England left needing new gameplanpublished at 15:41 Greenwich Mean Time 26 February 2022
England v Wales (16:45 GMT)
If you're just catching up on the whole Manu Tuilagi in-out saga, the centre was supposed to make his big return from a hamstring injury.
Hours after being named in the starting side, he had to withdraw because he'd injured the same hamstring, albeit much less severely.
His absence is likely to mean England need a new gameplan. Tuilagi would have been able to punch his way through Wales' defence but Daly and Slade lack that physical heft.
We'll have to wait and see how the hosts cope with that.