Moments after Liverpool make that final change Andy Robertson looks to be struggling. Hamstring?

Six minutes left.

Liverpool make their fourth and final change - Roberto Firmino comes off and recent signing Takumi Minamino gets on. Not scored for the club yet...

Helles: The spirit of Loris Karius is alive and well at Anfield.

Stuart: I despair with some fickle supporters (Conor), I'm a Liverpool fan and Adrian still has my support. Players make mistakes, it is what it is.

I can certainly see why you would not be a fan of the way Atletico Madrid play but I would say they have been so successful for so long that you can only tip your hat to them at times.

Roberto Firmino put Liverpool in the driving seat in the 94th minute and within 10 minutes the visitors were heading through...

Unless Divock Origi and co can summon up some magic again.

Two goals needed in 10 minutes.

Since the start of the 2017-18 campaign, Liverpool's goalkeepers have made more errors leading to goals in the Champions League than any other team's keepers in this period and four in total.

One via Adrian and three courtesy of Loris Karius

Guillem Balague
Spanish football journalist on BBC Radio 5 Live

Atletico Madrid came back from the dead. That is what they are made of. We keep being surprised by them, but maybe this shows that we shouldn't be. I would say that this isn't an accurate representation of the full match though.

Nobody in an Atletico Madrid shirt outside of their own penalty area as they clear a Liverpool cross. Massed ranks. VVD just staying up front now.

Paul: Here’s the real point. Liverpool failed to take chances in 90 mins. Don’t make this about Adrian.

Conor: Doesn't matter how well Adrian has played all season. He has just lost all his fans with us. Two awful, awful mistakes in 15 minutes.

It's pretty much a back 10 for the visitors now as Jan Oblak again does brilliantly to claw out a low cross from Sadio Mane...

Pat Nevin
Former Chelsea and Scotland winger on BBC Radio 5 Live

You certainly couldn't have called that - a mad 15 minutes! You have to put it down to goalkeeper error, it gave Atletico that confidence. But - with the players Liverpool have it's not over yet.

Here we go then. Hold on to your hats.

Image source, Getty Images

Fabinho has come on for Jordan Henderson and Divock Origi is on for Gini Wijnaldum.

Tom: Have some supporters only just joined football? The away goal rule has been here for decades.

Andrew: Adrian is doing his best Hugo Lloris impression.

Anfield rouse their players with a chorus of YNWA. Another great European night was promised by pundits and it has delivered for sure.

Liverpool will have 15 minutes to score twice or it's end of break.

Liverpool need TWO more goals now.

Chris: So it's been attack for three minutes, score, defend for three hours, attack for three minutes and score. just imagine if Atletico had attacked for the whole two games?

James Milner drives Liverpool on down the left, Atletico just pack the penalty area with bodies and defend so well.