Team news
Brentford full-back Rico Henry could be included in a matchday squad for just the third time this season.
Midfielder Mathias Jensen is back in training after missing the past two games through illness, but this fixture will come too soon for Aaron Hickey and Gustavo Nunes.
Chelsea defender Wesley Fofana has been ruled out with a muscle problem.
The Blues are also without midfielder Romeo Lavia, while Mykhailo Mudryk remains suspended.
Match facts
Head-to-head
Chelsea are unbeaten in seven league and cup visits to Brentford since a 1-0 defeat in October 1938 (W4, D3).
The Blues are seeking to complete a second league double over the Bees and first since the 1946-47 campaign.
Brentford
Brentford have gone seven Premier League games without a home victory, drawing twice and losing five times.
They are the only top-flight side without a home clean sheet this season and have failed to stop the opposition scoring in all 18 of their league and cup fixtures at the Gtech Community Stadium.
The Bees have lost 10 of their last 16 Premier League London derbies (W3, D3).
They could lose three successive home league derbies for the first time since January 1982.
Bryan Mbeumo has scored three goals and provided three assists in his last five Premier League games against Chelsea.
Yoane Wissa has been involved in 13 goals in his last 14 Premier League home matches, registering 11 goals and two assists.
Chelsea
Chelsea could lose five successive Premier League away matches for the first time since a similar run between October and December 2000.
The Blues have won just two of their past 10 away games in all competitions, with those triumphs coming in Kazakhstan and Denmark.
They have gone eight domestic matches without a victory on the road, drawing two and losing six since a 4-3 win at Tottenham in early December.
However, Chelsea have won five of their past six matches in all competitions, losing the other.
Cole Palmer ended a run of 15 Premier League appearances without an assist by setting up Enzo Fernandez's winner versus Tottenham on Thursday.