Team news
Brentford boss Thomas Frank has reported no fresh injury concerns following Thursday's win at Nottingham Forest.
This game may come too soon for Aaron Hickey and Igor Thiago, while Vitaly Janelt, Joshua Dasilva and Fabio Carvalho remain sidelined.
Manchester United wing-back Noussair Mazraoui is ruled out after being forced off during Thursday's Europa League victory against Athletic Club.
Head coach Ruben Amorim says "players under risk of injury will not play" on Sunday, with next week's semi-final second leg in mind.
Amad Diallo made his comeback from an ankle issue in midweek, with Matthijs de Ligt also returning to the matchday squad, while Chido Obi is back in contention after being ineligible for the win in Bilbao.
Match facts
Head-to-head
Brentford's only win in the past 12 meetings in all competitions was 4-0 at home in August 2022.
Ten of Manchester United's 12 Premier League goals against the Bees have been scored in the second half, with three of the past five netted after the 90th minute.
Brentford
They are vying to win three league games in a row for the first time since November 2023.
Victory against Brighton on 19 April ended their run of eight home league matches without a win (D3, L5).
Brentford have won 52.8% of their aerial duels in this season's Premier League, the second highest figure in the division.
They are the only side with two players directly involved in at least 20 Premier League goals this season – Bryan Mbeumo has scored18 and provided six assists, while Yoane Wissa has 17 goals and three assists.
Mbeumo has scored 11 Premier League home goals this season, one more than his combined total in his first three seasons in the competition.
Wissa has netted each of his past three Premier League appearances – he has never scored in a four in a row.
Manchester United
Manchester United have won seven of nine Europa League games under Ruben Amorim, compared to six victories in 23 top-flight fixtures since his appointment.
Amorim's United have also averaged 2.67 goals per game in Europe but just 1.2 in the league.
They have failed to win each of their past five top-flight matches (D2, L3), their worst run for six years. The last time they went six league games without a win was in December 2015, under the management of Louis van Gaal.
The Reds have won three of their last 21 Premier League games in London (D5, L13), with all three victories coming against Fulham.
Bruno Fernandes has been directly involved in 35 goals in league and cup this season, scoring 19 and assisting 16. Only Mohamed Salah, with 56 goal involvements, has a higher total for a Premier League club in all competitions this term.
Fernandes is two shy of 100 goals for United in all competitions.
