Team news
Arsenal winger Bukayo Saka is ready to return after three months out with a torn hamstring, and he could even start.
Jurrien Timber has recovered from illness but fellow defender Riccardo Calafiori faces a few weeks out with the knee injury he sustained on international duty.
Fulham head coach Marco Silva reported nothing other than "knocks and tiredness" among his squad in the wake of their FA Cup quarter-final defeat by Crystal Palace at the weekend.
Former Gunners player Reiss Nelson is among the long-term absentees with a hamstring injury.
Match facts
Head-to-head
Arsenal have never lost in 31 home league fixtures against Fulham (W24, D7). It's the most home games one side has played against another without ever losing in English league history.
However, the Gunners have not won any of the past three meetings (D2, L1).
Arsenal
Arsenal have lost just one of their last 19 Premier League matches (W11, D7).
Mikel Arteta's side have earned 20 points in London derbies this season, more than any other side.
Their Premier League games this season are averaging 23.6 shots per match (13.9 for, 9.7 against), the lowest of any side in the division this season.
The Gunners have kept 17 clean sheets this season in all competitions and restricted their opponents to less than 0.50 xG in 11 of their 29 Premier League games – more than any other side.
They have scored 27 goals from corners in the top flight since the start of last season, more than any other side.
Arsenal have won all seven of their Premier League games on 1 April by an aggregate score of 25-3.
Fulham
Fulham's run of three consecutive away wins came to an end when they lost at Brighton earlier this month.
They could equal their club record of five London derby league wins in a season, set in 1931-32 and matched in 1947-48 and 2000-01.
Marco Silva averages 1.3 points in London derbies while at Fulham, the best of any manager to have taken charge of at least 10 such fixtures with the club in the Premier League.
An unrivalled 13 of Fulham's 43 Premier League goals this season have been scored by substitutes.
Antonee Robinson has made 50 interceptions in the Premier League this season, the joint-highest total along with Liverpool's Ryan Gravenberch.
