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LIVE: Serena Williams loses 7-5 6-7 (4-7) 6-1 to Ajla Tomljanovic in US Open third round
Defeat is last match of 23-time Grand Slam single champion's career
Andy Murray loses 6-4 6-4 6-7 (1-7) 6-3 to Matteo Berrettini
Jack Draper retires injured in third set against Karen Khachanov
Top seeds Joe Salisbury & Rajeev Ram reach men's doubles third round but Jamie Murray & Bruno Soares lose
Day five of final Grand Slam of year at Flushing Meadows
*Tomljanovic 7-5 4-5 Williams
David Law
Commentator on BBC Radio 5 Live
The murmur you can hear is from 23,000 people who are suddenly concerned that this may be going horribly wrong for Serena Williams.
*Tomljanovic 7-5 4-5 Williams
She needs only one. A Williams double fault hands Tomljanovic the break.
Crikey.
Tomljanovic 7-5 3-5 Williams*
This set is remarkable.
After that epic of an eighth game, Ajla Tomljanovic has raced into a 40-15 lead on Serena Williams' serve and has two break points.
I can't type quick enough.
Tomljanovic 7-5 3-5 Williams*
Laura Robson
Former British number one at Flushing Meadows
I know she said she would channel Djokovic, but Tomljanovic could do with channeling a bit of Daniil Medvedev.
Tomljanovic 7-5 3-5 Williams*
Finally, we have a breakthrough.
On her sixth opportunity, Ajla Tomljanovic secures the hold and everyone can breathe again.
Serena Williams to serve for the set.
*Tomljanovic 7-5 2-5 Williams
David Law
Commentator on BBC Radio 5 Live
If Tomljanovic reacts again to this crowd, it could be lift-off...
*Tomljanovic 7-5 2-5 Williams
Ajla Tomljanovic is showing signs of frustrations at the crowd's overwhelming support of her opponent.
Apart from her box, Tomljanovic fans are few and far between.
*Tomljanovic 7-5 2-5 Williams
Oh my word, this is never-ending.
Williams can't return off the backhand and we're at an eighth deuce.
*Tomljanovic 7-5 2-5 Williams
A third consecutive advantage for Ajla Tomljanovic goes begging as Serena Williams powers a forehand into the corner. She can't convert a fourth either, Williams playing superb shots to stop her in her tracks.
The next advantage goes Williams' way and it's a fourth break and set point...
*Tomljanovic 7-5 2-5 Williams
Tomljanovic gets an advantage but like Williams, cannot convert her opportunity, once again sending a scooped backhand over the baseline.
She gets another chance for the hold but this time it's Williams who puts too much behind a return, and we're back at deuce for a *checks* fifth time.
*Tomljanovic 7-5 2-5 Williams
The net shall not let Williams pass. Back to deuce. Again.
*Tomljanovic 7-5 2-5 Williams
Serena Williams brings play into the centre and crashes home a volley at the net to earn a third break and set point.
*Tomljanovic 7-5 2-5 Williams
Laura Robson
Former British number one at Flushing Meadows
The way Serena is hitting, it is impressive that Tomljanovic has even managed to stay in this set.
*Tomljanovic 7-5 2-5 Williams
A first set point goes begging for an inpatient Serena Williams, but she soon finds herself with a second as Ajla Tomljanovic sends a backhand a touch long.
A Williams backhand return is judged out and it's back to deuce.
Image source, Getty Images*Tomljanovic 7-5 2-5 Williams
A 0-30 lead for Serena Williams is soon cancelled out, as the American great sends a forehand return sailing into the net.
But then smashing (literally) play at the net hands her break and set point...
*Tomljanovic 7-5 2-5 Williams
Gigi Salmon
BBC Sport tennis commentator
Serena's mum, Oracene, looks as cool as a cucumber in the player box, as does Venus. They have done this hundreds of times before.
*Tomljanovic 7-5 2-5 Williams
Williams lets out a huge roar as she wins the point off the forehand to get the advantage, and an even bigger one as she gets the hold. As one, Ashe leaps to its feet in celebration.
That was an important hold, to stop Ajla Tomljanovic from getting any real momentum after those successive game wins.
Win one more game and the set is hers.
Tomljanovic 7-5 2-4 Williams*
Serena Williams has two game points but she lets Ajla Tomljanovic back into it, and she takes a moment to compose herself before serving at 40-30 up. It does little to help as she misfires a forehand well wide.
Deuce.
Tomljanovic 7-5 2-4 Williams*
Boom. Ajla Tomljanovic isn't out of this set just yet.
The Wimbledon quarter-finalist races to 40-0, but despite conceding the next point, grabs the hold with a backhand directed towards the corner.
Very little noise from the Ashe crowd in reaction to that hold...
Jonathan Jurejko
BBC Sport at Flushing Meadows
NBA star Ben Simmons gets roundly booed when he appears on the big screen.
Maybe not what he needs after splitting up with British television star Maya Jama this week.
The man might have a broken heart, people!
Presume there are a lot of New York Knicks fans in. Simmons is a star of the Brooklyn Nets.
Or maybe they are fans of Cannonball and have got Maya's back. Who knows.