Southampton have won just one of their last 15 Premier League games against Man City (D3 L11), a 1-0 home win in July 2020.

Man City won the reverse fixture 1-0 against Southampton, but haven’t kept a clean sheet in consecutive league meetings with the Saints since doing so in both meetings of the 2014-15 campaign.

Since the 2004-05 season, Man City have lost just three of their 25 Premier League meetings with Southampton (W17 D5), though all three of those defeats have come at St. Mary’s.

Manchester City are unbeaten in their last 29 Premier League games against sides starting the day bottom of the table (W24 D5) since a 2-1 loss at West Brom in December 2008. The Citizens have won their last 12 in a row by an aggregate score of 44-1.

Southampton have lost 28 Premier League games this season, while defeat here would equal the highest number of losses in a 20-team top-flight campaign (also Sunderland in 2005-06, Derby in 2007-08 and Sheffield United in 2020-21).

Manchester City have won their last four Premier League games, their joint-longest winning run of the season. They’re looking to win back-to-back away league games for the first time since August.

Southampton have dropped more points from winning positions than any other team in the Premier League this season (28). If they lead but fail to win this match, it will be the first time they’ve lost 30+ points after going ahead in a single campaign in the competition.

Southampton have conceded 82 Premier League goals this season. Only three times before have they conceded more in a single league campaign in their history – 85 in 1952-53, 92 in 1966-67 and 83 in 1967-68.

Against no side has Man City’s Kevin De Bruyne been directly involved in more Premier League goals than he has against Southampton (14 – 4 goals, 10 assists). Only Ryan Giggs (12 vs Man City and 12 vs Newcastle) and Cesc Fàbregas (11 vs Tottenham) have more assists against an opponent in the competition than his 10 vs Saints.

Man City’s Jérémy Doku has completed more dribbles than any other player in the Premier League this season (102), while he also has the highest dribble success rate of anyone to attempt at least 60 (61.5%).