Sho: When you look at the United starting line-up and the formation, then look at the bench, you wonder what's happened in this third season where we were supposed to be challenging. It's such a mess.

Oliver Camp: Predicting a cagey half hour and then the game will spring into action: 3-2 City at full time. KDB to score, not only for my Fantasy Team...

Michael Reid: Ole is by far more more of a negative manager for United that Jose ever was. Hopefully the negative tactics pay off!

This is the last weekend of Premier League action for two weeks as it makes way for yet another international break.

Personally, I don't think there are enough international breaks in the football calendar*

*I'm going to scream if there's another international break.

Image source, .

Nine of Manchester United's 27 goals in all competitions this season have come in the 80th minute or later.

Three of Cristiano Ronaldo's nine goal since re-signing have come in the 81st (Atalanta - 20 Oct), 91st (Atalanta - 2 Nov) and 95th minutes (Villarreal - 29 Sept).

Simon Stone
BBC Sport

Image source, .

Last weekend's home defeat by Crystal Palace has left Manchester City's title defence in trouble.

Despite beating Chelsea at Stamford Bridge in September, they are now five points adrift of Thomas Tuchel's side. In addition, their goal difference is nine less that Chelsea.

With Kevin de Bruyne not yet at his best and Jack Grealish producing in bursts rather than on a consistent basis since his record £100m transfer from Aston Villa, Pep Guardiola definitely has issues to deal with.

BBC Radio 5 Live

Former Manchester United and Manchester City keeper Peter Schmeichel is alongside John Murray at Old Trafford for updates on BBC Radio 5 Live.

Build-up to today's games start at 12:00 GMT with Mark Chapman in the hot seat.

As well as updates from Old Trafford, there is full match commentary of Chelsea against Burnley from 15:00.

Sports Report at 17:00 is followed by 606 at 18:00 with Robbie Savage and Chris Sutton taking your calls, plus Brighton v Newcastle updates.

Image source, Getty Images

Henry Winter
Chief Football Writer for the Times on BBC Radio 5 Live

Ole Gunnar Solskjaer has to get a result today. A draw will probably suffice given how good Manchester City are but he cannot risk a painful defeat. He is missing Raphael Varane and Edinson Cavani.

Cavani is a big miss in particular because he does that amazing running around Cristiano Ronaldo up front and helps make this new 3-4-1-2 system work.

Jack Grealish dropped to the bench? Two keepers on the bench.

Interesting team news from Manchester City.

Image source, BBC Sport

Manchester United manager Ole Gunnar Solskjaer makes three changes to the side that started the 2-2 draw with Atalanta in the Champions League on Tuesday. Raphael Varane is out with a hamstring injury, Paul Pogba is suspended and Marcus Rashford drops to the bench.

Victor Lindelof returns in defence while Fred and Mason Greenwood also start but there is no place among the substitutes for Edinson Cavani who has picked up an injury.

Man Utd XI: De Gea, Wan-Bissaka, Bailly, Lindelof, Maguire, Shaw, Fernandes, McTominay, Fred, Greenwood, Ronaldo.

Subs: Henderson, Martial, Rashford, Lingard, Dalot, Sancho, Telles, Matic, Van de Beek.

Image source, bbc sPORT

Manchester City boss Pep Guardiola also makes three changes to the side that began the 4-1 win over Club Bruges in the Champions League.

Aymeric Laporte is suspended while Jack Grealish and Riyad Mahrez drop to the bench as Kevin de Bruyne, Ruben Dias and Gabriel Jesus all start.

Man City XI: Ederson, Walker, Dias, Stones, Cancelo, Silva, Gundogan, Rodri, De Bruyne, Jesus, Foden.

Subs: Steffen, Carson, Ake, Sterling, Grealish, Zinchenko, Fernandinho, Mahrez, Palmer.

Michael Brown
Former Man City midfielder on BBC Radio 5 Live

Harry Maguire has done a very good job for United in different times. He’s a leader in the dressing room. When you come back into the side you look in front of him – they can’t get a system that helps him. At United when you don’t get a result, all the mistakes are highlighted. The system will help him if they stick to a back three.

There are reports that Edinson Cavani has picked up an injury, while Kyle Walker and Victor Lindelof are both doubts.

Team news is minutes away.

Image source, PA Media

Oh dear.

Mark Lawrenson
BBC football expert

Manchester United's win over Tottenham last weekend was a good result but if you actually watched the game, Spurs were absolutely hopeless. Tuesday's 2-2 draw with Atalanta was a better gauge of where Ole Gunnar Solskjaer's side are at as a team.

It was United's 'big three', as I call them, of Cristiano Ronaldo, Edinson Cavani and Bruno Fernandes, who did for Tottenham and scored in the Champions League too, but they shipped some bad goals in Italy and I can't see them keeping Manchester City quiet.

Lawro's prediction: 1-2

Image source, .

Manchester City have finished above Manchester United nine times in the past 10 seasons and are currently three points above them in the table.

BBC Radio 4

Former Manchester United midfielder Lou Macari, speaking on BBC Radio 4's Today programme: "The Liverpool game was a disaster. We were just like statues and before we knew it we were 4-0 down. I'm sure it will be a lot better than that and the record against Manchester City is OK. Ole needs to win. I hope the players realise he needs to win to keep his job, but I'm going for a 2-2 draw.

Since Manchester United and Manchester City were last in Premier League action, Nuno Espirito Santo has been sacked by Spurs, Unai Emery has ruled out taking over Newcastle, Antonio Conte has returned to the England - and a new ball "inspired by real life superheroes" has been unveiled.

Can you spot the billboard advertising the signing of Carlos Tevez that irked Manchester United all those years ago? Shots fired...

How do you get fans on your side ahead a huge derby? Tell them their rivals will never be a bigger club in terms of historical dominance.

Here's Ole Gunnar Solskjaer setting the tone for the derby.

Simon Stone
BBC Sport

Image source, Reuters

With Ole Gunnar Solskjaer's position as Manchester United boss still under intense scrutiny and Chelsea piling the pressure on in the Premier League title race, the 186th Manchester derby at Old Trafford will have far more riding on it than just local pride.

The game itself is framed by United's horrendous 5-0 home defeat by Liverpool a fortnight ago, which has generated so much uncertainty around Saturday's hosts.

Another loss against a major rival so soon afterwards will be difficult for United - and Solskjaer - to swallow. But defeat is not without its consequences for Manchester City either given their early-season form.

Read more on Simon Stone's thoughts about the Manchester derby here.

Image source, Getty Images

As well as a red hot Manchester derby, leaders Chelsea can extend their lead at the top, managerless Newcastle are seeking to climb away from trouble, in-form Wolves are looking to make it 16 points out of 18, while rock bottom Norwich are desperate for a first win.

12:30: Manchester United v Manchester City

15:00: Brentford v Norwich City

15:00: Chelsea v Burnley

15:00: Crystal Palace v Wolves

17:30: Brighton v Newcastle United