Italy head off into the night celebrating a first home win over Wales in 18 years, while Wales are left to digest a 14th successive Test defeat and an all-time lowest world ranking of 12th.
No doubt Warren Gatland is going to face more tough questions again this week.
'I can understand people's frustration' - Gatlandpublished at 16:44 Greenwich Mean Time 8 February
16:44 GMT 8 February
FT: Italy 22-15 Wales
Image source, Huw Evans Picture Agency
Wales head coach Warren Gatland told S4C: "I know how hard we are working.
"I can understand people's frustration and we are frustrated and disappointed as well because we created opportunities but we have made mistakes and the penalty count was disappointing.
"As a coaching team and players they are not hard fixes but we need to make sure we focus in those key moments."
Postpublished at 16:31 Greenwich Mean Time 8 February
16:31 GMT 8 February
FT: Italy 22-15 Wales
James Hook Former Wales fly-half on BBC Radio Wales
Wales looked like a poorly coached team. We went into the game to kick but other than that there was no deception outside.
When we did have the ball we did not get over the gain line. We looked lost and players looking around for others to do things and nothing was happening.
The scoreline flattered Wales and Italy were completely dominant.
'Nothing is off the table' - Biggarpublished at 16:25 Greenwich Mean Time 8 February
16:25 GMT 8 February
FT: Italy 22-15 Wales
Former Wales fly-half Dan Biggar on ITV: "If you look at the games they have lost in the last 12 months, today was the poorest performance in that run.
"It is hard to say because there are a lot of good people there but it is just not working. Whatever is going on Monday to Friday is not being transferred to the pitch on a Saturday.
"Wales have Ireland coming to Cardiff in two weeks time, they travel to Scotland and welcome England.
"This team looks one that is shot of belief and confidence. We keep getting asked the same questions but what are the answers. I am not quite sure. The curve has been downward."
On Warren Gatland's future, Biggar added: "That is for people on a higher pay grade than me to decide. I don't think anything is off the table at the moment, it can't be. It can't carry on.
"It is such a shame because there are so many good people there who have had success previously but clearly what is happening there in the week is not working."