Portuguese midfielder Bruno Jordao, 20, makes his Wolves debut while 22-year-old defender Max Kilman, who played against Pyunik in a Europa League qualifier, starts for Nuno Espirito Santos' side.

Wolves XI: Ruddy, Vallejo, Bennett, Kilman, Doherty, Jordao, Gibbs-White, Neves, Neto, Cutrone

French forward Yakou Meite, 23, captains Reading while there's a return to the starting XI for American defender Matt Miazga.

Former Manchester United defender Tyler Blackett and ex-Liverpool and Stoke midfielder Charlie Adam also start.

Reading XI: Virginia, Miazga, Rinomhota, McIntyre, Boye, Meite, Howe, Blackett, Adam, Richards, Barrett

Simon Stone
BBC Sport at Old Trafford

That is some statement by Ole Gunnar Solskjaer.

Axel Tuanzebe is 21 years of age and is starting his seventh game for Manchester United.

Norman Whiteside captained United when he was 20 - but he had played in the World Cup for Northern Ireland by then.

I will be interesting to see if Tuanzebe starts ordering Paul Pogba around.

Paul Pogba is back in the Manchester United line-up after almost a month out with an ankle injury.

Axel Tuanzebe captains the side against his hometown club. Only Aaron Wan-Bissaka and Andreas Pereira stay in from the 2-0 defeat by West Ham.

Man Utd: Romero, Wan Bissaka, Tuanzebe, Jones, Rojo, Fred, Pogba, Andreas Pereira, Lingard, Chong, Greenwood. Subs: Lindelof, Mata, Grant, James, Garner, McTominay, Williams.

Two changes for Rochdale as Jimmy Keohane and Aaron Morley replace the injured Eoghan O'Connell and Rekeil Pyke.

Rochdale: Sanchez, Matheson, Morley, McNulty, Norrington-Davies, Dooley, Williams, Rathbone, Camps, Keohane, Henderson. Subs: Andrew, Lynch, Wilbraham, Ryan, Bradley, Tavares, Thomas.

Image source, Getty Images

Thoughts on team selection? Bothered about winning the cup at all? Fancy your side for a big upset?

Let us know...

Only Callum Robinson keeps his place in the Sheffield United team from their win over Everton. Ravel Morrison, Lys Mousset and Phil Jagielka are among the 10 changes.

Sheff Utd: Moore, Jagielka, Stearman, Bryan, Kieron Freeman, Luke Freeman, Besic, Morrison, Osborn, Robinson, Mousset. Subs: Stevens, Fleck, Basham, McBurnie, Norwood, Verrips, Clarke.

Sunderland hand debuts to summer signings Joel Lynch and Laurens de Bock in defence. In total there are eight changes from the weekend. Aiden McGeady misses out through injury.

Sunderland: Burge, Conor McLaughlin, Flanagan, Lynch, De Bock, McGeouch, Power, Maguire, O'Nien, Embleton, Wyke. Subs: Dobson, Grigg, Leadbitter, Hume, Patterson, Taylor, Connelly.

Midfielders Scott Fraser and John-Joe O'Toole and defender Reece Hutchinson come in for Burton. New/old signing Lloyd Dyer is on the bench.

Burton XI: O'Hara, Edwards, Wallace, Fraser, Broadhead, Akins, Hutchinson, Sarkic, Nartey, O'Toole, Boyce.

Bournemouth make 10 changes for the trip to Burton, with Dominic Solanke the only player to keep his place from the win at Southampton last Friday.

Ryan Fraser gets a start, Lewis Cook continues his step up to full fitness and 19-year-old Gavin Kilkenny comes into midfield. Lloyd Kelly makes his competitive debut.

If they need them, the Wilsons (Callum and Harry) are on the bench.

Bournemouth XI: Travers, Francis, Mepham, Simpson, Kelly, Cook, Surman, Kilkenny, Ibe, Fraser, Solanke.

Actually, don't answer that.

ELEVEN changes for Liverpool from the side that started the 2-1 win over Chelsea last weekend. The likes of Sadio Mane, Roberto Firmino and Mohamed Salah are given the night off as Jurgen Klopp names a mixture of youth and experience.

Irish keeper Caoimhin Kelleher, 20, makes his senior debut while 16-year-old Harvey Elliott, 17-year-old Dutch defender Ki-Jana Hoever, 18-year-old midfielder Curtis Jones and 19-year-old forward Rhian Brewster also start.

Liverpool XI: Kelleher, Hoever, Gomez, Lovren, Milner, Oxlade-Chamberlain, Lallana, KeIta, Elliott, Brewster, Jones.

MK Dons have make six changes to the side that started the 1-0 defeat at home to Sunderland.

Keeper Stuart Moore, George Williams, Regan Poole, Alex Gilbey, Jordan Bowery and Brennan Dickenson all return.

MK Dons XI: Moore, Williams, Walsh, Poole, Gilbey, Bowery, Dickinson, McGrandles, Brittain, Nombe, Kasumu.

Frank Lampard has named an entirely new Chelsea team to the one that lost 2-1 to league leaders Liverpool on Sunday.

Reece James, 18 and Marc Guehi, 19, make their first team debuts, while Billy Gilmour, 18, is handed his first start.

Chelsea XI: Caballero, James, Guehi, Zouma, Alonso, Gilmour, Barkley, Pulisic, Pedro, Hudson-Odoi, Batshuayi

Grimsby Town have named five defenders in the starting XI so could play a 5-3-2 formation at Stamford Bridge.

Grimsby Town XI: McKeown, Hewitt, Hendrie, Pollock, Davis, Gibson, Hessenthaler, Clifton, Whitehouse, Green, Hanson

Ahead of a game at Chelsea on Saturday, Brighton make 11 changes from the goalless draw with Newcastle.

Brighton XI: Button, Davies, Duffy, Roberts, Bong, Gwargis, Baluta, Jenks, Cochrane, Richards, Connolly.

Image source, .

Nine changes for Aston Villa. Kortney Hause, a summer signing from Wolves, and Ezri Konsa, who joined from Brentford, are among the starters.

Aston Villa XI: Steer, Elmohamady, Konsa, Hause, Targett, McGinn, Luiz, Hourihane, Jota, Davis, Trezeguet.

West Ham hand a first start to midfielder Nathan Holland in one of nine changes from the weekend. Jack Wilshere, Albian Ajeti and Robert Snodgrass are among the other changes.

Tarique Fosu is on the bench for Oxford after his hat-trick in their 6-0 win at Lincoln on Saturday. Former West Ham winger Rob Hall is one of six players to come into the team.

Oxford: Eastwood, Long, Dickie, Moore, Ruffels, Hall, Brannagan, Thorne, Baptiste, Forde, Mackie. Subs: Taylor, Woodburn, Fosu, Stevens, Sykes, Agyei, Jones.

West Ham: Roberto, Zabaleta, Balbuena, Diop, Masuaku, Sanchez, Snodgrass, Wilshere, Fornals, Holland, Ajeti. Subs: Fabianski, Cresswell, Felipe Anderson, Noble, Goncalo Cardoso, Haller, Coventry

Eight more Carabao Cup ties to be played tonight to complete the fourth round line-up:

Brighton v Aston Villa

Burton Albion v Bournemouth

Chelsea v Grimsby Town

Milton Keynes Dons v Liverpool

Oxford United v West Ham United

Sheffield United v Sunderland

Wolves v Reading

Manchester United v Rochdale (20:00)

Image source, Getty Images

Last night Tottenham were kicked out of the Carabao Cup by lowly Colchester in a dramatic night of League Cup action.

Tonight it's the turn of Liverpool, Chelsea and Manchester United to try and avoid a slip-up with much-changed sides.

Are we on for another shock or two, or three?