Who else is playing?published at 19:02 Greenwich Mean Time 16 February 2017
As ever it's a busy night across Europe with 16 ties across three kick-off times and multiple time zones.
The biggest game under way for those in the UK is Tottenham's trip to Gent.
The score is currently 0-0 and you can follow full commentary here. The second half has just begun.

Could Edinbe heading for a trophy?
In the rest of tonight's second wave, Roma face Villarreal in the pick, with both sides heavily backed to win the trophy. Behind the Premier League duo, that is.