This is a fine game. Pierre-Emerick Aubameyang puts in a telling cross which is well cut out and then from the corner Alexandre Lacazette's header is superbly saved by Alex McCarthy. The flag was up though - wouldn't have counted...

Francis Edwards: Finally Klopp has realised that in order to really challenge City he can’t play three defensive midfielders. Glad Henderson is the one to drop out, he really does very little apart from occasionally shout at the ref.

Danny Mills
Former England defender on BBC Radio 5 live

That was an incredible spot by Sian Massey-Ellis on the far side. I don't often praise officials but that was a great spot, to see through all those bodies. Shane Long was offside.

Jurgen Klopp makes three changes to the side which beat Bournemouth 4-0 last Saturday as Sadio Mane returns from injury to replace Xherdan Shaqiri in the starting line-up.

Dejan Lovren and Nathaniel Clyne, who makes his first Premier League start since May, both come in, while Joel Matip and James Milner drop out of the matchday squad.

Liverpool starting XI: Alisson; Clyne, Lovren, van Dijk, Robertson; Wijnaldum, Fabinho, Keita; Salah, Firmino, Mane.

Subs: Mignolet, Moreno, Camacho, Lallana, Henderson, Shaqiri, Sturridge.

Image source, bb

Jose Mourinho makes two changes to the side which beat Fulham 4-1 last weekend, as Victor Lindelof and Matteo Darmian both start.

Phil Jones and Juan Mata, who is named on the bench, miss out, while Paul Pogba and Anthony Martial are also substitutes.

Manchester United starting XI: De Gea; Dalot, Smalling, Lindelof, Darmian; Herrera, Matic; Young, Lingard, Rashford; Lukaku.

Subs: Romero, Bailly, Pogba, Mata, Martial, Valencia, Fellaini.

Shane Long scores! No!

It is a very good call too. He was offside from an original header from Maya Yoshida, Bernd Leno claws it out and Long scrambled it in from about a yard out. He sprinted halfway down the touchline in celebration too. Poor guy.

Into the last 15 minutes. Brighton trying to build up a head of steam, can Chelsea hold on?

Liverpool: Alisson, Clyne, Lovren, van Dijk, Robertson, Wijnaldum, Fabinho, Keita, Salah, Firmino, Mane. Subs: Henderson, Sturridge, Moreno, Lallana, Mignolet, Shaqiri, Camacho.

Man Utd: de Gea, Darmian, Smalling, Lindelof, Dalot, Lingard, Matic, Ander Herrera, Young, Rashford, Lukaku. Subs: Bailly, Pogba, Mata, Martial, Romero, Valencia, Fellaini.

Referee: Martin Atkinson (W Yorkshire)

Liverpool make four changes from the team which beat Napoli, there's no James Milner. Dejan Lovren and Nathaniel Clyne start in defence.

Manchester United make 10 changes from the defeat in Valencia. Take your pick how they are lining up, could be a back five, maybe more. Paul Pogba is on the bench.

Full team news to come.

Maurizio Sarri is fuming on the touchline about something to do with Ruben Loftus-Cheek's socks. The modern manager's inbox is always full.

Alex Iwobi is a new man this season, and he does wonders down near the corner flag to somehow play the ball off his standing leg and flick it past a defender to take him into th ebox. It was classy, but seconds later he's replaced by Mesut Ozil.

Image source, Reuters

Danny Mills
Former England defender on BBC Radio 5 live

Southampton have been better today. They've had more spirit about them and the manager's had an impact already in terms of attitude and self-belief.

But on the balance of play and the quality they have in the side, if anyone is going to nick it then it's going to be Arsenal.

Can Brighton find a way back through then? About 25 minutes left at the Amex. Ruben Loftus-Cheek replaces Pedro for the visitors.

We will have team news from Anfield shortly.

Guy Mowbray
Match of the Day commentator

A Christmas quiz question: what went up from 35% in 2017 to 38% last year? Answer: Manchester United's meagre possession away to Liverpool.

To balance things, a follow-up could be: what hasn't happened in the clubs' last eight Premier League meetings? A Liverpool win.

United's defence surely hasn't been solid enough to sit back and set up for a third 0-0 draw at Anfield in a row - but if Jose Mourinho challenges his biggest stars to step up and match the league leaders, the risk could override the chance of reward.

A test of Liverpool's ever-improving title credentials. A test of United's togetherness. A test of the seasonal concept of peace and goodwill to all men!

Unlucky! Wonderful strike from Marcos Alonso, from the edge of the area, lovely drive and it stings the outside of the far post and bounces to safety.

Fine effort.

Southampton now having a good spell, Laurent Koscielny is in a bit of a mess and he goes into the book for taking out the last man. Just outside the area.

Danny Mills
Former England defender on BBC Radio 5 live

Pierre-Emerick Aubameyang's first touch let him down and forced him to go wide.

But, again, Arsenal are looking very dangerous going forward.

They're really starting to ramp up the pressure. Territory and possession, it's all Arsenal now.

Khan Karn: Ridiculously lucky for Arsenal.

Good game to watch now - Pierre-Emerick Aubameyang is free on the left straight from kick-off, he finds Alex Iwnobi who curls it over the top.

Ralph Hasenhuttl is a character, pacing the touchline in animated style.