Replacementpublished at 15 mins
England 0-8 Ireland
Dear oh dear.
England flanker Tom Curry hobbles from the field and Alex Dombrandt comes on. Dread to think what else could happen to England before the 80 minutes are up. It is not their day.
Summary
Ireland beat 14-man England to keep alive Six Nations title hopes
England lock Ewels sent off after 82 seconds for dangerous high tackle
James Lowe and Hugo Keenan score Ireland tries in frantic first half
England fight back to draw level at 15-15 after 60 mins
Late Jack Conan and Finlay Bealham tries give Ireland victory
England's title hopes over after second defeat in four games
Replacementpublished at 15 mins
Postpublished at 15 mins
England 0-8 Ireland
Swing Low, Sweet Chariot rings out as the crowd urges heroics from their side.
Ireland have possession though and again make enough space for James Lowe to prance down the left wing.
The visitors' rapid speed of play is proving a bit much for England but Joe Marchant grabs a turnover at the breakdown to halt their advances.
Postpublished at 14 mins
England 0-8 Ireland
England do look up for this.
They shove Ireland back, pretty impressive given they've got a winger in their pack after the red card.
Ellis Genge is bright red and screaming in celebration as the resulting penalty is booted down the field.
No trypublished at 17:03 Greenwich Mean Time 12 March 2022
England 0-8 Ireland
England needed that.
Raynal decides there was a knock-on by Jamison Gibson-Park and the hosts get some reprieve and a 5m scrum.
Postpublished at 17:02 Greenwich Mean Time 12 March 2022
England 0-8 Ireland
Caelan Doris barrelled through Harry Randall to go over on the left but Mathieu Raynal wants to check whether the ball had been knocked forwards out of Garry Ringrose's hands by England lock Maro Itoje.
Try reviewpublished at 17:01 Greenwich Mean Time 12 March 2022
Another one for Ireland? Or was there a knock-on?
Postpublished at 12 mins
England 0-8 Ireland
Again, Ireland stretch England's defence with ease and make a bit of progress down the right wing.
Dan Sheehan stumbles through a gap and Ireland are just a couple of metres out now.
Postpublished at 16:59 Greenwich Mean Time 12 March 2022
Matt Dawson
Former England scrum-half on BBC Radio 5 LiveIt was a red card all day long. As much as my phone is lighting up with people angry that it's ruined the game - there was no mitigation whatsoever.
England now have to show what they haven't for years and that is leadership in adversity. Enough of the high fives and taps on the backs - they need to step up.
Postpublished at 11 mins
England 0-8 Ireland
Very much not England's day so far. Ireland's Tadhg Furlong forces a scrum penalty as England's Ellis Genge hits the floor.
Ireland kick to the corner and will have another dangerous attacking platform.
Postpublished at 9 mins
England 0-8 Ireland
Iain Henderson grabs the ball in a maul, but it goes loose again and Henry Slade ends up with possession.
He goes for a kick, which swiftly ends up in touch and we'll come back for an England scrum. Wing Jack Nowell is going to have to pack down at flanker with Charlie Ewels sent off.
Oh, and James Ryan has failed his head injury assessment so Henderson will be staying on for the duration.
One word to sum up this first 10 minutes: chaotic.
Postpublished at 16:55 Greenwich Mean Time 12 March 2022
Matt Dawson
Former England scrum-half on BBC Radio 5 LiveIreland look like they are in the mood. They are looking slick regardless whether it's against 14 or 15 players. England can't do anything about Ireland's ruck speed.
Try - England 0-8 Irelandpublished at 6 mins
James Lowe
Beautiful stuff from Ireland.
The visitors spread England's defence and Dan Sheehan's pass sends Josh van der Flier through a gap.
James Lowe is rushing down the left wing, the flanker offloads and Lowe has plenty of room to go over.
Johnny Sexton misses his kick. Ireland are eight points and a man up after seven minutes.
Image source, Getty ImagesPostpublished at 5 mins
England 0-3 Ireland
As Eddie Jones has pointed out all week, Ireland were already favourites here.
England have a huge uphill battle ahead now but Harry Randall is up for the fight.
He takes a penalty quickly and makes it up to Ireland's 22 before the visitors claim back possession.
Postpublished at 16:52 Greenwich Mean Time 12 March 2022
England 0-3 Ireland
Mike Henson
BBC Sport at TwickenhamThe crowd were jeering as soon as they spotted the red card poised in referee Mathieu Raynal's hand.
The jeers continue as Johnny Sexton lines up the kick despite the message flashed up on the screens imploring respect for the kicker.
There is an even sharper edge to this.
Live nowpublished at 16:52 Greenwich Mean Time 12 March 2022
England 0-3 Ireland
BBC Radio 5 LiveCommentary is on BBC Radio 5 Live and BBC Radio Ulster. You can go for old-school radio, click play at the top of this page or give BBC Sounds a whirl. No excuse to miss out.
Penalty - England 0-3 Irelandpublished at 3 mins
Johnny Sexton
Johnny Sexton pops over the penalty to boos from the Twickenham crowd.
Postpublished at 16:51 Greenwich Mean Time 12 March 2022
England 0-0 Ireland
Michael Morrow
BBC Sport NI at TwickenhamWow.
Outrage around Twickenham.
Was that just a bit of a rush of blood to the head from Ewels? Courtney Lawes pleading with Mathieu Raynal that it's so early in the contest, but he's off.
Postpublished at 3 mins
England 0-0 Ireland
We're eighty-two seconds in!
England are going to have to play pretty much a full man with 14 men.
Eddie Jones' left eyebrow has raised so high it's in his hairline but laws on head contact have to be this strict nowadays.
Red cardpublished at 2 mins
England 0-0 Ireland
Wow. Charlie Ewels is off.
Game-changer.
Image source, Getty ImagesReplacementpublished at 16:49 Greenwich Mean Time 12 March 2022
England 0-0 Ireland
Iain Henderson is on.
The referee wants to have a look at Charlie Ewels' tackle on James Ryan, who has now gone off.
Ewels' head bashed straight into Ryan.