Favourites at Twickenhampublished at 1:30pm
England v Wales (14:00 BST)
Gareth Griffiths
BBC Sport Wales at Twickenham
Not many Wales sides have come to Twickenham as favourites.
But this team under the guidance of Warren Gatland are exactly that as they arrive with a 14-match unbeaten run and the prospect of being officially ranked the best side in the world if they avoid defeat.
While England's build-up has appeared muddled, Wales have been settled and have picked their strongest side. What could possibly go wrong?!