Rob Holding is doing exactly what he was brought on for - winning headers, clearing danger.

United keep plugging away, but this game is surely beyond them now.

Rob Holding clears a cross from the left.

Not sure what difference this will make?

Juan Mata on for Bruno Fernandes, who has had a 'mare.

Another booking. Victor Lindelof the latest for a foul.

A ball over the top is designed to release Cristiano Ronaldo, but he can't gather. Time slipping away for the visitors.

Mark Schwarzer
Former Middlesbrough & Fulham keeper on BBC Radio 5 Live

The only thing I'd say in Fernandes' defence is he was in control, he wasn't off the ground. But it wasn't a nice challenge.

The yellow cards continue to come.

Mohamed Elneny is booked for catching Scott McTominay on the boot.

On comes Jesse Lingard and Marcus Rashford for Manchester United. Nemanja Matic and Anthony Elanga off.

Shuffling deckchairs on the Titanic.

Video Assistant Refereepublished at 76 mins

76 mins

Arsenal 3-1 Man Utd

Oof, that is naughty. He has left his boot in badly and caught Nuno Tavares on the shin. No touch on the ball at all.

VAR takes the decision that a yellow is enough. He is a lucky, lucky lad.

Bruno Fernandes has had a shocker of an afternoon. He is booked for leaving in a boot on Nuno Tavares.

It might get worse as well, you know. VAR is going to look at this...

Image source, EPA

Chris Bevan
BBC Sport at Etihad Stadium

Manchester City make six changes from the side that beat Brighton on Wednesday.

Ruben Dias, who returned from a hamstring injury when he came off the bench for the second half against the Seagulls, makes his first start since 1 March.

Oleksandar Zinchenko gets the nod at left-back, while Fernandinho comes into midfield to play alongside Rodri and Kevin de Bruyne.

Gabriel Jesus, Raheem Sterling and Jack Grealish form the attack, and will be hoping to link up better than they did when they started at Wembley in last weekend’s FA Cup semi-final.

Man City XI: Ederson, Cancelo, Dias, Laporte, Zinchenko, Rodri, Fernandinho, De Bruyne, Sterling, Grealish, Jesus.

Subs: Steffen, Ake, Gundogan, Bernardo, Mahrez, Foden, Egan-Riley, Mbete, Palmer.

Image source, BBC Sport

Watford make three changes from the side that were beaten by an injury-time goal by Brentford last weekend.

Jeremy Ngakia starts at right-back for his first game since the end of February, Tom Cleverley is back in midfield and Joshua King returns up front.

Kiko Femenia and Juraj Kucka are out with minor knocks and Joao Pedro drops to the bench.

Watford XI: Foster, Ngakia, Samir, Kabasele, Kamara, Sissoko, Cleverley, Louza, Sarr, Dennis, King

Subs: Bachmann, Ekong, Pedro, Masina, Sema, Nkoulou, Cathcart, Gosling, Kayembe

Image source, BBC Sport

Fifteen minutes left for Manchester United to salvage something here.

If they fail to do so, that is surely a Champions League place gone.

Arsenal were going to take Eddie Nketiah off, but Bukayo Saka is down, so there may be a change of plan now.

Rob Holding is the man coming on.

Yep, it is for Saka.

Mark Schwarzer
Former Middlesbrough & Fulham keeper on BBC Radio 5 Live

There is a lot of pace on that, and it came through a crowd of players. It is not the first time where Man Utd stood and watched.

A lovely strike, very little back lift and a lot of power. Then the celebrations began.

Image source, Reuters

It was all Manchester United prior to that goal.

But the potential revival looks over.

Penny for Bruno Fernandes' thoughts.

Brendan Rodgers rotates things a little for Leicester with one eye on Thursday's Europa Conference League semi-final against Roma.

It's four changes for the Foxes as Jonny Evans, Ricardo Pereira, Harvey Barnes and Kelechi Iheanacho miss out after starting in the draw at Everton.

Patson Daka and Ademola Lookman come into the attack, Caglar Soyuncu is in at the back. as is James Justin.

Leicester XI: Schmeichel, Justin, Fofana, Soyuncu, Tielemans, Maddison, Dewsbury-Hall, Mendy, Castagne, Daka, Lookman.

Image source, .

Aston Villa arrive on a run of four defeats in a row.

Lucas Digne is out with injury for Villa and their only other change from the 4-0 defeat to Tottenham sees Danny Ings drop to the bench.

Leon Bailey and Ashley Young come in.

Aston Villa XI: Martinez, Cash, Konsa, Mings, Luiz, McGinn, Watkins, Young, Coutinho, Bailey, Ramsey.

Image source, .

There is just one change to the Norwich side who suffered a narrow defeat to Manchester United.

Christoph Zimmermann comes in for Ben Gibson, who drops to the bench. Brandon Williams is a substitute too.

Norwich XI: Krul, Byram, Hanley, Zimmerman, Dowell, Normann, Rashica, Lees-Melou, Pukki, McLean, Giannoulis.

Image source, BBC Sport

There are four changes to the Newcastle side from the victory over Crystal Palace after manager Eddie Howe said he would "freshen things up".

Fabian Schar, Jonjo Shelvey, Miguel Almiron and Chris Wood all drop to the bench.

In comes Jamaal Lascelles, Emil Krafth, Jacob Murphy and Joe Willock. Joelinton is making his 100th Premier League appearance.

Newcastle XI: Dubravka, Lascelles, Joelinton, Saint-Maximin, Targett, Krafth, Murphy, Willock, Burn, Longstaff, Guimaraes.

Image source, BBC Sport

Man Utd is the third team to hit the woodwork as many as three times in a Premier League match this season, after Manchester City (3, away at Southampton 1-1) and Brighton & Hove Albion (3, at home versus Leeds 0-0).

United remain on top.