Image source, Getty Images

Italy make three changes from the loss to England, with Braam Steyn, Nicola Quaglio and Luca Bigi all selected.

Haed coach Conor O'Shea has kept faith with fly-halfs Tommaso Allan and Carlo Cann, meaning Dublin-born Ian McKinley misses out of the squad to face his Irish compatriots.

Italy: Minozzi; Benvenuti, Boni, Castello, Bellini; Allan, Violi; Quaglio, Bigi, Ferrari, Zanni, Budd, Negri, Steyn, Parisse (capt).

Replacements: Ghiraldini, Lovotti, Pasquali, Ruzza, Mbanda, Gori, Canna, Hayward.

Image source, Getty Images

Ireland have made four changes to the side that beat France in Paris last weekend.

Leinster back row Jack Conan will make his Six Nations debut in place of British and Irish Lion CJ Stander while Jack McGrath, Devin Toner and Dan Leavy also come into the pack.

Twenty-year-old back Jordan Larmour, who has scored six tries in 14 games since making his Leinster debut, is among the replacements.

The starting backline is unchanged from the dramatic win as last-gasp drop-goal hero Johnny Sexton again starts at fly-half despite earlier speculation that the British & Irish Lions star could be rested for the visit of the Italians.

Ireland: Kearney; Earls, Henshaw, Aki, Stockdale; Sexton, Murray; McGrath, Best (capt), Furlong, Henderson, Toner, O'Mahony, Leavy, Conan.

Replacements: Cronin, Healy, Porter, Roux, Stander, Marmion, Carbery, Larmour.

Let's fly over to Dublin now where Ireland and Italy are coming onto the field.

Here's your team news...

Catherine Spencer
Ex-England rugby union captain on BBC Radio 5 live sports extra

I've been really impressed with Ellie Kildunne today. She has been dangerous throughout and has scored two lovely tries.

Danielle Waterman's experience and skill got the ball to her and then she flew through what seemed like the whole Welsh defence.

Perhaps Simon Middleton is planning to mould her into a future Emily Scarrett - she's shown everything today to suggest she could live up to that.

Job done for England. Not the 63-0 of last year but they gave it a good go.

Ellie Kildunne with an outstanding solo effort at the death in wet and cold conditions at the Stoop.

Two from two for last year's Champions.

And it's onto the next...

Image source, Rex Features

Two minutes to play in the Women's Six Nations and Wales are running it from deep. Not a great decision.

Another handling error as the women in red are closed down by white shirts and England will have the put-in on the halfway line.

Wales are showing character here, but they're up against a far better side. It's been tough.

Poppy Cleall is still driving through defenders after 75 minutes as she smashes into Hannah Jones, before Simon Middleton's side are ushered over the sideline.

If the Romans are making a belated attempt to invade Ireland, they are banking on charm and and cheery demeanour rather than military might.

The bookies don't fancy their chances apparently. They have Ireland by 34 points.

There's been a good turnout at the Stoop on a wet and cold afternoon. England fans will be pleased having seen their side deliver a solid performance against the old enemies Wales, despite the rain.

But over in Dublin, it all looks a bit sunnier. Just have a look at these chaps...

Catherine Spencer
Ex-England rugby union captain on BBC Radio 5 live sports extra

The forward power of England has been unstoppable. They stole the ball three times in a row from a Wales scrum and Poppy Cleall got in for her second try. She is becoming so influential but is just one of so many threats for England.

It's 45-0 and the England coaching set-up, including Simon Middleton, still haven't cracked a smile.

I think they need to see Prince Harry and the unicorns again...

Image source, Rex Features

George Casely: Read many people whinging about uneven playing field and financial superiority etc How is this England Ladies' fault? It's a well established international sport -maybe divert your angst to the other home nations and their funding mechanisms! Come on England!!!

Anon: Anonymous is spot on - unfair for professionals to play amateurs at any sport so this is a bit of a pointless contest.

Don't forget to include your name on texts...

Image source, Rex Features

No. The ball was grounded by Wales, and we come back to the England scrum five metres out.

I can only see one outcome here...

A brief pause for a TMO review, but the ball went forward before the grounding off Rowena Burnfield.

Wales will have a scrum on their five-metre line. Huge pressure for the replacement pack and it's slippy underfoot now too.

They get the ball out, it's taken back in and then knocked on. At the very least England will come back for the scrum... but have they got the ball down?

Oooof. That looks painful. Wales replacement prop Cerys Hale lands awkwardly on her knee and she's helped off the field by the physio.

Catherine Spencer
Ex-England rugby union captain on BBC Radio 5 live sports extra

It's really wet out there now but the players are used to producing good rugby in these conditions. The game has gone a bit scrappy though so I'd like to see the sides start cleaning it up again.

Image source, Rex Features

Wales have struggled to put any pressure on England today. They've got 15 minutes to get on the scoreboard, but are they too tired after an afternoon of defending?

We've got a scrum in the midfield, England's new scrum-half Caity Mattinson puts in and eventually boots a well-placed kick to pin Wales back in the corner.

England showing they have strength in depth and real quality off the bench. Wales just can't compete at the moment, and there's another terrible line-out throw.

Italy's last victory in the Six Nations was 2015's 22-19 victory away to Scotland.

A glorious day and the Azzurri keep travelling, big on passion but light on numbers.

There's 20 minutes left to play here at Twickenham Stoop, and England are ringing the changes. Job done.

Meanwhile in Dublin...