Mourinho says he has "no regrets"
Ben Yedder broke deadlock 87 seconds after coming off bench
Sevilla into Friday's quarter-final draw
Man Utd play Brighton in FA Cup on Saturday
Man Utd 0-2 Sevilla (agg 0-2)
Ally McCoist
Former Scotland striker on BBC Radio 5 live
It's a shocking goal to conceded, a free header. Ashley Young loses Wissam Ben Yedder at the far post and David de Gea makes a valiant attempt to keep it out but it spins over the line.
Manchester United look as though they are out.
Man Utd 0-2 Sevilla
That is surely game over for Manchester United now. Two away goals from Sevilla means the hosts would need three goals in the last 12 minutes to see them through.
Wissam Ben Yedder
What an impact! That is what you call super sub.
Wissam Ben Yedder heads it in from the far post and despite David de Gea's efforts to clear it off the line after it comes down off the crossbar, it's in.
There is a slight delay before the goal is given - but there is no doubt the ball crossed the line.
Image source, Getty Images
Image source, ReutersMan Utd 0-1 Sevilla
Here come the changes for Manchester United.
Jesse Lingard and Antonio Valencia are off. Anthony Martial and Juan Mata are on.
Man Utd 0-1 Sevilla (agg 0-1)
Ally McCoist
Former Scotland striker on BBC Radio 5 live
What a finish. It's a brilliant move. Manchester United gave the ball away again, we've seen it so often tonight. It's been so poor.
The secret to the goal is Wissam Ben Yedder takes a slight touch and moves it and hits it early.
That is a great finish.
Man Utd 0-1 Sevilla
As it stands, Sevilla are through to the quarter-finals of the Champions League. Manchester United need two goals to stay in the competition.
Wissam Ben Yedder
He's only been on a matter of minutes but Wissam Ben Yedder has made all the difference so far! He controls the ball well, takes it on his right foot and fires it into the bottom corner.
Game-changer.
Image source, ReutersMan Utd 0-0 Sevilla
Wissam Ben Yedder is involved straight away. His movement is excellent and Pablo Serabia tries to find him with a long ball over the top and through the middle.
It wasn't too far off from finding its target.
Man Utd 0-0 Sevilla (agg 0-0)
Ally McCoist
Former Scotland striker on BBC Radio 5 live
That came from nothing. Paul Pogba was about 25-yards out and he just unleashed one.
Man Utd 0-0 Sevilla (agg: 0-0)
Chris Bevan
BBC Sport at Old Trafford
"Attack, attack... attack, attack, attack"
It's clear what the United fans want their team to do.
Will Jose listen to them?
Image source, EPAMan Utd 0-0 Sevilla
Ben Yedder comes on for Sevilla. It's Luis Muriel who goes off. He's not had his shooting boots on tonight...
Man Utd 0-0 Sevilla
Paul Pogba shoots from a long way out and it is a good strike with his left foot. Sergio Rico looked to have it covered but it was a good effort.
Image source, ReutersRoma 1-0 Shakhtar Donetsk (agg 2-2)
Roma still have the advantage at the Stadio Olimpico and Edin Dzeko is running the show.
Since his goal, he's had several chances to double his side's lead, including one curling effort which glanced just inches wide of the post.
With 20 minutes remaining, the Italians have certainly upped their game and the last eight is beckoning.
Image source, ReutersMan Utd 0-0 Sevilla
Franco Vazquez fires a cross in from the left and it's a dangerous one. David de Gea has to pounce on it and he does - but that could have gone badly for United.
#bbcfootball or text on 81111
Betiku: Does Jose Mourinho realise he has to score to qualify? If Sevilla get one goal, it's over.
Theo: Paul Pogba... been on for 5 minutes. Given the ball away 3 times already. Standard.
Pete: How Mourinho has turned Sanchez into the player he now is a real head-scratcher. We are turning into a more affluent version of 1980s Wimbledon.
Man Utd 0-0 Sevilla
Sevilla win a free-kick in a useful area but Pablo Sarabia's delivery isn't great.
His teammates didn't do much to attack it but it was a waste.
Man Utd 0-0 Sevilla
But it's a poor effort. Still goalless at Old Trafford.
Image source, EPAMan Utd 0-0 Sevilla
Marcus Rashford cuts inside on his right and skips past Sergio Escudero before being dragged back to earn a free-kick.
He's standing over it too.
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Dave W: Juan Mata is the only really creative midfielder. Need him on with 25 minutes left.
Bill: It’s ok to criticise the manager but these lazy multi-million pound footballers must shoulder some responsibility. It’s the same every game.
Image source, Getty ImagesMan Utd 0-0 Sevilla
A sloppy pass from Paul Pogba is picked up by Joaquin Correa in midfield. That's not a great start from the Frenchman.