Arsenal manager Arteta had to rotate his squad, with Kai Havertz missing through illness and captain Martin Odegaard also suffering and only well enough for substitute duty.
The Gunners are already trying to deal with the loss of Bukayo Saka who is out of action with a serious hamstring injury, yet they had by far the better of the opening stages of this game.
The main criticism will be that despite that superiority, Arteta's side struggled to create clear-cut chances.
Arteta has turned to teenager Nwaneri as he looks to fill the gap left by Saka's absence, and it is a big challenge for a player so young.
The youngster was sharp and trusted by his team-mates in possession on the south coast but took some unnecessary risks, the sort that will be part of his journey as he progresses into a senior player and gains more experience.
Nwaneri's goal made him the first player to score more than one goal in the Premier League for Arsenal before their 18th birthday.
Arteta was pleased with the showing from the youngster, but Nwaneri was withdrawn at half-time with what the manager described as "muscular issues" and it remains to be seen when he can play again.
The team's failure to complete their job will be a concern, and Arsenal are in danger of slipping out of the title race if they are unable to apply pressure on Liverpool, whose lead feels increasingly comfortable on days like this.