Team news
Chelsea goalkeeper Robert Sanchez should return after a minor knock forced him to miss Thursday's Conference League win over Djurgarden.
Forward Christopher Nkunku also faces a fitness test but head coach Enzo Maresca has reported no fresh injury concerns after their midweek victory.
Liverpool head coach Arne Slot says he will rotate his side for the final four matches, with the likes of Harvey Elliott, Curtis Jones and Diogo Jota all vying for a place in the starting line-up.
Right-back Conor Bradley has returned to training and is expected to be involved.
Match facts
Head-to-head
Liverpool are unbeaten in 10 league and cup meetings with Chelsea (W7, D3).
If the Reds avoid defeat it would equal their longest unbeaten run in this fixture, which was set between 1985 and 1990.
The past five clashes between the sides at Stamford Bridge have produced just three goals.
Chelsea
Chelsea are unbeaten in five Premier League matches, winning three and drawing two.
The Blues have won five of their previous seven home games in all competitions, keeping a clean sheet in each victory.
Enzo Maresca's side have earned 17 points from their last eight league matches – they collected nine points from their previous 10 beforehand.
This is Chelsea's seventh Premier League fixture against a side crowned champions, the most of any team. They've won just one of the six previous clashes (D2, L3).
Cole Palmer has gone 18 games without a goal in all competitions since he scored in a 2-2 home draw with Bournemouth in January.
Liverpool
Liverpool have won three successive league matches and claimed a 20th top-flight title last weekend with a 5-1 home thrashing of Spurs.
However, the Reds have lost two of their past three visits to London, losing 3-2 at Fulham and 1-0 to Tottenham, winning the other 2-0 at Brentford.
The Merseysiders have failed to score only once in 34 Premier League games this season – a 1-0 defeat by Nottingham Forest at Anfield in September.
Arne Slot is the fourth Liverpool manager to win the top-flight title in his first season, emulating Matt McQueen (1922-23), Joe Fagan (1983-84), and Kenny Dalglish (1985-86).
Slot is vying to become the third Liverpool manager to win both of his opening two league games against Chelsea, after Bill Shankly and Roy Evans.
Mohamed Salah's goal at Anfield last weekend ended a barren run of six games without scoring in all competitions.