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Stefanos Tsitsipas beats Andy Murray 6-2 6-7 (7-9) 6-3 3-6 6-4 on Arthur Ashe in first round
British number one Dan Evans beats Brazil's Thiago Monteiro 6-3 6-7 (6-8) 6-4 6-1
Britain's Heather Watson and Harriet Dart make first-round exits
British number one Johanna Konta pulls out of tournament hours before her scheduled first-round match
Later: Cameron Norrie v Spain's Carlos Alcaraz
*Murray 6-2 6-7 (7-9) 6-3 2-5 Tsitsipas
Murray is fighting hard to ensure Tsitsipas has to try and serve out this set once again. He forces deuce, before a volley at the net hands him game point.
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Don Henry: Looks like the wheels have come off in the 4th set for Andy Murray but maybe he's just taking a wee breather before he clinches it in the 5th. I hope.
*Murray 6-2 6-7 (7-9) 6-3 2-5 Tsitsipas
Can Murray hold here and set up the opportunity to test the nerves of Tsitsipas one more time...
The Greek pulls the trigger with a stunning backhand - and another brings about set point.
Laura Robson
Former British number one on BBC Radio 5 Live Sports Extra
It looked like Tsitsipas just lost concentration and by the time he got it back Andy already had three break points.
I think he'll come out the next change of ends a bit more focussed.
Image source, Getty Images*Murray 6-2 6-7 (7-9) 6-3 2-5 Tsitsipas
Tsitsipas saves the first two break points with back-to-back aces, but it's not enough.
Murray gets one break back in the fourth. Is the comeback on?
Murray 6-2 6-7 (7-9) 6-3 1-5 Tsitsipas*
Surely not!
Tsitsipas nets with a volley and suddenly it's three break points for Andy Murray.
Murray 6-2 6-7 (7-9) 6-3 1-5 Tsitsipas*
Murray isn't done with this fourth set just yet and lands a smash of his own for 40-30.
A Tsitsipas miss seals Murray's first game of the set, but the third seed will now serve to take us to a fifth...
Laura Robson
Former British number one on BBC Radio 5 Live Sports Extra
The good thing is Andy has not spent too much energy in this set.
Russell Fuller
Tennis commentator on BBC Radio 5 Live Sports Extra
You feel both players are going through the motions here ahead of a decisive set.
*Murray 6-2 6-7 (7-9) 6-3 0-5 Tsitsipas
Andy Murray, serving to stay in the set, levels at 15-15 as Tsitsipas clips a forehand well beyond the baseline.
Murray then lures Tsitsipas in to the net with a drop shot, but the Greek takes the point with a smash for 15-30.
Herbert 6-3 6-4 4-6 3-6 3-6 Mannarino
France's Adrian Mannarino will play the winner of this one in the second round.
The world number 44 has just seen off compatriot Pierre-Hugues Herbert in five sets.
Laura Robson
Former British number one on BBC Radio 5 Live Sports Extra
I think Andy has still got the belief. The level has dropped slightly but he has played such good tennis to get to this stage of the match.
Look at how fast the momentum has changed in this set. Andy for sure still thinks he is very much in this even if it does go to five.
He has so much experience at Grand Slam level. You can't ever write him off.
*Murray 6-2 6-7 (7-9) 6-3 0-5 Tsitsipas
Stefanos Tsitsipas has found his rhythm in this fourth set.
A whopping one-handed backhand down the line moves the Greek to 40-0 and a hold to love is complete as Murray goes long. 5-0.
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Tom: I have to get up at 5.30am tomorrow- Andy, you’re killing me!
Laura Robson
Former British number one on BBC Radio 5 Live Sports Extra
It's hard to know which way this match is going to go now.
I feel like Andy is still the better player but does he have the energy one last time to come back and take this in four?
If it goes to five you have to lean towards Tsitsipas so many times but Andy has proved us wrong so many times.
Nobody thought he would be in this position.
Murray 6-2 6-7 (7-9) 6-3 0-4 Tsitsipas*
We're approaching three and a half hours of play on Arthur Ashe. It's draining stuff out there in the heat.
Murray is in trouble on serve as Tsitsipas edges 15-40 up, and the former champion whips a forehand into the net to fall a double break behind. A fifth set beckons.
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Sam Shatterface: Seeing Andy play like this with one hip, you have to wonder what could have been. He was struck down at world no. 1, playing at his peak. He probably would have at least 7/8 slams by now. No doubt one of the very very best ever!
*Murray 6-2 6-7 (7-9) 6-3 0-3 Tsitsipas
Andy Murray has been calling for the lights to come on, and they do just that.
He has his wish, now can he get himself back into this set or are we destined for a five-set blockbuster?
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Therasa Marshall: Couldn’t handle a stressful Andy Murray match this evening but from the updates it sounds like vintage Andy!! Come on Andy!!
Sarah Knowles: Woohooo! Come on, Andy!
Laura Robson
Former British number one on BBC Radio 5 Live Sports Extra
You have to think this one is going to five sets now.
There has been a bit of a drop in energy from Andy. He has done so well to keep the intensity high.
But in every five-set match you're going to have highs and lows.