Nick Tompkins has left the field for a head injury assessment.

Josh Hathaway comes on - he goes to the wing, with Josh Adams moving to centre.

Italy are penalised at the scrum.

Tomos Williams sees the space but his kick has too much on it and it's a goal line drop out for Italy.

Gwyn Jones
Former Wales captain on S4C

It's brilliant skill from Blair Murray under the high ball. That kick was measured much better from Wales.

Wales have won that kicking battle, it's a great take from Blair Murray.

But the pass out to Josh Adams is forward and it's an Italy scrum, sloppy from Wales.

Gwyn Jones
Former Wales captain on S4C

Wales need to keep their kicks outside of Italy's 22. It's small margins but it's really important.

Matt Lloyd
BBC Sport at Stadio Olimpico

This is going to be a match for the purists.

Expect a lot - and I mean, a lot - of kicking in these conditions.

Wales could miss Liam Williams under these high balls.

Ian Gough
Former Wales international on BBC Radio Wales

Wales need to solve those early line-out issues, especially in the wet conditions.

Image source, Getty Images

A wobble in Wales' lineout, they regather but they've lost 10 metres.

Scott Williams
Former Wales centre on BBC Radio Cymru

Wales need to start well.

Looking back, the big, high-pressure games is when we have played well, which will have been spoken about.

James Hook
Former Wales fly-half on BBC Radio Wales

That was a decent strike. Allan kicked well at Murrayfield last weekend and kept them in the game.

The full-back showing his prowess at the tee, just like he did at Murrayfield last weekend.

Freddy Thomas is penalised for offside.

Italy decide to go for posts.

Plenty of kicking going on in these early exchanges.

The aerial battle is going to be key today.

Caryl James
Former Wales wing on BBC Radio Cymru

It's brilliant from Tomos Williams, the kick is excellent. Josh Adams had to go flat out to try and claim the ball, which is slippy because of the conditions.

James Hook
Former Wales fly-half on BBC Radio Wales

It was a great kick from Tomos Williams but it just did not sit up for Josh Adams.

That will be the bit of luck Wales need today if they are going to win.

Great vision from Tomos Williams, he puts a cross-field kick in and Josh Adams is just inches away from gathering it.

Matthew Carley blows his whistle and Ben Thomas gets us under way in Rome.

Here goes.

As kick-off approaches, here's a reminder of how Italy and Wales line-up in Rome.

Italy: Allan; Capuozzo, Brex, Menoncello, Ioane; P Garbisi, Page-Relo; Fischetti, Nicotera, Ferrari, N Cannone, Ruzza, Negri, Lamaro, L Cannone

Replacements: Lucchesi, Rizzoli, Riccioni, Lamb, Zuliani, Vintcent, A Garbisi, Trulla.

Wales: Murray; Rogers, Tompkins, James, Adams; B Thomas, Tomos Williams; G Thomas, Lloyd, H Thomas, Rowlands, F Thomas, Botham, Morgan (c), Faletau.

Replacements: Dee, Smith, Assiratti, Teddy Williams, Wainwright, R Williams, Edwards, Hathaway.

Image source, Getty Images

Italy head coach Gonzalo Quesada: "Wales have had a day more preparation than us and that is worth gold at this stage of the competition.

"Not a single one of us thinks that this will be an easy match. It will be a fierce battle against a team that will be very different from that of 2024, a team with a lot of experience and pride."

Wales head coach Warren Gatland: "When you're looking at picking a squad, if you make three or four changes, do those players feel like they've been made the scapegoat?

"There's a couple of forced changes, but there's an opportunity for those guys to go out and do what we did well last week.

"Also an opportunity to fix some things to change the performance."

Ian Gough
Former Wales lock on BBC Radio Wales

It is a hard one for Freddie Thomas because his preparation has been different this week.

He has been parachuted into the team this morning and all his nerves will be there.