Postpublished at 11:29 British Summer Time 27 August 2022
Will Casemiro start or will he begin his Manchester United career on the bench?
Team news from St Mary's will be dropping any moment now.
FT: Arsenal 2-1 Fulham - Gunners dominating but spurn chances
Gabriel loses possession as Mitrovic take advantage but Odegaard levels and Gabriel scores
FT: Liverpool 9-0 Bournemouth: Diaz (2), Elliott, Alexander-Arnold, Firmino (2), Van Dijk, Mepham own goal & Carvalho
FT: Man City 4-2 Crystal Palace - Stones own goal and Andersen header, but Silva pulls one back and Haaland scores treble
FT: Brentford 1-1 Everton - Gordon opens scoring but Janelt levels
FT: Chelsea 2-1 Leicester - Gallagher sent off for Chelsea but Sterling scores twice, Barnes pulls one back
FT: Brighton 1-0 Leeds - Gross with opener
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Gary Rose
Will Casemiro start or will he begin his Manchester United career on the bench?
Team news from St Mary's will be dropping any moment now.
Southampton v Man Utd (12:30 BST)
Nigel Reo-Coker
Former West Ham midfielder on BBC Radio 5 Live
It wouldn't be a bad thing for Casemiro to sit out the first game to understand and watch the tempo of the Premier League. Sometimes people don't realise the big change and the differences of coming from Spain, and how physically demanding the Premier League is. I think he has to understand that.
Southampton v Man Utd (12:30 BST)
Darren Fletcher
BBC Radio 5 Live's The Friday Football Social
It will be interesting to see what Erik ten Hag does with Casemiro who you would think automatically comes into the team.
If you've just played like that against Liverpool the other night, it's a bit harsh if you lose your place straight away to a new signing.
But how do you say to Casemiro 'you sit on the bench at St Mary's having swapped Real Madrid for us'.
Southampton v Man Utd (12:30 BST)
Will this 30-year-old be making his debut for Manchester United?
Casemiro has five Champions League titles - two more than United.
"Casemiro is fit. He did all the training sessions. He trained first individually and the last days he trained with the team," says United boss Erik ten Hag.
It's Premier League action all the way with 20 games taking place between now and Thursday.
Today, there are seven matches alone with early season leaders Arsenal hosting Fulham in a London derby in the late kick-off.
Before that there are five 3pm games. Will Liverpool finally kick-start their campaign against Bournemouth? Will Chelsea crank up the pressure on Brendan Rodgers and Leicester?
12:30 BST: Southampton v Man Utd
15:00 Brentford v Everton
15:00 Brighton & Hove Albion v Leeds United
15:00 Chelsea v Leicester City
15:00 Liverpool v Bournemouth
15:00 Man City v Crystal Palace
17:30 Arsenal v Fulham
Are Manchester United's troubles over or was the win over Liverpool simply a case of papering over the cracks?
United fans hit the road to Southampton bright and early this morning to find out.
Their team's past seven away games have ended: LLLLLLL.
Will they end their horrific away form and secure back-to-back Premier League wins for the first time since FEBRUARY?