Off we go in the two early games at the Emirates and St Mary's. Big one down in Southampton.

HUGE game for both sides at the bottom. All set?

Yousuf: I'm not too sure about Caballero but if tonight goes wrong, I won't blame Sarri. No player is bigger than the team.

Lifa: Again Sarri gets his team selection wrong. Yes Kepa deserves to be dropped but RLC and CHO have to start. The coach keeps convincing us he's not good enough to make bold decisions.

Out they come! Andrew Surman looked like he was in a different world in the tunnel. Full on game face.

What can Bournemouth do tonight?

Image source, Reuters

Ryan Brennan: Hoping Chelsea play as well as they did against city!! Glad to see Zappacosta can't be used as a sub also. Happy to see Emma and Tom keeping us updated as well! Also hoping for a Higuain hatrick because I really need some bonus points in my fantasy team.

Loving this positivity from Ryan! Fingers crossed for your fantasy team.

Watford

Watford head coach Javi Gracia on the threat posed by Mohamed Salah: "I remember in the last game we played against him he scored a lot of goals.

"I try to learn from all the games, of course... we have analysed the last games against them, this season and last season as well, and we try to do better next time."

Image source, Getty Images

Chris Bevan
BBC Sport at Etihad Stadium

Image source, Getty Images

I don’t think Manuel Pellegrini experienced much t-shirt weather in February during the three years he spent in Manchester as City manager between 2013 and 2016, but he must have been enjoying the sunshine here earlier ahead of his first return to the Etihad since Pep Guardiola replaced him.

It’s a bit chillier here now the sun has gone down but Pellegrini, who won three trophies during his time with the Blues and was dubbed ’This Charming Man' by supporters, is guaranteed a warm reception later.

The feeling is mutual, judging from the comments Pellegrini made before the Hammers held Liverpool at the start of February, when he admitted he was still a City fan and was happy to do them a favour in the title race.

That thinking doesn’t apply tonight, obviously. Another City title-winner, Samir Nasri, starts for West Ham and will also be hoping to put one over his former side, while Blues cult-hero Pablo Zabaleta is on the bench.

I don't even know how that really works but WHAT a family tree!

Mark Scott
Match of the Day commentator

Manchester United's injury crisis has improved Palace's chances of finally winning a Premier League game against them.

Their big victory at Leicester last time out not only eased the Eagles' relegation worries, it also saw them produce the kind of efficiency in front of goal that they've been sorely lacking this season.

With his offensive options severely depleted, Ole Gunnar Solskjaer has called on Alexis Sanchez and Romelu Lukaku to "step up and play to their potential".

Opportunity could also knock for the likes of Angel Gomes, James Garner and Tahith Chong, with Solskjaer stating the teenage trio "are ready" if required.

Image source, Reuters

Chelsea

Image source, Getty Images

Chelsea manager Maurizio Sarri speaking to BT Sport: "I think we did a good performance in the final so we are disappointed only about the result. In this match it is only important the result."

On dropping goalkeeper Kepa Arrizabalaga to the bench: "It's a choice. It's a message to my group.

"That we are a group and not 25 players. It's my choice."

On Willy Caballero: "I think he is ready, he has good experience. We are not worried with him."

Liverpool

Liverpool manager Jurgen Klopp on the title run-in: "We don't have to look as far ahead as 11 games.

"It is so positive. If you only judge the moment and see the opportunity everything is fine.

"If you look back then it makes life more uncomfortable.

"In a situation where you can be champions for the first time in your life it is a pure opportunity and you have to use that on the front foot."

Image source, BBC Sport

Just under 15 minutes to go until kick-off. The Emirates still has plenty of empty seats but it's starting to fill. The Arsenal players head down the tunnel but Bournemouth are still finishing up their warm-ups.

Image source, gett

Simon Stone
BBC Sport at the Etihad Stadium

West Ham are giving a debut tonight to a 19-year-old defender who shares the same name as a disgraced Olympic sprinter.

West Ham's Ben Johnson has been with the club since he was seven and has made rapid progress since he moved back from being a winger.

Defensively, he is going to have his hands full obviously.

But Johnson has exceptional pace and could pose a problem or two himself if he gets the chance.

Colin: Origi is good for a couple of goals per season. Fingers crossed today’s the day.

Jon: Think that United will struggle with that weakened team. Deffo Crystal Palace's for the taking!!

Crystal Palace

Crystal Palace manager Roy Hodgson: "I'm looking forward to it. I was disappointed to lose the game last year.

"I'm expecting this one to be a good game of football too. It's going to be a tough ask for us. They're in good form."

Sho: Will be interesting to see how United line up. I think Dalot will be at right back with Young in front to protect against Zaha.

Briyan: Dropping Kepa is the right call although in a game of this magnitude you need a strong team. The need to send a message to your players outweighs that though. Big call, Good call.

Liverpool are top of the table and have an excellent record against tonight's opponents. Watford's two most recent trips ended in a 6-1 defeat in November 2016 and a 5-0 loss in March 2018.

They have lost 10 of their 11 league games away at Anfield and Liverpool have not lost a game at home since April 2017 - that's 34 matches in total.

But Watford come into the match in good form having lost only one of their past 11 matches in all competitions.

And there's some concern over Liverpool's form after they dropped nine points in their last seven league games. They only dropped six in their first 20 games.

Jurgen Klopp's side have also registered just three shots on target in their previous two matches, failing to score in either.

Their opponents were Bayern Munich and Manchester United though, so it's hardly anything to get too worried about just yet.

Image source, Getty Images

Phil McNulty
BBC Sport chief football writer at Stamford Bridge

Maurizio Sarri will have plenty of supporters for his decision to drop Kepa Arrizabalaga - he undermined the manager's authority and credibility with his one-man rebellion on Sunday and has been punished.

Sarri will also know much hinges on his big change. He needs Willy Caballero to perform and Chelsea to get a good result as the consequences could be huge for the Italian if it goes wrong.

Image source, Getty Images

Arsenal

Arsenal head coach Unai Emery on the club being linked with Roma director of football Monchi: "I was usually working with a sporting director in all of the teams.

"The club is working on how we can improve, how we can be better in the present and the future with the people working for us."

BBC Four

As well as tonight's Premier League action, England women are kick-starting their SheBelieves Cup campaign.

They take on Brazil and you can watch the game live on BBC Four and online from 20:45 GMT. Caroline Chapman is also doing live text commentary if you can't get to a TV.