Manchester United will feel they should be ahead after two very presentable chances in a short space of time. The hosts have gone a bit quiet, as have their fans. Can Louis van Gaal's side find a goal in the final third? 

Unlucky! Jesse Lingard arrives on a cross from the left from Ander Herrera, he smashes a volley back from whence it came and he's really unfortunate to see his strike smash the crossbar...

Chances at both ends! First, goalscorer Pione Sisto shoots from 20 yards but it's a routine catch for Sergio Romero in the United goal. Then the men in black counter-attack, Daley Blind whips over a fantastic ball and Juan Mata gets his angles wrong, heading wide from about 10 yards!

Perhaps the cross was a touch high in fact. Blind has arguably been United's best attacking outlet tonight. 

Yousef: Have a feeling I'll be telling my kids about how good United were back in the day, like my dad telling me about his Leeds...

Image source, Rex Features

A brighter, better start for Manchester United to this second half as Memphis Depay spins out of trouble on the left wing, cuts inside but then loses out as he is crowded out. If Louis van Gaal wants to change things from the bench he hasn't got much in the way of experienced, attacking options. Throw Will Keane on?

Memphis Depay is caught offside as he looks for an early surge down the middle. There's a lot of talent in that boy, somewhere. He just hasn't looked settled at all since joining Manchester United, bar that one good game in Europe.

Anthony Martial again just walks past defenders and tees up Jesse Lingard, but he leans back, gets his form all wrong and skies a shot over the top. 

DSBrooks: United are a desperate side, utterly rudderless, drifting aimlessly downstream. Van Gaal with notepad, clueless at the helm.

Anthony Kariuki: Limp. Lame. Lifeless.

Francis Edwards: Am I the only one who remembers what watching Chelsea under Mourinho was like? Don't United fans wanted entertainment?

A nice bit of the Alan Parsons Project, think Chicago Bulls, greets the players back out of the tunnel and we are away...

It's pretty tight and cagey in the early kick-offs across the continent - no team has more than a one-goal lead. In fact Tottenham, with their away goal, look the best placed.

See all of the scores here. 

Now that is a banner! Imagine getting that on the train...

Anthony Crolla won't be happy in that away end after the first half ends with the scores level. Manchester United have at least got an away goal on the board though.

These sides meet again in the second leg at Old Trafford next Thursday...

Image source, Reuters

David: Anything but a win tonight and surely van gaal has to go. He's not only affecting our results but embarrassing us too.

JonDaniel Harris: Am I the only United fan worried about Shrewsbury? We are awful.

Sushant Shetty: Agree #mufc, external are having a terrible season but look at that injured Xl & we cud challenge for the title. Any team would struggle

Zero added time added as the whistle goes. The Herning Arena is bouncing now...

James Foster: Midtjylland tear us to shreds and then Depay scores against the run of play. Well who'd be a Man Utd fan...

Sanj: This makes a nice to change to the usual #UEL, external Knockout Rounds. Hopefully a sign to come that our sides will take it seriously

Spurs have a crucial away goal in the night's other game as Nacer Chadli steers home from the penalty spot.

Follow that game here. 

Vaclav Kadlec will be having nightmares about that miss for the rest of his days. He even had a team-mate alongside for the tap in but he bottled his shot. Extraordinary. 

YOU HAVE TO SCORE! My word!

How did that even happen? One clearance is enough for Midtjylland to have two players clean through from the halfway line! They have to score but Vaclav Kadlec almost has too much time and ends up shooting at Sergio Romero.

WHAT A CHANCE!