Saints 0-13 Chicago Bears
One-way traffic in Chicago as the Bears increase their lead thanks to an 11-yard touchdown run from D'Andre Swift.
That all came from a short field handed to the Bears by a Spencer Rattler interception just inside opposition territory. Not much going right for the Saints so far.
New England Patriots 10-10 Tennessee Titans
Image source, Getty ImagesAll square in Tennessee after a short pass from Drake Maye finds tight end Austin Hooper in the end zone.
Maye is playing VERY well at the moment - five for five for 51 yards on that play and he also used his legs.
Carolina Panthers 3-3 New York Jets
Tyrod Taylor comes in for Justin Fields at quarterback and his first drive results in a 34-yard Nick Folk field goal.
Carolina Panthers 3-0 New York Jets
In what has been a quiet game so far, a scuffle broke out following a hard tackle to Justin Fields.
After visiting the medical tent as a precaution, he is now back out and sitting on the bench.
Philadelphia Eagles 14–3 Minnesota Vikings
Last time we saw Carson Wentz, he was gifting a touchdown to the Eagles.
Now, he's launched a lost cause into the heart of the Philadelphia defence and has been picked off again.
Vikings in trouble at the moment.
Miami Dolphins 3-10 Cleveland Browns
Image source, Getty ImagesA rare moment of real quality in Cleveland as Quinshon Judkins breaks away for a huge 46-yard touchdown run.
That's a third rushing touchdown of the season for the rookie running back, who has been one of the few plus points for a struggling Browns offence.
Las Vegas Raiders 0–14 Kansas City Chiefs
Too easy.
Patrick Mahomes fires an eight-yard pass into Hollywood Brown who escapes coverage to score.
Chiefs offence is motoring.
New Orleans Saints 0-6 Chicago Bears
The Bears double their advantage with Jake Moody slotting a second field goal of the game - this time from 39 yards out to make it 6-0.
It's not been great so far from either quarterback - Caleb Williams has thrown a pick but has got away with it, while Spencer Rattler has completed just two passes for a total of six yards.
Philadelphia Eagles 13–3 Minnesota Vikings
That'll sting for Vikings quarterback Carson Wentz.
Against his former team, he's just slung his pass straight into the grasp of Jalyx Hunt, who has the freedom of Minnesota to run into the end zone for the Eagles.
Out of nowhere, Philadelphia stretch their lead.
Las Vegas Raiders 0–7 Kansas City Chiefs
Downfield shot from Patrick Mahomes is so close to connecting with receiver Tyquan Thornton.
Brilliant stop from Darnay Holmes denies him a free run at the end zone.
Miami Dolphins 3-3 Cleveland Browns
The Dolphins level the scores thanks to Riley Patterson's 33-yard field goal, on a drive built on De'Von Achane breaking off for a speedy 46-yard run.
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(18:00 BST unless stated)
Most of the early games are at the end of the first quarter so here are the latest scores.
Las Vegas Raiders 0–7 Kansas City Chiefs
Two more catches for Rashee Rice on this second Chiefs drive.
He's definitely back in business.
Kansas City threatening another score here as the first quarter nears an end.
Miami Dolphins 0-3 Cleveland Browns
The Browns generate just enough offence, albeit with a big penalty in there, to get close enough for Andre Szmyt to drill a 30-yard field goal to go ahead.
It's tough going in this one though.
New England Patriots 3-10 Tennessee Titans
Cam Ward sends a 38-yard pass to a running Chimere Dike at deep left, who gets his first NFL touchdown.
Joey Slye converts the extra point.
Will the Pats answer back again?
Carolina Panthers 3-0 New York Jets
Nearly at the end of the first quarter and barely 60 yards of passing combined between these two quarterbacks.
Ryan Fitzgerald's 30-yard field goal puts Carolina on the board first.
Miami Dolphins 0-0 Cleveland Browns
Almost a quarter gone and the two QBs in this game, Dillon Gabriel and Tua Tagovailoa have combined for four completed and 30 yards.
Sums the game up so far...
Philadelphia Eagles 7–3 Minnesota Vikings
Shocker for Minnesota Vikings as they lose 32 yards from a busted snap on third down.
Quarterback Carson Wentz manages to scramble back and retrieve it but they'll have to settle for a field goal.
Duly buried from 59 yards by Will Reichard.