Sadly Oriane Jean-François isn't going to be able to continue and she is taken off on a stretcher.

Clare Hunt replaces her in the centre of defence.

Image source, Reuters

While we hope Oriane Jean-François is going to be okay, this break in play will be most welcome for the Manchester United players, who are now having a chat about how they can change the balance of play in their favour.

This doesn't look good for Oriane Jean-François. She twists challenging for the ball and appears to have really hurt her ankle. She's down on the pitch and receiving treatment.

Emma Sanders
BBC Sport at Leigh Sports Village

United are still all over the shop at the back.

Jayde Riviere has been getting constant instructions from Marc Skinner on her defensive positioning.

She doesn't seem to know where to go when PSG attack down their right-hand side. Hannah Blundell has been getting overrun too.

As soon as the game pauses to treat an injury, Skinner shouts "Jayde, come over here!" And they are going through it all again.

Marc Skinner is making some on the fly tactical tweaks to try and counter this dominant start by the visitors.

Maya Le Tissier urges her team-mates to calm things down a bit. The hosts really need a long, boring spell of possession just to build some confidence.

Emma Sanders
BBC Sport at Leigh Sports Village

This has been a terrible start for Manchester United. They can't keep gifting these opportunities.

Paris St-Germain should be ahead! The fans react in Leigh Sports Village with a rendition of "United", though a little anxiously.

Marc Skinner has been busy on the touchline.

Image source, Reuters

This has been a really determined start by PSG and Manchester United have barely had chance to put together a few passes.

The visitors are on the attack again as Tabitha Chawinga cuts the ball back for Lieke Martens, who stabs wide from close range.

Huge save from Mary Earps as PSG come forward again before Sandy Baltimore is put in on goal but her shot is beaten away by the Manchester United and England goalkeeper.

PSG almost spoil the party immediately with a devastatingly quick attack as a ball over the top sends Tabitha Chawinga away, she cuts inside before thumping an effort that is cleared off the line by Katie Zelem.

Huge roar from the fans in attendance - great atmosphere - and we are under way.

Manchester United are on a run of nine games unbeaten on home soil and they will be looking to extend that domestic form into Europe tonight.

Last Friday they drew 2-2 at home to Arsenal, with a last-minute goal by the Gunners denying the Red Devils victory.

The players are out on the pitch, Leigh Sports Village about to play out the Champions League anthem for the first time.

Image source, Reuters

Image source, Getty Images

PSG came second in the French top flight last season and are two-time Women's Champions League finalists.

Despite being only three league games into their season, PSG have already seen a change in managers as Gerard Precheur stepped down from his role head coach last month, with his son and former assistant manager Jocelyn Precheur taking interim charge.

The interim boss has top players to choose from, with Marie-Antoinette Katoto, Lieke Martens and Jackie Groenen - a former United player - in PSG's squad.

Former Manchester United goalkeeper David de Gea posted on social media that he was back in Manchester and the reason for that being he is here tonight to support the home team.

Emma Sanders
BBC Sport at Leigh Sports Village

Image source, BBC Sport

Manchester United forward Geyse, who joined from Barcelona in the summer, knows a thing or two about the Champions League.

She came on as a substitute for the last 20 minutes of Barcelona's victory over Wolfsburg in the final last season and is on the bench for United today.

Geyse hopes she can now help drive United's squad towards European success.

"I have the ambition to put the gold medal back on my chest!" she says in today's match programme.

"It's a very good feeling that I want to repeat again. I know that I will conquer again, certainly, and I aim to do that with Manchester United.

"We can be the best. We have the squad to be the best."

Image source, Getty Images

The qualifying format for the Champions League is a bit unusual in that the draw is split into two separate pathways: the ‘champions’ path for domestic league champions and a ‘league’ path for those sides who did not win their divisions.

Manchester United boss Marc Skinner will be hoping his United side don't fall to the same fate as Arsenal, who were knocked out of the first round of qualifying by Paris FC.

"Teams in England have a much harder qualification route than other teams. I'm sure PSG don't want to be playing us right now," he said.

"When I look at some of the teams who will make the group stages from the other section, it just doesn't seem right."

Manchester United defender Gabby George, speaking to MUTV: "It is exciting for everyone.

"The last game we had a really good home support and we want to get everyone cheering again. Manchester United fans are crazy and come in numbers every time and we expect nothing different tonight. We want to put on a show.

"I feel I have settled in well, all the staff have been great and the fans even better."

England boss Sarina Wiegman is an interested observer at Leigh Sports Village tonight.

The atmosphere is really starting to build as kick off approaches on what is a pretty pleasant night in Leigh. Coat weather, but not too chilly.

Emma Sanders
BBC Sport at Leigh Sports Village

Image source, BBC Sport

Manchester United mascot "Fred the Red" has been here since at least 18:00 BST meeting fans and posing for photos.

This is the type of fixture which might attract new supporters to the women's game given the stature of both clubs. That's what United are hoping for anyway.

There were just over 6,000 tickets sold before doors opened tonight and there could be a couple of hundred more sold at the gate.

I've already spotted a few shirts with men's players' names on the back mixed in with the usual "Toone"s, "Galton"s and "Turner"s.

I wonder whether we'll see any of the new Nike Mary Earps' goalkeeper shirts that went on sale yesterday and sold out within hours...

Manchester United boss Marc Skinner tells MUTV that he's picked a team tonight that he feels can adapt to whatever PSG throw at them.

"They [PSG] can play a 4-3-3 and a 5-3-2 so we have players who can adapt to both formations.

"We wanted to freshen things up too but for us it is about having adaptability on the field so we can change shape quickly.

"We have adapted for this game."