Image source, BBC Sport

• Everton have lost just one of their last eight Premier League games against Leeds (won four, drawn three).
• Leeds won this fixture 1-0 last season, following a 13-game winless away league run against Everton. They have not won back-to-back league visits to Goodison Park since November 1976.
• Since the start of October, Everton have won fewer points (six) than any other side in the Premier League. The Toffees have won just one of their 15 league games in this run (drawn three, lost 11) and have kept just one clean sheet.
• Leeds have lost all four of their away league games kicking off at 15:00 on a Saturday since their return to the top flight in 2020. The Whites’ last such victory in the competition was at Blackburn Rovers in April 2004 (2-1).

Manchester United

Manchester United defender Raphael Varane, speaking to BT Sport: "We are disappointed about the result, it is not enough for us. We have to keep pushing. In last three or four games we have played much better but the result is not enough for us. We have to fight and be focused on the next game.

"It is the second time the beginning of second half has not been good enough and we concede a goal. We had good opportunities in the first half."

On finishing in the top four: "We never give up and we have to fight until the end."

Southampton

Southampton striker Che Adams speaking to BT Sport: "We've had a great week this week, everything just keeps building and building. Obviously everybody is delighted. Personally, it is nice to be amongst the goals, but more importantly, it is about the points on the board and we've done that with a huge display today."

On his goal: "I was half ready to go for the rebound because I thought it was going to come out, but I just had one thought in mind, to go for the far corner and I'm just glad it came off."

On his work rate in the game: "That is what the gaffer wants and everybody knows we are a pressing team. When we press, not many teams can handle it. When everybody is at it like today, we can beat anyone."

On Southampton's response to going behind: "We managed to dust ourselves down and go into the second half flying. Getting a goal helped us and we grew more into the game."

Leon Osman
Former Everton midfielder

Saturday's home game against Leeds is absolutely huge for Everton's season, and their Premier League survival.

I can't help but be worried about my old club because of their dismal form, which is the worst in the top flight. For months now, it has not taken much to out-fight them and it is too easy to score goals against them.

Whichever way you look at it, they are in a relegation battle and, to get themselves out of this mess, Everton need to find a way of becoming Everton again. By that, I mean playing with confidence and freedom but also showing the tenacity and tough tackling that is in the club's DNA.

Read more from Leon Osman on Everton.

The game at Goodison Park is a bit of a battle of the treatment rooms.

Leeds have struggled with injuries throughout this season and are still without captain Liam Cooper and star players Kalvin Phillips and Patrick Bamford.

Everton lost Yerry Mina and Demarai Gray to injuries at Everton, with the former out for up to 10 weeks. Ben Godfrey is also out until March after tearing a hamstring in the FA Cup fourth-round win over Brentford on Saturday.

On the plus side for the Blues, striker Dominic Calvert-Lewin - an unused substitute in midweek - is again available for selection.

Image source, Getty Images

Everton boss Frank Lampard has insisted that it is about getting results right now as opposed to building a culture within the club.

The Toffees have won just once in the Premier League since September and are 16th in the table, only two points clear of the drop zone.

"I think it is important that the players have confidence in our relationships and confidence in how we are working on the training ground," he said.

"We haven't got loads of time at the minute to talk about culture and value, it needs to just be how we are, how we behave and what we want at the end of it.

"We can talk about culture and values down the line with a long-term vision, because you always want to move forward as a club.

"But the short-term is train well, be together, be strong and try to get results."

Lampard has also acknowledged that a connection with the fans will be key for Everton to turn their fortunes around.

"[The fans] will be hugely important, the fan support, it is their life and their passion," he said.

"The players have to replicate that in their performances, they have to play with energy and if we work together in that sense then we will be so much stronger."

Image source, BBC Sport

Lawro's prediction: 1-0

Everton have got injury problems in the centre of their defence, but they have been struggling at the back for a while now anyway, even when everyone was fit.

I am still going for Frank Lampard's side to win this one, but it won't be easy and the crowd will definitely play a big part in making that happen.

That is a big thing that Everton have as a positive now. The discord you saw in the stands when Rafael Benitez was in the dugout has gone, and of course it makes a massive difference when everyone is together and behind the team.

Jeremy's prediction: 1-3

Find out how Lawro and Jeremy think the rest of the weekend's fixtures will go

Image source, Getty Images

Crystal Palace boss Patrick Vieira says Wilfried Zaha is "happy to wear the shirt", but he has challenged the forward to increase his goal tally.

Zaha scored a wonder goal but also missed a penalty in the 1-1 draw at Norwich City - and there has been speculation about what will happen in the summer, given he is out of contract at the end of next season.

"I said he has to score more because of his ability to do so. A player with his ability can create and score more - but it isn't going to be him by himself," said Vieira.

"What's good for him is to have players around him taking responsibility to take pressure off his shoulders. We have players who can score goals and deliver.

"The positive is having a team performance - it allows him to express himself.

"He's under contract, so that means he is happy to wear the shirt and perform well."

Brentford "need to get some results", according to former Manchester City midfielder Michael Brown, after five Premier League defeats in a row has seen them slip to 14th in the Premier League table.

Thomas Frank's side put in a resilient performance at Etihad Stadium on Wednesday but it was not enough to prevent the runaway leaders cruising to a comfortable win.

"We're looking at a team that are not feeling the pressure because the bottom sides have under-performed in terms of points," Brown said on BBC Radio 5 Live's Football Daily podcast.

"They showed good signs against City, were well-organised and hard to beat, but they didn't have much creativity without Ivan Toney.

"And then they made mistakes - we're now at the business end of the season and they need to pick up some results."

The Bees are six points clear of the bottom three but have played more games than all the sides below them.

Listen to full discussion on Brentford from 19'09 on BBC Sounds

Image source, BBC Sport

• This is Brentford’s first home league game against Crystal Palace since a 2-1 win in September 1963; the Bees have lost just one of their last 10 home league games against the Eagles (W7 D2).
• The reverse fixture between Brentford and Crystal Palace finished 0-0 – only once before have the Eagles had two goalless draws against an opponent in the same Premier League campaign, doing so against Manchester City in 1992-93.
• Crystal Palace have won just two of their past 20 Premier League London derby matches (D9 L9), conceding at least three goals in all nine of their defeats in this run.
• Brentford were unbeaten in their first three Premier League London derbies (W2 D1) but have lost their last two, losing to Chelsea and Spurs. The Bees haven’t lost three in a row against fellow London opposition in the league since a four-game run between November 2011 and September 2012, losing twice to Charlton and twice to Leyton Orient in League One.

Image source, BBC Sport

Lawro's prediction: 2-1

Crystal Palace are still waiting for their first league win of 2022, but I don't think they have anything to worry about.

The Eagles are playing well and should have beaten Norwich on Wednesday for starters. That's been a theme of their season, in that they have not always got the points their performances deserve, but I'd still say Patrick Vieira is doing an excellent job as manager.

Brentford are on an even worse run, and have lost their past five league games.

What I like about the Bees is that there is no suggestion their manager Thomas Frank is under pressure and nor should he be. They are still creating chances and I actually think their losing run ends here.

Jeremy's prediction: 2-2

Find out how Lawro and Jeremy think the rest of the weekend's fixtures will go

Time to start building up to the three 15:00 GMT games with a bit of reaction from Old Trafford sprinkled in.

For only the second time in their Premier League history, Manchester United have failed to win back-to-back matches despite being ahead at half-time in both, having last done so in December 1998.

Nedum Onuoha
Former Manchester City defender on BBC Two

Manchester United don't have a belief in the structure that has been put around them, because if they did they'd always stick with it.

The best teams stick to what they believe and what has got them where they are. For United, they are a one-half team; they were great first half, then it is completely different.

Bhararg Ganapathi: If Harry Maguire continues to play, the entire United board and the owners need to be sacked.

Sho: Broja has ripped Maguire to shreds today.

Roger: I've loved watching Man Utd since the Busby Babes. No more.

It is two points dropped for Manchester United, whose top-four hopes suffer another blow. They receive boos from the fans.

Cheers from the away end, though. Another impressive result for Saints, who have taken four points from trips to Tottenham and Man Utd this week.

Southampton have a goal-kick. Is that it?

Late change for Saints. Oriol Romeu is replaced by Ibrahima Diallo.

A minute remains.