Postpublished at 12:02 Greenwich Mean Time 7 March 2020
England v Wales (12:05 GMT)
Right then, enough about permutations and postponements, it's time for some rugby as the players make their way to the field.
But first, let's hear the anthems...
Defending champions England top table with four wins from four
Lock Poppy Cleall scores hat-trick as England run in 10 tries
Katy Daley-McLean scores superb solo try
Vicky Fleetwood bags bonus-point fourth try before half-time
Wales bottom of table after fourth defeat
England's final match against Italy postponed because of coronavirus
Mantej Mann
England v Wales (12:05 GMT)
Right then, enough about permutations and postponements, it's time for some rugby as the players make their way to the field.
But first, let's hear the anthems...
England v Wales (12:05 GMT)
Becky Grey
BBC Sport at Twickenham Stoop
There are all sorts of last-minute changes going on in the Wales team.
Lisa Neumann and Caitlin Lewis have swapped wings, so Neumann is now wearing 11 and Lewis 14.
Lauren Smyth has been replaced on the bench by Lleucu George because of an injury sustained in training.
England v Wales (12:05 GMT)
So England can all-but claim another title in what could be their final game, with next week's trip to Italy postponed.
A fourth victory for the Red Roses will take them to 18 points, or 19 with a bonus point, which is still beatable by France if they win their two remaining matches with bonus points.
But with so much uncertainty over when, or IF, those postponed fixtures will be rearranged, victory for England will put them in a commanding position.
Meanwhile, a win for Wales will lift them off the bottom of the table.
England v Wales (12:05 GMT)
BBC Radio 5 Live Sports Extra
As well as following our riveting text coverage, you can also listen to the build-up and full match commentary over on BBC Radio 5 Live Sports Extra now.
Just follow the link at the top of this page.
Happy listening!
England v Wales (12:05 GMT)
England's Zoe Aldcroft was the only girl in a team of boys when she started playing rugby aged nine at her local club in Scarborough.
After three years, she was no longer allowed to play in a mixed team and faced a tough decision: travel three hours every Sunday to the nearest club with a girls' team or give up the sport she loved.
It seems her decision to stick at it has been vindicated but you can read more about her story here.
England v Wales (12:05 GMT)
In case you missed the team news in the week, here's a reminder of how both sides will line-up:
England: Scott; Thompson, Scarratt (c), Reed, McKenna; Daley-Mclean, Riley; Cornborough, Cokayne, Brown, Cleall, Aldcroft, Millar-Mills, Fleetwood, Beckett.
Replacements: Kerr, Botterman, Bern, Hunter, Harper, Hunt, Harrison, Venner.
Wales: Powell; Neumann, Jones, Lake, Lewis; Wilkins, Bevan; Pyrs, Jones, Hale, Evans, John, Butchers, Lewis, Lillicrap (c).
Replacements: Kelly, Hope, Lewis, Crabb, Lock, Lewis, Bluck, George.
England v Wales (12:05 GMT)
Becky Grey
BBC Sport at Twickenham Stoop
There may be split loyalties between these two but there’s a very heavy England weighting to the crowd here.
It looks like an attendance record might be broken today.
It’s a bit wordy, but the record for an England Women ticketed home game outside a World Cup is 10,545. Ticket sales had passed the 10,000 mark at the last count on Thursday. Should be a great atmosphere!
England v Wales (12:05 GMT)
With that news from Scotland, here's a look at the remaining fixtures in this year's Women's Six Nations:
Round Three
Italy v Scotland postponed
Round Four
Ireland v Italy postponed
England v Wales, 12:05 GMT, Saturday, 7 March, Twickenham Stoop, Twickenham
Scotland v France postponed
Round Five
Wales v Scotland, 13:10 GMT, Sunday, 15 March, Cardiff Arms Park, Cardiff
Italy v England postponed
France v Ireland, 13:30 GMT, Sunday, 15 March, Stadium Lille Metropole, Villeneuve-d'Ascq
While we're all set for rugby here, Scotland's game with France has been postponed after a Scottish player contracted coronavirus.
The player is being treated in "a healthcare facility but is otherwise well", says Scottish Rugby, while seven members of the Scotland playing and management staff are in self-isolation.
You can read the full story here.
England v Wales (12:05 GMT)
The Women's Six Nations is just one of several global events that have been disrupted because of coronavirus.
So much so that only one game is set to go ahead on the penultimate weekend of the championship.
But it's the big one and England can go a long way to successfully defending their title with a bonus-point win over Wales this afternoon.
Kick off at the Stoop is just over half an hour away...